My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep.
My laboratory is merged with that of Bill Wisden and our joint website can be found here: franks-wisden-lab.
Current Group members
PREVIOUS GROUP MEMBERS
Franks NP, Wisden W, 2021, The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation, Science, Vol:374, ISSN:0036-8075, Pages:556-559
et al., 2021, Nitric oxide synthase neurons in the preoptic hypothalamus are NREM and REM sleep-active and lower body temperature, Frontiers in Neuroscience, Vol:15, ISSN:1662-453X
et al., 2021, Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior, Molecular Psychiatry, Vol:26, ISSN:1359-4184, Pages:5213-5228
et al., 2021, Xenon prevents neuroinflammation in a novel model of blast traumatic brain injury in rats, LIPPINCOTT WILLIAMS & WILKINS, Pages:947-947, ISSN:0003-2999
et al., 2021, Moderate hypothermia combined with xenon, but not hypothermia alone, reduces secondary injury development after traumatic brain injury in rats, LIPPINCOTT WILLIAMS & WILKINS, Pages:946-946, ISSN:0003-2999