Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics



+44 (0)20 7594 7629n.franks Website




401ASir Ernst Chain BuildingSouth Kensington Campus





My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.

My publications from Google Scholar

My profile from ORCID

Current Group members

Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan



Yu X, Ba W, Ma Y, et al., 2019, GABA and glutamate neurons in the VTA regulate sleep and wakefulness, Nature Neuroscience, Vol:22, ISSN:1097-6256, Pages:106-+

Scammell TE, Jackson AC, Franks NP, et al., 2018, Histamine: Neural circuits and new medications., Sleep

Paul EJ, Kalk E, Tossell K, et al., 2018, nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta, Eneuro, Vol:5, ISSN:2373-2822

Harding EC, Yu X, Miao A, et al., 2018, A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus, Current Biology, Vol:28, ISSN:0960-9822, Pages:2263-+

Campos-Pires R, Koziakova M, Yonis A, et al., 2018, Xenon Protects against Blast-Induced Traumatic Brain Injury in an In Vitro Model, Journal of Neurotrauma, Vol:35, ISSN:0897-7151, Pages:1037-1044

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