Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics



+44 (0)20 7594 7629n.franks Website




401ASir Ernst Chain BuildingSouth Kensington Campus





My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.

My publications from Google Scholar

My profile from ORCID

Current Group members

Nick and BillWei and RaquelKyoko and GiuliaYing and LedaBerta and DavidEd and ChrisEd and XiaoBryan and Mathieu



Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan



Nollet M, Wisden W, Franks N, Sleep deprivation and stress - a reciprocal relationship, Interface Focus, ISSN:2042-8901

Harding E, Franks N, Wisden W, 2019, Sleep and thermoregulation, Current Opinion in Physiology, ISSN:2468-8673

Koziakova M, Harris K, Edge C, et al., 2019, Noble gas neuroprotection: Xenon and argon protect against hypoxic-ischaemic injury in rat hippocampus in vitro via distinct mechanisms, British Journal of Anaesthesia, Vol:123, ISSN:1471-6771, Pages:601-609

Ma Y, Miracca G, Yu X, et al., 2019, Galanin neurons unite sleep homeostasis and alpha2 adrenergic sedation, Current Biology, Vol:29, ISSN:1879-0445, Pages:3315-3322.e3


Campos-Pires R, Mohamed-Ali N, Balaet M, et al., 2019, Xenon prevents early neuronal loss and neuroinflammation in a rat model of traumatic brain injury, BJA Research Forum / Anaesthetic Research Society, Elsevier, Pages:e508-e509, ISSN:0007-0912

More Publications