Imperial College London
Alternate

ProfessorPatriciaHunt

Faculty of Natural Sciences, Department of Chemistry

Visiting Professor
 
 
 
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Contact

 

p.hunt Website

 
 
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Location

 

Molecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Zoeller:2023:jendso/bvad107,
author = {Zoeller, RT and Birnbaum, LS and Collins, TJ and Heindel, J and Hunt, PA and Iguchi, T and Kortenkamp, A and Myers, JP and Vom, Saal FS and Sonnenschein, C and Soto, AM},
doi = {jendso/bvad107},
journal = {J Endocr Soc},
title = {European Medicines Agency Conflicts With the European Food Safety Authority (EFSA) on Bisphenol A Regulation.},
url = {http://dx.doi.org/10.1210/jendso/bvad107},
volume = {7},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The European Food Safety Authority (EFSA) has revised their estimate of the toxicity of bisphenol A (BPA) and, as a result, have recommended reducing the tolerable daily intake (TDI) by 20 000-fold. This would essentially ban the use of BPA in food packaging such as can liners, plastic food containers, and in consumer products. To come to this conclusion, EFSA used a systematic approach according to a pre-established protocol and included all guideline and nonguideline studies in their analysis. They found that Th-17 immune cells increased with very low exposure to BPA and used this endpoint to revise the TDI to be human health protective. A number of regulatory agencies including the European Medicines Agency (EMA) have written formal disagreements with several elements of EFSA's proposal. The European Commission will now decide whether to accept EFSA's recommendation over the objections of EMA. If the Commission accepts EFSA's recommendation, it will be a landmark action using knowledge acquired through independent scientific studies focused on biomarkers of chronic disease to protect human health. The goal of this Perspective is to clearly articulate the monumental nature of this debate and decision and to explain what is at stake. Our perspective is that the weight of evidence clearly supports EFSA's proposal to reduce the TDI by 20 000-fold.
AU  - Zoeller,RT
AU  - Birnbaum,LS
AU  - Collins,TJ
AU  - Heindel,J
AU  - Hunt,PA
AU  - Iguchi,T
AU  - Kortenkamp,A
AU  - Myers,JP
AU  - Vom,Saal FS
AU  - Sonnenschein,C
AU  - Soto,AM
DO  - jendso/bvad107
PY  - 2023///
TI  - European Medicines Agency Conflicts With the European Food Safety Authority (EFSA) on Bisphenol A Regulation.
T2  - J Endocr Soc
UR  - http://dx.doi.org/10.1210/jendso/bvad107
UR  - https://www.ncbi.nlm.nih.gov/pubmed/37873497
VL  - 7
ER  -
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