Imperial College London

ProfessorNadiaRosenthal

Faculty of MedicineNational Heart & Lung Institute

Chair in Cardiovascular Science&ScientificDirector
 
 
 
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Contact

 

+44 (0)20 7594 2737n.rosenthal

 
 
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Location

 

424W2ICTEM buildingHammersmith Campus

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Summary

 

Summary

Nadia Rosenthal holds a Chair in Cardiovascular Science at Imperial College London, where she started in 2005 as Scientific Director of the Magdi Yacoub Institute, and Head of the Heart Science Centre/Section within NHLI. She now directs a research laboratory in the new Imperial Centre for Translational and Experimental Medicine. She is also Founding Director of the Australian Regenerative Medicine Institute at Monash University in Melbourne, Australia (since 2007), Scientific Head of EMBL Australia (since 2009) and holds an NH&MRC Australia Fellowship (since 2010).

Born in the US, Professor Rosenthal obtained her PhD in 1981 from Harvard Medical School and trained as a postdoctoral fellow at NIH, then directed a biomedical research laboratory at Harvard Medical School, and served for a decade at the New England Journal of Medicine as editor of the Molecular Medicine series. From 2001-2012 she was Senior Scientist and Head of the Mouse Biology Unit at European Molecular Laboratory [EMBL] in Rome, Italy. She is an EMBO member, with numerous awards and honors including the Ferrari-Soave Prize in Cell Biology and a Doctors Honoris Causa from the Pierre and Marie Curie University in Paris and the University of Amsterdam. She participates on numerous Advisory Boards and Committees including the Scientific Advisory Boards of Keystone Symposia, the Centre for Molecular Medicine in Vienna and The Jackson Laboratory in the US. Professor Rosenthal is a Founding Editor of Disease Models and Mechanisms (2007) and Editor-in-Chief of Differentiation (2012). Her research uses mammalian genetics to explore the embryonic development of heart and skeletal muscle and the regeneration of adult tissues.

Professor Rosenthal’s research focuses on muscle and cardiac developmental genetics and the role of growth factors, stem cells and the immune system in tissue regeneration. Her work the biology of insulin-like growth factors has led to significant advances in novel cell-based therapies for muscle ageing and heart disease. She is a global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease, and repair, and is a participant in EUCOMM, the European Conditional Mouse Mutagenesis Program, where she coordinates the selection and production of new Cre driver strains for the international mouse genetics community.

Multimedia

Regeneration and the immune system

inaugural, science, medicine, lecture

Publications

Journals

Furtado MB, Costa MW, Rosenthal NA, 2016, The cardiac fibroblast: Origin, identity and role in homeostasis and disease, Differentiation, Vol:92, ISSN:0301-4681, Pages:93-101

Gallego-Colon E, Villalba M, Tonkin J, et al., 2016, Intravenous delivery of adeno-associated virus 9-encoded IGF-1Ea propeptide improves post-infarct cardiac remodelling, Npj Regenerative Medicine, Vol:1

Pinto AR, Ilinykh A, Ivey MJ, et al., 2016, Revisiting Cardiac Cellular Composition, Circulation Research, Vol:118, ISSN:0009-7330, Pages:400-409

Sattler S, Rosenthal N, 2016, The neonate versus adult mammalian immune system in cardiac repair and regeneration, Biochimica Et Biophysica Acta-molecular Cell Research, Vol:1863, ISSN:0167-4889, Pages:1813-1821

Gallego-Colon E, Sampson RD, Sattler S, et al., 2015, Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction, Mediators of Inflammation, ISSN:0962-9351

More Publications