Imperial College London
Alternate

Professor Neil Poulter

Faculty of Medicine, School of Public Health

Professor of Preventive Cardiovascular Medicine.
 
 
 
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Contact

 

+44 (0)20 7594 3446n.poulter

 
 
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Assistant

 

Mrs Ranjit Rayat +44 (0)20 7594 3445

 
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Location

 

55Stadium HouseWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Blomster:2017:10.1016/j.diabres.2017.03.015,
author = {Blomster, JI and Zoungas, S and Woodward, M and Neal, B and Harrap, S and Poulter, N and Marre, M and Williams, B and Chalmers, J and Hillis, GS},
doi = {10.1016/j.diabres.2017.03.015},
journal = {Diabetes Research and Clinical Practice},
pages = {212--217},
title = {The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study},
url = {http://dx.doi.org/10.1016/j.diabres.2017.03.015},
volume = {127},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AimsThe relationship between educational level and the risk of all-cause mortality is well established, whereas the association with vascular events in individuals with type 2 diabetes is not well described. Any association may reflect a link with common cardiovascular or lifestyle-based risk factors.MethodsThe relationships between the highest level of educational attainment and major cardiovascular events, microvascular complications and all-cause mortality were explored in a cohort of 11,140 individuals with type 2 diabetes. Completion of formal education before the age of 16 was categorized as a low level of education. Regional differences between Asia, East Europe and Established Market Economies were also assessed.ResultsDuring a median of 5 years of follow up, 1031 (9%) patients died, 1147 (10%) experienced a major cardiovascular event and 1136 (10%) a microvascular event. After adjustment for baseline characteristics and risk factors, individuals with lower education had an increased risk of cardiovascular events (hazard ratio (HR) 1.31, 95% CI 1.16–1.48, p < 0.0001), microvascular events (HR 1.23, 95% CI 1.08–1.39, p = 0.0013) and all-cause mortality (HR 1.34, 95% CI 1.18–1.52, p < 0.0001). In regional analyses the increased risk of studied outcomes associated with lower education was weakest in Established Market Economies and strongest in East Europe.ConclusionsA low level of education is associated with an increased risk of vascular events and death in patients with type 2 diabetes, independently of common lifestyle associated cardiovascular risk factors. The effect size varies between geographical regions.
AU  - Blomster,JI
AU  - Zoungas,S
AU  - Woodward,M
AU  - Neal,B
AU  - Harrap,S
AU  - Poulter,N
AU  - Marre,M
AU  - Williams,B
AU  - Chalmers,J
AU  - Hillis,GS
DO  - 10.1016/j.diabres.2017.03.015
EP  - 217
PY  - 2017///
SN  - 1872-8227
SP  - 212
TI  - The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study
T2  - Diabetes Research and Clinical Practice
UR  - http://dx.doi.org/10.1016/j.diabres.2017.03.015
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000402468500025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/49063
VL  - 127
ER  -
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