Imperial College London

ProfessorPaulElliott

Faculty of MedicineSchool of Public Health

Chair in Epidemiology and Public Health Medicine
 
 
 
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Contact

 

+44 (0)20 7594 3328p.elliott Website

 
 
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Assistant

 

Miss Jennifer Wells +44 (0)20 7594 3328

 
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Location

 

154Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Tzoulaki:2018:10.1007/s11906-018-0877-8,
author = {Tzoulaki, I and Iliou, A and Mikros, E and Elliott, P},
doi = {10.1007/s11906-018-0877-8},
journal = {Current Hypertension Reports},
title = {An overview of metabolic phenotyping in blood pressure research},
url = {http://dx.doi.org/10.1007/s11906-018-0877-8},
volume = {20},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Purpose of the ReviewThis review presents the analytical techniques, processing and analytical steps used in metabolomics phenotyping studies, as well as the main results from epidemiological studies on the associations between metabolites and high blood pressure.Recent FindingsA variety of metabolomic approaches have been applied to a range of epidemiological studies to uncover the pathophysiology of high blood pressure. Several pathways have been suggested in relation to blood pressure including the possible role of the gut microflora, inflammatory, oxidative stress, and lipid pathways. Metabolic changes have also been identified associated with blood pressure lowering effects of diets high in fruits and vegetables and low in meat intake. However, the current body of literature on metabolic profiling and blood pressure is still in its infancy, not fully consistent and requires careful interpretation.SummaryMetabolic phenotyping is a promising approach to uncover metabolic pathways associated with high blood pressure and throw light into the complex pathophysiology of hypertension.
AU - Tzoulaki,I
AU - Iliou,A
AU - Mikros,E
AU - Elliott,P
DO - 10.1007/s11906-018-0877-8
PY - 2018///
SN - 1522-6417
TI - An overview of metabolic phenotyping in blood pressure research
T2 - Current Hypertension Reports
UR - http://dx.doi.org/10.1007/s11906-018-0877-8
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438368200002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/62981
VL - 20
ER -