Imperial College London

professor neil fairweather

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Microbiology
 
 
 
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Contact

 

+44 (0)20 7594 5247n.fairweather

 
 
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Location

 

1.44Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

125 results found

Scott N, Qazi O, Wright MJ, Fairweather NF, Deonarain MPet al., 2010, Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding, MOLECULAR IMMUNOLOGY, Vol: 47, Pages: 1931-1941, ISSN: 0161-5890

JOURNAL ARTICLE

Emerson JE, Reynolds CB, Fagan RP, Shaw HA, Goulding D, Fairweather NFet al., 2009, A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein, MOLECULAR MICROBIOLOGY, Vol: 74, Pages: 541-556, ISSN: 0950-382X

JOURNAL ARTICLE

Fagan RP, Albesa-Jove D, Qazi O, Svergun DI, Brown KA, Fairweather NFet al., 2009, Structural insights into the molecular organization of the S-layer from Clostridium difficile, MOLECULAR MICROBIOLOGY, Vol: 71, Pages: 1308-1322, ISSN: 0950-382X

JOURNAL ARTICLE

Goulding D, Thompson H, Emerson J, Fairweather NF, Dougan G, Douce GRet al., 2009, Distinctive Profiles of Infection and Pathology in Hamsters Infected with Clostridium difficile Strains 630 and B1, INFECTION AND IMMUNITY, Vol: 77, Pages: 5478-5485, ISSN: 0019-9567

JOURNAL ARTICLE

Johnston L, Mawas F, Tierney R, Qazi O, Fairweather N, Sesardic Det al., 2009, Transcutaneous delivery of tetanus toxin Hc fragment induces superior tetanus toxin neutralizing antibody response compared to tetanus toxoid, HUMAN VACCINES, Vol: 5, Pages: 230-236, ISSN: 1554-8619

JOURNAL ARTICLE

Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, Croucher N, Mastroeni P, Scott P, Raisen C, Mottram L, Fairweather NF, Wren BW, Parkhill J, Dougan Get al., 2009, Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts, INFECTION AND IMMUNITY, Vol: 77, Pages: 3661-3669, ISSN: 0019-9567

JOURNAL ARTICLE

Qazi O, Hitchen P, Tissot B, Panico M, Morris HR, Dell A, Fairweather Net al., 2009, Mass spectrometric analysis of the S-layer proteins from Clostridium difficile demonstrates the absence of glycosylation, JOURNAL OF MASS SPECTROMETRY, Vol: 44, Pages: 368-374, ISSN: 1076-5174

JOURNAL ARTICLE

Andreu A, Fairweather N, Miller AD, 2008, Clostridium neurotoxin fragments as potential targeting moieties for liposomal gene delivery to the CNS, CHEMBIOCHEM, Vol: 9, Pages: 219-231, ISSN: 1439-4227

JOURNAL ARTICLE

Emerson JE, Stabler RA, Wren BW, Fairweather NFet al., 2008, Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 57, Pages: 757-764, ISSN: 0022-2615

JOURNAL ARTICLE

Scott N, Reynolds CB, Wright MJ, Qazi O, Fairweather N, Deonarain MPet al., 2008, Single-chain Fv phage display propensity exhibits strong positive correlation with overall expression levels, BMC BIOTECHNOLOGY, Vol: 8, ISSN: 1472-6750

JOURNAL ARTICLE

Wright A, Drudy D, Kyne L, Brown K, Fairweather NFet al., 2008, Immunoreactive cell wall proteins of Clostridium difficile identified by human sera, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 57, Pages: 750-756, ISSN: 0022-2615

JOURNAL ARTICLE

Qazi O, Bolgiano B, Crane D, Svergun DI, Konarev PV, Yao Z-P, Robinson CV, Brown KA, Fairweather Net al., 2007, The H-C fragment of tetanus toxin forms stable, concentration-dependent dimers via an intermolecular disulphide bond, JOURNAL OF MOLECULAR BIOLOGY, Vol: 365, Pages: 123-134, ISSN: 0022-2836

JOURNAL ARTICLE

Qazi O, Brailsford A, Wright A, Faraar J, Campbell J, Fairweather Net al., 2007, Identification and characterization of the surface-layer protein of Clostridium tetani, FEMS MICROBIOLOGY LETTERS, Vol: 274, Pages: 126-131, ISSN: 0378-1097

JOURNAL ARTICLE

Fishman PS, Matthews CC, Parks DA, Box M, Fairweather NFet al., 2006, Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin, JOURNAL OF NEUROSCIENCE RESEARCH, Vol: 83, Pages: 1540-1543, ISSN: 0360-4012

JOURNAL ARTICLE

Qazi O, Sesardic D, Tierney R, Soderback Z, Crane D, Bolgiano B, Fairweather Net al., 2006, Reduction of the ganglioside binding activity of the tetanus toxin H-C fragment destroys immunogenicity: Implications for development of novel tetanus vaccines, INFECTION AND IMMUNITY, Vol: 74, Pages: 4884-4891, ISSN: 0019-9567

