Publications
380 results found
Berry M, Chaussabel D, Kon OM, et al., 2009, Distinct and Partially Reciprocal Whole Blood Gene Expression Profiles in Latent and Active Tuberculosis., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X
Salmasi MYBS, Raphael CE, Jepson A, et al., 2009, The Clinical Utility of Post-Bronchoscopy Sputum Samples in Smear Negative PTB., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X
Wickremasinghe MI, Garcia S, O'Donoghue M, et al., 2009, Tuberculin Skin Testing Prior to Anti-TNFα Therapy and Treatment of Latent Tuberculosis Infection., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X
Tan AJ, Kariyawasam HH, Nicholson GC, et al., 2009, Nasal Challenge with Hypertonic Saline (HTS) and Assessment of Neural Reflex Activation (NRA)., AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X
Kariyawasam HH, Nicholson GC, Tan AJ, et al., 2009, Effects of Anti-IL-13 (Novartis QAX576) on Inflammatory Responses Following Nasal Allergen Challenge (NAC), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 179, ISSN: 1073-449X
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- Citations: 2
Hansel TT, Tan AJ, Barnes PJ, et al., 2009, Anticholinergic Bronchodilators, ASTHMA AND COPD: BASIC MECHANISMS AND CLINICAL MANAGEMENT, 2ND EDITION, Editors: Barnes, Drazen, Rennard, Thomson, Publisher: ELSEVIER ACADEMIC PRESS INC, Pages: 615-626, ISBN: 978-0-12-374001-4
Aziz DYA, Munro KJ, O'Donoghue M, et al., 2009, Optimal Timing for Serial Liver Biochemistry Monitoring during Drug Treatment of Tuberculosis, Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Bhowmik A, Ganbari A, Topalidis T, et al., 2009, EUS-FNA in the Diagnosis of Tuberculosis and Sarcoidosis., Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Berry MPR, Chaussabel D, Kon OM, et al., 2008, THE IDENTIFICATION OF DISTINCT GENE EXPRESSION PROFILES IN LATENT AND ACTIVE TUBERCULOSIS, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A63-A63, ISSN: 0040-6376
Connell DW, Lalvani A, O'Donoghue M, et al., 2008, TUBERCULOSIS-ASSOCIATED VITAMIN D DEFICIENCY IS NOT SECONDARY TO MYCOBACTERIAL DISEASE ACTIVITY, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A113-A113, ISSN: 0040-6376
Erin EM, Zacharasiewicz AS, Nicholson GC, et al., 2008, Rapid Effect of Inhaled Ciclesonide in Asthma A Randomized, Placebo-Controlled Study, CHEST, Vol: 134, Pages: 740-745, ISSN: 0012-3692
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- Citations: 32
Message SD, Laza-Stanca V, Mallia P, et al., 2008, Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 105, Pages: 13562-13567, ISSN: 0027-8424
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- Citations: 381
Sathia L, Obiorah I, Taylor G, et al., 2008, Concomitant use of nonnucleoside analogue reverse transcriptase inhibitors and rifampicin in TB/HIV type 1-coinfected patients, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 24, Pages: 897-901, ISSN: 0889-2229
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- Citations: 11
Erin EM, Jenkins GR, Kong OM, et al., 2008, Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants (Retracted article. See vol. 183, pg. 418, 2011), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 177, Pages: 132-141, ISSN: 1073-449X
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- Citations: 21
Kon OM, Hansel TT, Barnes PJ, 2008, Chronic Obstructive Pulmonary Disease, Great Britain, Publisher: Oxford University Press
Kojodjojo P, Wong T, Wright AR, et al., 2008, Pulmonary venous stenosis after treatment for atrial fibrillation., BMJ, Pages: 830-832
Asimacopoulos EP, Berry M, Roesner M, et al., 2007, The diagnostic efficacy of fine needle aspiration utilising cytology and TB culture in tuberculous lymphadenitis, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A81-A82, ISSN: 0040-6376
Berry MPR, Wickremasinghe MIY, Merritt J, et al., 2007, A comparison of interferon-gamma release assays and diagnostic algorithms for latent tuberculosis, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A81-A81, ISSN: 0040-6376
Toma TP, Kon OM, Oldfield W, et al., 2007, Reduction of persistent air leak with endoscopic valve implants, THORAX, Vol: 62, Pages: 830-833, ISSN: 0040-6376
