Imperial College London
Alternate

Dr Peter Kelleher

Faculty of Medicine, Department of Infectious Disease

Reader in Immunology
 
 
 
//

Contact

 

+44 (0)20 3315 8251p.kelleher

 
 
//

Location

 

J.2.10Chelsea and Westminster HospitalChelsea and Westminster Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Metcalf:2013:10.1079/PAVSNNR20128019,
author = {Metcalf, R and Kelleher, P},
doi = {10.1079/PAVSNNR20128019},
journal = {CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources},
title = {TB vaccines in the era of HIV: New developments},
url = {http://dx.doi.org/10.1079/PAVSNNR20128019},
volume = {8},
year = {2013}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Mycobacterium tuberculosis (M.tb) infection is a global problem, which is exacerbated by human immunodeficiency virus-1 (HIV-1) co-infection. Despite the use of the Bacillus Calmette-Guérin (BCG) vaccine for over a century, it is evident that a new vaccine is needed because of its limitations in efficacy against tuberculosis (TB) and concerns about its safety in HIV-1-infected individuals. The complications of immune deficiency in HIV-1 patients must be taken into account when developing a vaccine suitable for this population. Although there have been no new vaccines since BCG, there are a number of vaccines in the pipeline, some of which have undergone safety and efficacy tests in clinical trials in HIV-1-infected patients. In this review, we will summarize the interactions between HIV-1 and TB and their effects on the immune system and review the development of new TB vaccines and their use in patients with HIV-1 infection. © 2013 CAB International.
AU  - Metcalf,R
AU  - Kelleher,P
DO  - 10.1079/PAVSNNR20128019
PY  - 2013///
TI  - TB vaccines in the era of HIV: New developments
T2  - CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources
UR  - http://dx.doi.org/10.1079/PAVSNNR20128019
VL  - 8
ER  -
Download