Oliver Howes is Group Head and Professor of Molecular Psychiatry. His clinical work is as Consultant Psychiatrist at The Institute of Psychiatry/ Maudsley Hospital.
Contact: tel: +44 (0)20 8383 3298
Mental illnesses are a major cause of ill health and premature death. They account for four of the six leading causes of adult disability in the world and one in every ten hospital beds in the UK is allocated for the treatment of psychotic disorders such as schizophrenia.
“Our research focuses on understanding the causes of mental illnesses and improving their treatment using PET and other functional imaging techniques"
Current work in the group focuses on:
- Understanding the brain changes that lead to the development of psychotic disorders, using multi-modal imaging with PET and MRI
- Examining the effects of cannabis and other drugs on the brain, and the influence of common genetic polymorphisms on brain function
- Determining why some patients respond to treatments and others don’t
- Using novel approaches to diagnosing mental illnesses
- Developing models for future drug development
et al., Neuroinflammation in schizophrenia: meta-analysis of in-vivo microglial imaging studies, Psychological Medicine, ISSN:0033-2917
, OUP accepted manuscript, Schizophrenia Bulletin, ISSN:0586-7614
et al., 2018, Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data, Biological Psychiatry, Vol:84, ISSN:0006-3223, Pages:433-442
et al., Microglia, psychosis and medication; a translational investigation. (De Paola and Howes, Co-Senior authors), BAP 2015 Summer Meeting (Selected for oral presentation)
et al., Microglia, psychosis and medication; a translational investigation. (Selected for oral presentation)., 2015 Summer Meeting - The British Association for Psychopharmacology