Imperial College London

professor neil fairweather

Faculty of Natural SciencesDepartment of Life Sciences

Emeritus Professor



+44 (0)20 7594 5247n.fairweather




1.44Flowers buildingSouth Kensington Campus






BibTex format

author = {Fagan, R and Fairweather, N},
doi = {10.1007/978-1-60327-365-7_8},
journal = {Methods Mol Biol},
pages = {117--134},
title = {Dissecting the cell surface.},
url = {},
volume = {646},
year = {2010}

RIS format (EndNote, RefMan)

AB - The bacterial cell surface is an important structure as it mediates interactions with the external environment. In the case of pathogens like Clostridium difficile, the cell wall and its components also have to mediate interactions with the host cells and their products. In this chapter we discuss the various methods used for dissecting the cell surface and the biochemical and immunological procedures that are commonly used to analyse the properties of the proteins within the cell wall. A major consideration is the S-layer which in C. difficile shows considerable variation in sequence and between strains, a property which is also reflected in its antigenic properties.
AU - Fagan,R
AU - Fairweather,N
DO - 10.1007/978-1-60327-365-7_8
EP - 134
PY - 2010///
SP - 117
TI - Dissecting the cell surface.
T2 - Methods Mol Biol
UR -
UR -
VL - 646
ER -