Imperial College London

ProfessorPaulElliott

Faculty of MedicineSchool of Public Health

Chair in Epidemiology and Public Health Medicine
 
 
 
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Contact

 

+44 (0)20 7594 3328p.elliott Website

 
 
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Assistant

 

Miss Jennifer Wells +44 (0)20 7594 3328

 
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Location

 

154Norfolk PlaceSt Mary's Campus

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Summary

 

Summary

Professor Paul Elliott, MBBS, PhD, FMedSci, trained in clinical medicine and epidemiology as a Wellcome Trust Clinical Fellow at St Mary's Hospital London and the London School of Hygiene & Tropical Medicine. He studied for his PhD in Epidemiology on the INTERSALT Study under the mentorship of Professor Geoffrey Rose. He remained at the London School working as a lecturer, and subsequently as senior lecturer and reader in epidemiology before being appointed as Head of the Environmental Epidemiology Unit at LSHTM 1990. In 1995 he was appointed to the Chair in Epidemiology and Public Health Medicine at Imperial College London. Since then he has managed the transformation of the Department of Public Health into the present Department of Epidemiology and Biostatistics in the School of Public Health. The Department has expanded significantly during recent years to encompass a wide-ranging programme of health research and extensive collaborations with national and international research groups and hosting both honorary and visiting staff. Paul Elliott is also Director of the MRC-PHE Centre for Environment and Health, which was launched in 2009 as a joint collaboration with King's College London and forms a major part of the Department and includes the Small Area Health Statistics Unit (SAHSU). He is also an honorary consultant in public health medicine in the Directorate of Primary Care and Public Health of the Imperial College Healthcare NHS Trust and the academic lead for the Informatics & Biobanking research theme of the Imperial NIHR Biomedical Research Centre. He is the current Director of Information Governance for the Imperial College Academic Health Sciences Centre's (AHSC) Director.

Leadership roles :
Head of Department of Epidemiology and Biostatistics
Director of MRC-PHE Centre for Environment and Health
Director of Small Area Health Statistics Unit (SAHSU)
Co-Director of MRC-NIHR National Phenome Centre
Deputy Director of HPRU on the Health Impact of Environmental Hazards
Emeritus NIHR Senior Investigator
Visiting Professor Nanyang Technological University Lee Kong Chian School of Medicine (since 2016)
ACCEA platinum award holder (original award 2008)
ISI Highly cited researcher in genomics 2014&2015
H-index 94

Key Research Interests:
Environmental epidemiology and small area health statistics
Genetic and molecular epidemiology, gene-environment interactions
Nutritional epidemiology - focus on diet, high blood pressure and cardiovascular disease
Population cohort studies and biobankiing
Non-ionising radiation and health

Key Research projects:

  • The MRC-PHE Centre for Environment and Health was created in 2009 and has established a centre for excellence in research and postgraduate training in the field of environment and health. Research themes include Exposome and Health; Air Pollution, Noise and Health; Small Area Health Studies. The Centre includes the Small Area Health Statistics Unit (SAHSU). The Centre hosts postgraduate students and fellows funded by its PhD studentship and early career fellowship schemes. 
    MRC-PHE Centre for Environment and Health
    Small Area Health Statistics Unit
  • AIRWAVE health monitoring study - on long-term health in relation to the use of the TETRA communication system by police force personnel. Funding: Home Office. The baseline survey took place between 2004-2015, with extensive data collection by a computerised questionnaire, a range of physical measurements, and collection of a 50ml non-fasting blood sample. A programme of follow-up health-screens is currently open to participants at selected locations across the country.
    Airwave study
  • UK COSMOS - International cohort study of mobile phones and health with data on >100,000 UK mobile phone users, part of a long-term cohort study with participants recruited in 3 other European countries (Denmark, Sweden, Finland). Funding: Department of Health.
    UK COSMOS
  •  SCAMP Study - cohort study which which is following several thousand secondary school pupils across London from year 7 through to year 9. The aim of this study is to investigate whether children’s use of mobile phones affects their cognitive and behavioural development
    SCAMP study 
  •  AIRLESS study - NERC-funded project on the Effects of air pollution on cardiopulmonary disease in urban and peri-urban residents in Beijing. Project led by Prof Frank Kelly (King's College London).  
  •  Imperial College Dementia Research Institute Foundation Award. Director Prof Paul Matthews. Funding from the MRC Alzheimer's Society and Alzheimer's Research UK to set up a new research institute. Lead for the programme on molecular epidemiology in collaboration with Prof Elaine Holmes.
  • NIHR Health Protection Research Unit on Health Impacts of Environmental Hazards. Director Prof Frank Kelly, King's College London. PI for Theme 2 Modes of Toxicity project on Approaches to the Analysis of Serum and Urinary Metabolome
    NIHR HPRU Health Impacts of Environmental Hazards
  •  INTERMAP international Collaborative study of dietary macro-and micro-nutrients and blood pressure  and health. Blood pressure, dietary and urinary, anthropometric and questionnaire data were collected from 4680 men and women (40-59 years of age) recruited from 17 populations across 4 countries (Japan, China, U.K., U.S.A.). The INTERMAP data resource is currently being analysed for U.S. National Institutes of Health funded projects on: 1) Metabolomics measured urinary metabolites, diet and blood pressure and 2) Metabolic pathways underlying the contrasting sodium-blood pressure and DASH-OmniHeart-blood pressure relationships
    INTERMAP study
  • U.S. National Institutes of Health funded project on Metabolomic signatures of coronary artery disease (CAD) associated genotypes in collaboration with Dr David Herrington (PI at Wake Forest University)
  • HELIOS study - epidemiological cohort study to better predict and prevent the development of chronic conditions. A collaboration with Nanyang Technological University- Lee Kong Chian School of Medicine, and the National Healthcare Group Singapore. 

