Imperial College London

ProfessorPhilipAshton-Rickardt

Faculty of MedicineDepartment of Medicine

Chair in Immunology
 
 
 
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Contact

 

+44 (0)20 7594 2762p.ashton-rickardt Website

 
 
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Location

 

258Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Memory T lymphocytes form the basis of immunological memory through their ability to rapidly eliminate invaders. We work on understanding the molecular basis of how memory T lymphocytes develop and how they are maintained.   We hope that our research will lead to an improvement in vaccination through the induction of potent T cell memory.

Publications

Journals

Ashton-Rickardt PG, 2016, Mitochondria Apply the Brake to Viral Immunity, Cell Metabolism, Vol:23, ISSN:1932-7420, Pages:967-968

Ashton-Rickardt PG, 2015, A Memory of Rejection?, American Journal of Transplantation, Vol:15, ISSN:1600-6135, Pages:13-14

Okoye I, Wang L, Pallmer K, et al., 2015, The protein LEM promotes CD8(+) T cell immunity through effects on mitochondrial respiration, Science, Vol:348, ISSN:0036-8075, Pages:995-1001

Dev A, Byrne SM, Verma R, et al., 2014, Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins., J Exp Med, Vol:211

Kim M-S, Buisson LA, Heathcote DA, et al., 2014, Approaches to design non-covalent inhibitors for human granzyme B (hGrB), Organic & Biomolecular Chemistry, Vol:12, ISSN:1477-0520, Pages:8952-8965

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