Summary
Nura is a postdoctor at the Cardiovascular Division, National Heart and Lung Institute.
Nura obtained her BSc (Honorary) in biomedical science from University of Qatar in 2009. Then she worked as a research assistant in the Safallah Medical Genetic Center, Doha, Qatar gaining experience in in recombinant DNA, before joining the Qatar science leadership program (QSLP) in Qatar Foundation and successfully getting a scholarship to Imperial College of London to pursue her studies. She finished her MRes in biomedical research from Imperial College on 1st October 2012 , where she did two research projects . The first project was with Dr.Adrian A Chester, title ‘Biomimetic Matrices for Heart Valve Engineering: Effect of Nanofibrillar Anisotropy on Mechanical Fate’ and the second project was with Professor. Jane A Mitchell with title’ Role of COX-1 and COX-2 in Cytokine Production by Vascular and Gastro-Intestinal Tissue’.
In 2013 she was again awarded a scholarship by QRLP- Qatar Foundation (QF) to do her PhD degree at Imperial College. Working on ' Pharmacology and chemistry of modified prostacyclin drugs; targeting the lung and half-life of the drugs under supervision of Doctor Adrian Chester, Professor Jane Mitchell , Professor Terry D Tetley and Professor Sir. Magdi Yacoub. She finished her PhD in 2016 and was assigned an honorary research officer position at imperial college of London in 2016.
Her main focus is investigating the efficacy of prostacyclin analogue drugs in the pulmonary circulation and how to enhance prostacyclin analogues by using Metal-Organic-Frameworks (MOFs) as a drug delivery system.
Dr.Mohamed is interested in applying nanomedicine to improve treatment strategies for a disease called pulmonary arterial hypertension. Her works yield the development of two novel nanoformulations, an NO-releasing polymer and a sildenafil-loaded metal organic-framework (Sil@nanoMIL-89) . She is also a member of the British Pharmacological Society (BPS) and a member of the Early Career Pharmacologists Advisory Group (ECPAG).
Publications
Journals
Reed DM, Paschalaki KE, Starke RD, et al., 2015, An autologous endothelial cell: peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics, The Faseb Journal, Vol:29, ISSN:0892-6638, Pages:2595-2602
Mitchell JA, Ahmetaj-Shala B, Kirkby NS, et al., 2015, Role of prostacyclin in pulmonary hypertension., Global Cardiology Science and Practice, Vol:2014, ISSN:2305-7823, Pages:382-393
Reed DM, Foldes G, Kirkby NS, et al., 2014, Morphology and vasoactive hormone profiles from endothelial cells derived from stem cells of different sources, Biochemical and Biophysical Research Communications, Vol:455, ISSN:1090-2104, Pages:172-177
George PM, Oliver E, Dorfmuller P, et al., 2014, Evidence for the Involvement of Type I Interferon in Pulmonary Arterial Hypertension, Circulation Research, Vol:114, ISSN:0009-7330, Pages:677-688