    Resource Development
  • MRC-NIHR National Phenome Centre - a national facility that provides world-leading capacity in large-scale metabolic phenotyping for academic researchers. Director Prof Jeremy Nicholson. Role: Co-Director
    MRC-NIHR National Phenome Centre
  •  UK MED-BIO Medical Bioinformatics partnership: aggregation, integration, visualisation and analysis of large, complex data. MRC-funded initiative to build high performance computing and IT resource to support the integration, processing and storage of large scale biomedical ("big") data
    UK MED-BIO
  • Imperial College London Biomedical Research Centre Informatics & Biobanking research theme. The theme aims to provide world-leading health analytics and patient, tissue and population resources, linked to deep phenotypic information, omics and clinical outcomes, forming the basis for recruitment into experimental medicine studies, prognostic research and biomarker discovery, validation and qualification across the BRC.
    NIHR Imperial College Biomedical Research Centre
  • EU HORIZON 2020 PhenoMeNal project is developing a comprehensive and standardised e-infrastructure that supports the data processing and analysis pipelines for molecular phenotype data generated by metabolomics applications.
    PhenoMeNal
  •  Imperial College BioResource is contributing to a National Institute for Health Research (NIHR) initiative to facilitate biomedical research in industry, academia, and the NHS. The main objective is to create a resource of healthy volunteers and patients from the general population who are willing to be approached to take part in research studies investigating the links between genes, the environment, health, and disease
    Imperial Population BioResource

Research collaboration

AIRLESS - Prof Rod Jones (Cambridge), Prof Tong Zhu (Peking University), Prof Junfeng Zhang (Duke University), Prof Meiping Zhao and Yangfeng Wu (Peking University)

AIRWAVE - Prof John Gallacher (DPUK)

COMBI-BIO - D Herrington (Wake Forest University), P Greenland (Northwestern University), R Tracy (University of Vermont), E Evangelou (Ioannina University), C Gieger (Helmholtz Munich), A Deghan (Erasmus)

ICBP consortium M Caulfield, P Munroe, Helen Warren, Michael Barnes (QMUL)

INTERMAP - J Stamler, A Dyer, L van Horn (Northwestern University), M Daviglus (University of Illinois), J Molitor (University of Oregon), J Nicholson, E Holmes (Imperial College London)

LOLIPOP (London Life Sciences Prospective Population Cohort) Study - PI: Kooner. http://www.lolipopstudy.org/

Northern Finland Birth Cohorts - PI: Jarvelin

MRC-PHE Centre - Prof Frank Kelly (King's College London)

UK MED-BIO - J Griffin (MRC Cambridge), R Lyons (CIPHER Swansea)

Teaching:

Recent lectures contributed to these courses and modules at Imperial:

BSc in Global Health
MBBS Epidemiology in Practice
MSc in Epidemiology Principles of Global Epidemiology module and Social Epidemiology module
Masters in Public Health
Short courses including : International Nutritional Epidemiology (course director: Prof Elio Riboli); Global Health (course director Dr Daniela Fecht); Stat XP (course director Dr Marc Chadeau).

Postgraduate PhD Student Supervision:

Goncalo de Santos Correia Novel computational and chemometric methods for modelling cardiovascular metabolic phenotypic data. Joint supervisors: Prof Elaine Holmes, Paul Elliott

Robbie Parks Forecasting seasonal mortality and estimating the effect of various climate change scenarios ISSF funded studentship. Joint supervision: Prof Majid Ezzati, Ralph Toumi, Paul Elliott.

Javiera Farrido Unified approaches to cross-omic profiling. Joint supervision: Dr Marc Chadeau, Paul Elliott.

Elzbieta Lauzikaite Development and application of novel analytical methods for metabolite structure elucidation. Joint supervision: Dr Toby Athersuch, Dr Isabel Garcia-Perez , Paul Elliott, Ioanna Tzoulaki

Arinbjorn Kolbeinsson Using deep learning to predict health outcomes based on MR imaging and other high dimensional data Joint supervision: Dr Ioanna Tzoulaki, Dr Korbinian Strimmer, Paul Elliott .                        

Post-doctoral fellows under supervision:

Antonio Berlanga-Taylor, PhD MRC Intermediate Research Fellowship in Computational Biology award working on GWAS and post-GWAS characterisation of inflammation and disease: integrative analysis of genomes and phenomes in large epidemiological studies. Appointed October 2015.

Oliver Robinson, PhD MRC-PHE Centre for Environment and Health Early Career Research Fellowship working on Assessing the impact of the early life exposome on child growth and adiposity. Appointed April 2016. Primary supervisor Prof Paolo Vineis.

Deborah Schneider-Luftman, PhD UK MED-BIO Intermediate Research Fellowship award working on Multi-omics and epidemiologic data integration for disease mechanism research. Appointed June 2017.

Dr Xie Wuxiang Newton International Research Fellowship working on project on Dose–response relationship between air pollution and cardiovascular disease in Beijing. 1 Mar, 2016 – 28 Feb 2018.

Mentoring: academic mentor for the Academy of Medical Sciences mentorship scheme since 2012. Currently providing advice to 4 mid-career clinical scientists. 

Selected Publications

Journal Articles

Elliott P, Posma JM, Chan Q, et al., 2015, Urinary metabolic signatures of human adiposity, Science Translational Medicine, Vol:7, ISSN:1946-6234

More Publications