My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.
Current Group members
PREVIOUS GROUP MEMBERS
Nollet M, Wisden W, Franks N, Sleep deprivation and stress - a reciprocal relationship, Interface Focus, ISSN:2042-8901
Harding E, Franks N, Wisden W, 2019, Sleep and thermoregulation, Current Opinion in Physiology, ISSN:2468-8673
et al., 2019, Noble gas neuroprotection: Xenon and argon protect against hypoxic-ischaemic injury in rat hippocampus in vitro via distinct mechanisms, British Journal of Anaesthesia, Vol:123, ISSN:1471-6771, Pages:601-609
et al., 2019, Galanin neurons unite sleep homeostasis and alpha2 adrenergic sedation, Current Biology, Vol:29, ISSN:1879-0445, Pages:3315-3322.e3
et al., 2019, Xenon prevents early neuronal loss and neuroinflammation in a rat model of traumatic brain injury, BJA Research Forum / Anaesthetic Research Society, Elsevier, Pages:e508-e509, ISSN:0007-0912