Imperial College London

Dr. Nimalan Arinaminpathy (Nim Pathy)

Faculty of MedicineSchool of Public Health

Reader in Mathematical Epidemiology
 
 
 
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Contact

 

nim.pathy Website

 
 
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Location

 

Praed StreetSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

47 results found

Trauer JM, Dodd PJ, Gomes MGM, Gomez GB, Houben RM, McBryde ES, Melsew YA, Menzies NA, Arinaminpathy N, Shrestha S, Dowdy DWet al., 2018, The Importance of Heterogeneity to the Epidemiology of Tuberculosis., Clin Infect Dis

Although less well-recognised than for other infectious diseases, heterogeneity is a defining feature of TB epidemiology. To advance toward TB elimination, this heterogeneity must be better understood and addressed. Drivers of heterogeneity in TB epidemiology act at the level of the infectious host, organism, susceptible host, environment and distal determinants. These effects may be amplified by social mixing patterns, while the variable latent period between infection and disease may mask heterogeneity in transmission. Reliance on notified cases may lead to misidentification of the most affected groups, as case detection is often poorest where prevalence is highest. Assuming average rates apply across diverse groups and ignoring the effects of cohort selection may result in misunderstanding of the epidemic and the anticipated effects of control measures. Given this substantial heterogeneity, interventions targeting high-risk groups based on location, social determinants or comorbidities could improve efficiency, but raise ethical and equity considerations.

JOURNAL ARTICLE

Tlhajoane M, Masoka T, Mpandaguta E, Rhead R, Church K, Wringe A, Kadzura N, Arinaminpathy N, Nyamukapa C, Schur N, Mugurungi O, Skovdal M, Eaton JW, Gregson Set al., 2018, A longitudinal review of national HIV policy and progress made in health facility implementation in Eastern Zimbabwe, HEALTH RESEARCH POLICY AND SYSTEMS, Vol: 16, ISSN: 1478-4505

JOURNAL ARTICLE

Fu H, Lin H-H, Hallett TB, Arinaminpathy Net al., 2018, Modelling the effect of discontinuing universal Bacillus Calmette-Guerin vaccination in an intermediate tuberculosis burden setting, VACCINE, Vol: 36, Pages: 5902-5909, ISSN: 0264-410X

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Braham CA, White PJ, Arinaminpathy N, 2018, Management of tuberculosis by healthcare practitioners in Pakistan: A systematic review, PLOS ONE, Vol: 13, ISSN: 1932-6203

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Yuan H-Y, Baguelin M, Kwok KO, Arinaminpathy N, van Leeuwen E, Riley Set al., 2017, The impact of stratified immunity on the transmission dynamics of influenza, EPIDEMICS, Vol: 20, Pages: 84-93, ISSN: 1755-4365

JOURNAL ARTICLE

Arinaminpathy N, Kim IK, Gargiullo P, Haber M, Foppa IM, Gambhir M, Bresee Jet al., 2017, Estimating Direct and Indirect Protective Effect of Influenza Vaccination in the United States, AMERICAN JOURNAL OF EPIDEMIOLOGY, Vol: 186, Pages: 92-100, ISSN: 0002-9262

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Pandey S, Chadha VK, Laxminarayan R, Arinaminpathy Net al., 2017, Estimating tuberculosis incidence from primary survey data: a mathematical modeling approach, INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol: 21, Pages: 366-374, ISSN: 1027-3719

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Mandal S, Chadha VK, Laxminarayan R, Arinaminpathy Net al., 2017, Counting the lives saved by DOTS in India: a model-based approach, BMC MEDICINE, Vol: 15, ISSN: 1741-7015

JOURNAL ARTICLE

Subramanian R, Graham AL, Grenfell BT, Arinaminpathy Net al., 2016, Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines, PLOS COMPUTATIONAL BIOLOGY, Vol: 12, ISSN: 1553-734X

JOURNAL ARTICLE

Arinaminpathy N, Dewan P, 2016, Tuberculosis burden in India's private sector Reply, LANCET INFECTIOUS DISEASES, Vol: 16, Pages: 1329-1329, ISSN: 1473-3099

