Imperial College London

ProfessorPaulFarrell

Faculty of MedicineDepartment of Infectious Disease

Professor of Tumour Virology
 
 
 
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Contact

 

+44 (0)20 7594 2005p.farrell Website

 
 
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Location

 

Section of VirologyNorfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gregorovic:2015:10.1128/JVI.01873-15,
author = {Gregorovic, G and Boulden, EA and Bosshard, R and Karstegl, CE and Skalsky, R and Cullen, BR and Gujer, C and Rämer, P and Münz, C and Farrell, PJ},
doi = {10.1128/JVI.01873-15},
journal = {Journal of Virology},
pages = {1171--11714},
title = {Epstein-Barr viruses deficient in EBER RNAs give higher LMP2 RNA expression in lymphoblastoid cell lines and efficiently establish persistent infection in humanized mice.},
url = {http://dx.doi.org/10.1128/JVI.01873-15},
volume = {89},
year = {2015}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Functions of EBER RNAs were tested in lymphoblastoid cell lines containing EBER mutants of Epstein-Barr Virus (EBV). Binding of EBER1 to RPL22 was confirmed. Deletion of EBER1 or EBER2 correlated with increased cytoplasmic EBV LMP2 RNA and with small effects on specific cellular miRNA levels but protein levels of LMP1 and LMP2A were not affected. Wild type and EBER deletion EBV had approximately equal ability to infect immunodeficient mice reconstituted with a human haematopoietic system.
AU - Gregorovic,G
AU - Boulden,EA
AU - Bosshard,R
AU - Karstegl,CE
AU - Skalsky,R
AU - Cullen,BR
AU - Gujer,C
AU - Rämer,P
AU - Münz,C
AU - Farrell,PJ
DO - 10.1128/JVI.01873-15
EP - 11714
PY - 2015///
SN - 1098-5514
SP - 1171
TI - Epstein-Barr viruses deficient in EBER RNAs give higher LMP2 RNA expression in lymphoblastoid cell lines and efficiently establish persistent infection in humanized mice.
T2 - Journal of Virology
UR - http://dx.doi.org/10.1128/JVI.01873-15
UR - http://hdl.handle.net/10044/1/26502
VL - 89
ER -