Imperial College London
Dr Peter Jenkins

DrPeterJenkins

Faculty of Medicine, Department of Brain Sciences

Honorary Clinical Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 8064p.jenkins Website

 
 
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Location

 

C3NL LaboratoryBurlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jenkins:2009:10.7861/clinmedicine.9-5-431,
author = {Jenkins, PO and Sultanzadeh, J and Bhagwat, M and Jenkins, PF},
doi = {10.7861/clinmedicine.9-5-431},
journal = {Clinical Medicine, Journal of the Royal College of Physicians of London},
pages = {432--435},
title = {Should thrombolysis have a greater role in the management of pulmonary embolism?},
url = {http://dx.doi.org/10.7861/clinmedicine.9-5-431},
volume = {9},
year = {2009}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Pulmonary embolism (PE) continues to be associated with significant mortality despite advances in the diagnostic techniques available for its detection. Anticoagulation remains standard treatment in PE although there is a consensus view that 'step-up' to thrombolytic therapy in addition to anticoagulation is indicated in those patients who are systemically shocked at presentation - a group defined as having suffered 'massive pulmonary embolism'. Considerable research has been directed at attempting to identify further groups of patients with PE who are at high risk of morbidity and mortality - notably those who are labelled as having suffered 'sub-massive pulmonary embolism' where this is defined as the presence of right-heart strain in the absence of systemic shock. In particular, the potential benefit of extending thrombolytic therapy to include those patients with sub-massive PE has been the subject of much enquiry and debate. This review examines the evidence for thrombolytic therapy and explores the potential for risk stratification in PE. © Royal College of Physicians, 2009. All rights reserved.
AU  - Jenkins,PO
AU  - Sultanzadeh,J
AU  - Bhagwat,M
AU  - Jenkins,PF
DO  - 10.7861/clinmedicine.9-5-431
EP  - 435
PY  - 2009///
SN  - 1470-2118
SP  - 432
TI  - Should thrombolysis have a greater role in the management of pulmonary embolism?
T2  - Clinical Medicine, Journal of the Royal College of Physicians of London
UR  - http://dx.doi.org/10.7861/clinmedicine.9-5-431
VL  - 9
ER  -
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