Imperial College London

Professor Nick Franks, FRS

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Biophysics and Anaesthetics



+44 (0)20 7594 7629n.franks Website




401ASir Ernst Chain BuildingSouth Kensington Campus





My central research interest is in understanding how general anaesthetics act. I have worked on this problem mainly at the molecular and cellular levels but more recently I have become interested in how anaesthetics act at the level of neuronal networks and have been pursuing the possibility that the sedative and hypnotic actions of general anaesthetics may be mediated through the same neuronal pathways that control natural sleep. I work closely with Bill Wisden and Stephen Brickley.

My publications from Google Scholar

My profile from ORCID

Current Group members

Lily, Alessandro and Chris

Rowan,Valentina,FabiaCigdem, Ed and Rowan



Brickley SG, Wisden W, Franks NP, Modulation of GABA-A receptor function and sleep, Current Opinion in Physiology, ISSN:2468-8673

Campos-Pires R, Koziakova M, Yonis A, et al., 2018, Xenon Protects against Blast-Induced Traumatic Brain Injury in an In Vitro Model., J Neurotrauma

Gelegen C, Miracca G, Ran MZ, et al., 2018, Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation., Curr Biol

Yu X, Franks NP, Wisden W, 2018, Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems, Frontiers in Neural Circuits, Vol:12, ISSN:1662-5110

Ye Z, Yu X, Houston CM, et al., 2017, Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAAReceptors with Different γ Subunits., Front Cell Neurosci, Vol:11, ISSN:1662-5102

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