JOURNAL ARTICLE

Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeno-Tarrraga AM, Wang H, Holden MTG, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill Jet al., 2006, The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome, NATURE GENETICS, Vol: 38, Pages: 779-786, ISSN: 1061-4036

JOURNAL ARTICLE

Chargelegue D, Drake PAW, Obregon P, Prada A, Fairweather N, Ma JKCet al., 2005, Highly immunogenic and protective recombinant vaccine candidate expressed in transgenic plants, INFECTION AND IMMUNITY, Vol: 73, Pages: 5915-5922, ISSN: 0019-9567

JOURNAL ARTICLE

Keith KE, Oyston PC, Crossett B, Fairweather NF, Titball RW, Walsh TR, Brown KAet al., 2005, Functional characterization of OXA-57, a class D beta-lactamase from Burkholderia pseudomallei, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol: 49, Pages: 1639-1641, ISSN: 0066-4804

JOURNAL ARTICLE

Rupnik M, Dupuy B, Fairweather NF, Gerding DN, Johnson S, Just I, Lyerly DM, Popoff MR, Rood JI, Sonenshein AL, Thelestam M, Wren BW, Wilkins TD, von Eichel-Streiber Cet al., 2005, Revised nomenclature of Clostridium difficile toxins and associated genes, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 54, Pages: 113-117, ISSN: 0022-2615

JOURNAL ARTICLE

Tregoning JS, Clare S, Bowe F, Edwards L, Fairweather N, Qazi O, Nixon PJ, Maliga P, Dougan G, Hussell Tet al., 2005, Protection against tetanus toxin using a plant-based vaccine, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 35, Pages: 1320-1326, ISSN: 0014-2980

JOURNAL ARTICLE

Wright A, Wait R, Begum S, Crossett B, Nagy J, Brown K, Fairweather Net al., 2005, Proteomic analysis of cell surface proteins from Clostridium difficile, PROTEOMICS, Vol: 5, Pages: 2443-2452, ISSN: 1615-9853

JOURNAL ARTICLE

Drudy D, Calabi E, Kyne LNF, Sougioultzis S, Kelly E, Fairweather N, Kelly CPet al., 2004, Human antibody response to surface layer proteins in Clostridium difficile infection, FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, Vol: 41, Pages: 237-242, ISSN: 0928-8244

JOURNAL ARTICLE

Box M, Parks DA, Knight A, Hale C, Fishman PS, Fairweather NFet al., 2003, A multi-domain protein system based on the H-C fragment of tetanus toxin for targeting DNA to neuronal cells, JOURNAL OF DRUG TARGETING, Vol: 11, Pages: 333-343, ISSN: 1061-186X

JOURNAL ARTICLE

Duc L, Hong HA, Fairweather N, Ricca E, Cutting SMet al., 2003, Bacterial spores as vaccine vehicles, INFECTION AND IMMUNITY, Vol: 71, Pages: 2810-2818, ISSN: 0019-9567

JOURNAL ARTICLE

Foynes S, Holley JL, Garmory HS, Titball RW, Fairweather NFet al., 2003, Vaccination against type F botulinum toxin using attenuated Salmonella enterica var Typhimurium strains expressing the BoNT/F HC fragment, VACCINE, Vol: 21, Pages: 1052-1059, ISSN: 0264-410X

JOURNAL ARTICLE

Mathieu R, Lim J, Simpson P, Prasannan S, Fairweather N, Matthews Set al., 2003, Resonance assignment and topology of a clostridial repetitive oligopeptide (CROP) region of toxin A from Clostridium difficile, JOURNAL OF BIOMOLECULAR NMR, Vol: 25, Pages: 83-84, ISSN: 0925-2738

JOURNAL ARTICLE

Tregoning JS, Nixon P, Kuroda H, Svab Z, Clare S, Bowe F, Fairweather N, Ytterberg J, van Wijk KJ, Dougan G, Maliga Pet al., 2003, Expression of tetanus toxin Fragment C in tobacco chloroplasts, NUCLEIC ACIDS RESEARCH, Vol: 31, Pages: 1174-1179, ISSN: 0305-1048

JOURNAL ARTICLE

Calabi E, Calabi F, Phillips AD, Fairweather NFet al., 2002, Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues, INFECTION AND IMMUNITY, Vol: 70, Pages: 5770-5778, ISSN: 0019-9567

JOURNAL ARTICLE

Calabi E, Fairweather N, 2002, Patterns of sequence conservation in the S-layer proteins and related sequences in Clostridium difficile, JOURNAL OF BACTERIOLOGY, Vol: 184, Pages: 3886-3897, ISSN: 0021-9193

JOURNAL ARTICLE

Fairweather N, Sinha K, Black I, Emsley P, Fotinou C, Isaacs Net al., 2002, Structural and functional studies of the ganglisoide binding activities of tetanus toxin, NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, Vol: 365, Pages: R19-R19, ISSN: 0028-1298

JOURNAL ARTICLE

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