Imperial College London
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ProfessorNeenaModi

Faculty of Medicine, School of Public Health

Vice-Dean (International Activities) Faculty of Medicine
 
 
 
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Contact

 

+44 (0)20 3315 5102n.modi Website

 
 
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Assistant

 

Miss Angela Rochester +44 (0)20 7594 0937

 
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Location

 

G4.2Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Helenius:2017:10.1542/peds.2017-1264,
author = {Helenius, K and Sjors, G and Shah, PS and Modi, N and Reichman, B and Morisaki, N and Kusuda, S and Lui, K and Darlow, BA and Bassler, D and Hakansson, S and Adams, M and Vento, M and Rusconi, F and Isayama, T and Lee, SK and Lehtonen, L},
doi = {10.1542/peds.2017-1264},
journal = {Pediatrics},
title = {Survival in Very Preterm Infants: An International Comparison of 10 National Neonatal Networks},
url = {http://dx.doi.org/10.1542/peds.2017-1264},
volume = {140},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVES: To compare survival rates and age at death among very preterm infants in 10 national and regional neonatal networks.METHODS: A cohort study of very preterm infants, born between 24 and 29 weeks’ gestation and weighing <1500 g, admitted to participating neonatal units between 2007 and 2013 in the International Network for Evaluating Outcomes of Neonates. Survival was compared by using standardized ratios (SRs) comparing survival in each network to the survival estimate of the whole population.RESULTS: Network populations differed with respect to rates of cesarean birth, exposure to antenatal steroids and birth in nontertiary hospitals. Network SRs for survival were highest in Japan (SR: 1.10; 99% confidence interval: 1.08–1.13) and lowest in Spain (SR: 0.88; 99% confidence interval: 0.85–0.90). The overall survival differed from 78% to 93% among networks, the difference being highest at 24 weeks’ gestation (range 35%–84%). Survival rates increased and differences between networks diminished with increasing gestational age (GA) (range 92%–98% at 29 weeks’ gestation); yet, relative differences in survival followed a similar pattern at all GAs. The median age at death varied from 4 days to 13 days across networks.CONCLUSIONS: The network ranking of survival rates for very preterm infants remained largely unchanged as GA increased; however, survival rates showed marked variations at lower GAs. The median age at death also varied among networks. These findings warrant further assessment of the representativeness of the study populations, organization of perinatal services, national guidelines, philosophy of care at extreme GAs, and resources used for decision-making.
AU  - Helenius,K
AU  - Sjors,G
AU  - Shah,PS
AU  - Modi,N
AU  - Reichman,B
AU  - Morisaki,N
AU  - Kusuda,S
AU  - Lui,K
AU  - Darlow,BA
AU  - Bassler,D
AU  - Hakansson,S
AU  - Adams,M
AU  - Vento,M
AU  - Rusconi,F
AU  - Isayama,T
AU  - Lee,SK
AU  - Lehtonen,L
DO  - 10.1542/peds.2017-1264
PY  - 2017///
SN  - 0031-4005
TI  - Survival in Very Preterm Infants: An International Comparison of 10 National Neonatal Networks
T2  - Pediatrics
UR  - http://dx.doi.org/10.1542/peds.2017-1264
VL  - 140
ER  -
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