Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics



+44 (0)20 7594 7629n.franks Website




401ASir Ernst Chain BuildingSouth Kensington Campus





My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.

My publications from Google Scholar

My profile from ORCID

Current Group members

Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan



Ye Z, Yu X, Houston CM, et al., 2017, Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different γ Subunits., Front Cell Neurosci, Vol:11, ISSN:1662-5102

Wisden W, Yu X, Franks NP, 2017, GABA Receptors and the Pharmacology of Sleep., Handb Exp Pharmacol, ISSN:0171-2004

Azzopardi D, Robertson NJ, Bainbridge A, et al., 2016, Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial, Lancet Neurology, Vol:15, ISSN:1474-4422, Pages:145-153


Wisden W, Yu X, Ye Z, et al., 2016, Histamine and gamma-amino butyric acid co-transmission promotes arousal, 23rd Congress of the European-Sleep-Research-Society, WILEY-BLACKWELL, Pages:26-26, ISSN:0962-1105

Pires Santos e Sousa RDC, Armstrong SP, Sebastiani A, et al., 2016, THE NOBLE GAS XENON REDUCES SECONDARY INJURYAND IMPROVES LONG-TERM LOCOMOTOR FUNCTION AFTER TRAUMATIC BRAIN INJURY IN RODENTS, 27th International Symposium on Cerebral Blood Flow, Metabolism and Function / 12th International Conference on Quantification of Brain Function with PET, SAGE PUBLICATIONS INC, Pages:308-309, ISSN:0271-678X

More Publications