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- Citations: 38
Fritscher-Ravens A, Ghanbari A, Pelling M, et al., 2007, Non malignant mediastinal adenopathy: Can EUS-FNA differentiate tuberculosis and sarcoidosis?, Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, Publisher: MOSBY-ELSEVIER, Pages: AB119-AB119, ISSN: 0016-5107
Erin EM, Kon OM, Barnes PJ, et al., 2007, Anti-tumor necrosis factor-α in asthma, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 175, Pages: 288-289, ISSN: 1073-449X
Erin EM, Kon OM, Barnes PJ, et al., 2007, Study of infliximab treatment in asthma - From the authors, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 175, Pages: 196-197, ISSN: 1073-449X
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- Citations: 1
Nicholson GC, Tennant RC, Carpenter DC, et al., 2007, A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist, Pulmonary Pharmacology and Therapeutics, Vol: 20, Pages: 52-59, ISSN: 1094-5539
Boyton RJ, Altmann DM, Wright A, et al., 2007, Pulmonary infection with <i>Cryptococcus neoformans</i> in the face of underlying sarcoidosis, RESPIRATION, Vol: 74, Pages: 462-466, ISSN: 0025-7931
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- Citations: 8
Erin EM, Leaker BR, Nicholson GC, et al., 2006, The effects of a monoclonal antibody directed against tumor necrosis factor-α in asthma (Retracted article. See vol. 183, pg. 418, 2011), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 174, Pages: 753-762, ISSN: 1073-449X
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- Citations: 220
Boyton RJ, Reynolds C, Wahid FN, et al., 2006, IFNγ and CXCR-1 gene polymorphisms in idiopathic bronchiectasis, TISSUE ANTIGENS, Vol: 68, Pages: 325-330, ISSN: 0001-2815
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- Citations: 17
Mallia P, Message SD, Kebadze T, et al., 2006, An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study, Respiratory Research, Vol: 7, ISSN: 1465-993X
BackgroundAcute exacerbations of COPD are a major cause of morbidity, mortality and hospitalisation. Respiratory viruses are associated with the majority of exacerbations but a causal relationship has not been demonstrated and the mechanisms of virus-induced exacerbations are poorly understood. Development of a human experimental model would provide evidence of causation and would greatly facilitate understanding mechanisms, but no such model exists.MethodsWe aimed to evaluate the feasibility of developing an experimental model of rhinovirus induced COPD exacerbations and to assess safety of rhinovirus infection in COPD patients. We carried out a pilot virus dose escalating study to assess the minimum dose of rhinovirus 16 required to induce experimental rhinovirus infection in subjects with COPD (GOLD stage II). Outcomes were assessed by monitoring of upper and lower respiratory tract symptoms, lung function, and virus replication and inflammatory responses in nasal lavage.ResultsAll 4 subjects developed symptomatic colds with the lowest dose of virus tested, associated with evidence of viral replication and increased pro-inflammatory cytokines in nasal lavage. These were accompanied by significant increases in lower respiratory tract symptoms and reductions in PEF and FEV1. There were no severe exacerbations or other adverse events.ConclusionLow dose experimental rhinovirus infection in patients with COPD induces symptoms and lung function changes typical of an acute exacerbation of COPD, appears safe, and provides preliminary evidence of causation.
Cetti EJ, Polkey MI, Kon OM, et al., 2006, Bronchosocpic Techiques for treating emphysema, Clinical Pulmonary Medicine, Vol: 13, Pages: 263-270
Sukkar MB, Xie S, Khorasani NM, et al., 2006, Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 118, Pages: 641-648, ISSN: 0091-6749
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- Citations: 117
Contoli M, Message SD, Laza-Stanca V, et al., 2006, Role of deficient type III interferon-λ production in asthma exacerbations, NATURE MEDICINE, Vol: 12, Pages: 1023-1026, ISSN: 1078-8956
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- Citations: 799
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