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Menzies NA, Gomez GB, Bozzani F, Chatterjee S, Foster N, Garcia Baena I, Laurence YV, Qiang S, Siroka A, Sweeney S, Verguet S, Arinaminpathy N, Azman AS, Bendavid E, Chang ST, Cohen T, Denholm JT, Dowdy DW, Eckhoff PA, Goldhaber-Fiebert JD, Handel A, Huynh GH, Lalli M, Lin H-H, Mandal S, McBryde ES, Pandey S, Salomon JA, Suen S-C, Sumner T, Trauer JM, Wagner BG, Whalen CC, Wu C-Y, Boccia D, Chadha VK, Charalambous S, Chin DP, Churchyard G, Daniels C, Dewan P, Ditiu L, Eaton JW, Grant AD, Hippner P, Hosseini M, Mametja D, Pretorius C, Pillay Y, Rade K, Sahu S, Wang L, Houben RMGJ, Kimerling ME, White RG, Vassall Aet al., 2016, Cost-effectiveness and resource implications of aggressive action on tuberculosis in China, India, and South Africa: a combined analysis of nine models, LANCET GLOBAL HEALTH, Vol: 4, Pages: E816-E826, ISSN: 2214-109X

JOURNAL ARTICLE

Arinaminpathy N, Batra D, Khaparde S, Vualnam T, Maheshwari N, Sharma L, Nair SA, Dewan Pet al., 2016, The number of privately treated tuberculosis cases in India: an estimation from drug sales data, LANCET INFECTIOUS DISEASES, Vol: 16, Pages: 1255-1260, ISSN: 1473-3099

JOURNAL ARTICLE

Houben RMGJ, Menzies NA, Sumner T, Huynh GH, Arinaminpathy N, Goldhaber-Fiebert JD, Lin H-H, Wu C-Y, Mandal S, Pandey S, Suen S-C, Bendavid E, Azman AS, Dowdy DW, Bacaer N, Rhines AS, Feldman MW, Handel A, Whalen CC, Chang ST, Wagner BG, Eckhoff PA, Trauer JM, Denholm JT, McBryde ES, Cohen T, Salomon JA, Pretorius C, Lalli M, Eaton JW, Boccia D, Hosseini M, Gomez GB, Sahu S, Daniels C, Ditiu L, Chin DP, Wang L, Chadha VK, Rade K, Hippner P, Charalambous S, Grant AD, Churchyard G, Pillay Y, Mametja LD, Kimerling ME, Vassall A, White RGet al., 2016, Feasibility of achieving the 2025 WHO global tuberculosis targets in South Africa, China, and India: a combined analysis of 11 mathematical models, LANCET GLOBAL HEALTH, Vol: 4, Pages: E806-E815, ISSN: 2214-109X

JOURNAL ARTICLE

Hastings DL, Tokars JI, Aziz IZAMA, Alkhaldi KZ, Bensadek AT, Alraddadi BM, Jokhdar H, Jernigan JA, Garout MA, Tomczyk SM, Oboho LK, Geller AI, Arinaminpathy N, Swerdlow DL, Madani TAet al., 2016, Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014, EMERGING INFECTIOUS DISEASES, Vol: 22, Pages: 794-801, ISSN: 1080-6040

JOURNAL ARTICLE

Nair SA, Raizada N, Sachdeva KS, Denkinger C, Schumacher S, Dewan P, Kulsange S, Boehme C, Paramsivan CN, Arinaminpathy Net al., 2016, Factors Associated with Tuberculosis and Rifampicin-Resistant Tuberculosis amongst Symptomatic Patients in India: A Retrospective Analysis, PLOS ONE, Vol: 11, ISSN: 1932-6203

JOURNAL ARTICLE

Arinaminpathy N, Dowdy D, 2015, Understanding the incremental value of novel diagnostic tests for tuberculosis, NATURE, Vol: 528, Pages: S60-S67, ISSN: 0028-0836

JOURNAL ARTICLE

Sachdeva KS, Raizada N, Gupta RS, Nair SA, Denkinger C, Paramasivan CN, Kulsange S, Thakur R, Dewan P, Boehme C, Arinaminpathy Net al., 2015, The Potential Impact of Up-Front Drug Sensitivity Testing on India's Epidemic of Multi-Drug Resistant Tuberculosis, PLOS ONE, Vol: 10, ISSN: 1932-6203

JOURNAL ARTICLE

Sachdeva KS, Raizada N, Sreenivas A, van't Hoog AH, van den Hof S, Dewan PK, Thakur R, Gupta RS, Kulsange S, Vadera B, Babre A, Gray C, Parmar M, Ghedia M, Ramachandran R, Alavadi U, Arinaminpathy N, Denkinger C, Boehme C, Paramasivan CNet al., 2015, Use of Xpert MTB/RIF in Decentralized Public Health Settings and Its Effect on Pulmonary TB and DR-TB Case Finding in India, PLOS ONE, Vol: 10, ISSN: 1932-6203

JOURNAL ARTICLE

Arinaminpathy N, Cordier-Lassalle T, Lunte K, Dye Cet al., 2015, The Global Drug Facility as an intervention in the market for tuberculosis drugs, BULLETIN OF THE WORLD HEALTH ORGANIZATION, Vol: 93, Pages: 237-248, ISSN: 0042-9686

JOURNAL ARTICLE

Heesterbeek H, Anderson RM, Andreasen V, Bansal S, De Angelis D, Dye C, Eames KTD, Edmunds WJ, Frost SDW, Funk S, Hollingsworth TD, House T, Isham V, Klepac P, Lessler J, Lloyd-Smith JO, Metcalf CJE, Mollison D, Pellis L, Pulliam JRC, Roberts MG, Viboud Cet al., 2015, Modeling infectious disease dynamics in the complex landscape of global health, SCIENCE, Vol: 347, Pages: 1216-U29, ISSN: 0036-8075

JOURNAL ARTICLE

Gog JR, Pellis L, Wood JLN, McLean AR, Arinaminpathy N, Lloyd-Smith JOet al., 2015, Seven challenges in modeling pathogen dynamics within-host and across scales, EPIDEMICS, Vol: 10, Pages: 45-48, ISSN: 1755-4365

JOURNAL ARTICLE

Mandal S, Arinaminpathy N, 2015, Transmission modeling and health systems: the case of TB in India, INTERNATIONAL HEALTH, Vol: 7, Pages: 114-120, ISSN: 1876-3413

JOURNAL ARTICLE

Kouyos RD, Metcalf CJE, Birger R, Klein EY, zur Wiesch PA, Ankomah P, Arinaminpathy N, Bogich TL, Bonhoeffer S, Brower C, Chi-Johnston G, Cohen T, Day T, Greenhouse B, Huijben S, Metlay J, Mideo N, Pollitt LC, Read AF, Smith DL, Standley C, Wale N, Grenfell Bet al., 2014, The path of least resistance: aggressive or moderate treatment?, PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 281, ISSN: 0962-8452

JOURNAL ARTICLE

Faria NR, Rambaut A, Suchard MA, Baele G, Bedford T, Ward MJ, Tatem AJ, Sousa JD, Arinaminpathy N, Pepin J, Posada D, Peeters M, Pybus OG, Lemey Pet al., 2014, The early spread and epidemic ignition of HIV-1 in human populations, SCIENCE, Vol: 346, Pages: 56-61, ISSN: 0036-8075

JOURNAL ARTICLE

Dalziel BD, Huang K, Geoghegan JL, Arinaminpathy N, Dubovi EJ, Grenfell BT, Ellner SP, Holmes EC, Parrish CRet al., 2014, Contact Heterogeneity, Rather Than Transmission Efficiency, Limits the Emergence and Spread of Canine Influenza Virus, PLOS PATHOGENS, Vol: 10, ISSN: 1553-7366

JOURNAL ARTICLE

Faria NR, Rambaut A, Suchard MA, Baele G, Bedford T, Ward MJ, Tatem AJ, Sousa JD, Arinaminpathy N, Pepin J, Posada D, Peeters M, Pybus OG, Lemey Pet al., 2014, Establishment and early spread of the AIDS pandemic, International Workshop on Antiviral Drug Resistance - Meeting the Global Challenge, Publisher: INT MEDICAL PRESS LTD, Pages: A7-A7, ISSN: 1359-6535

CONFERENCE PAPER

Davidovic S, Galesic M, Katsikopoulos K, Arinaminpathy Net al., 2014, Modeling Uncertainty in Banking Networks, 11th International Symposium on Distributed Computing and Artificial Intelligence (DCAI), Publisher: SPRINGER-VERLAG BERLIN, Pages: 107-114, ISSN: 2194-5357

CONFERENCE PAPER

Arinaminpathy N, Cordier-Lassalle T, Vijay A, Dye Cet al., 2013, The Global Drug Facility and its role in the market for tuberculosis drugs, LANCET, Vol: 382, Pages: 1373-1379, ISSN: 0140-6736

JOURNAL ARTICLE

Arinaminpathy N, Lavine JS, Grenfell BT, 2012, Self-boosting vaccines and their implications for herd immunity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 109, Pages: 20154-20159, ISSN: 0027-8424

JOURNAL ARTICLE

Arinaminpathy N, Kapadia S, May RM, 2012, Size and complexity in model financial systems, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 109, Pages: 18338-18343, ISSN: 0027-8424

JOURNAL ARTICLE

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