Imperial College London
Alternate

ProfessorPaulLangford

Faculty of Medicine, Department of Infectious Disease

Professor of Paediatric Infectious Diseases
 
 
 
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Contact

 

+44 (0)20 7594 3359p.langford Website

 
 
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Location

 

236Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Stringer:2021:10.1016/j.vetmic.2021.109021,
author = {Stringer, O and Bosse, J and Lacouture, S and Gottschalk, M and Fodor, L and Angen, Ø and Velazquez, E and Penny, P and Lei, L and Langford, P and Li, Y},
doi = {10.1016/j.vetmic.2021.109021},
journal = {Veterinary Microbiology},
title = {Proposal of Actinobacillus pleuropneumoniae serovar 19, and reformulation of previous multiplex PCRs for capsule-specific typing of all known serovars},
url = {http://dx.doi.org/10.1016/j.vetmic.2021.109021},
volume = {255},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Two serologically and molecularly non-typeable isolates of the porcine lung pathogen Actinobacillus pleuropneumoniae have been identified from diseased swine in two different continents. Genome sequencing was carried out to identify their diagnostically relevant genotypes. Both isolates are biovar 1 and encode genes for production of ApxIV and ApxII (apxIICA structural genes, and apxIBD export genes). They both possess the same novel type II capsule locus (most similar to serovar 1, but with two capsule genes not previously found in A. pleuropneumoniae) but differ in their O-Ag loci. Strain 7213384-1 from Denmark, which we propose as the reference strain for serovar 19, has a serogroup 3/6/8/15 O-Ag locus; the Canadian isolate A08-13 has a serogroup 4/7 O-Ag locus.  We have expanded the second of our two previously described A. pleuropneumoniae mPCRs to include capsule gene-specific primers for definitive detection of serovars 13-14 and 16-19.
AU  - Stringer,O
AU  - Bosse,J
AU  - Lacouture,S
AU  - Gottschalk,M
AU  - Fodor,L
AU  - Angen,Ø
AU  - Velazquez,E
AU  - Penny,P
AU  - Lei,L
AU  - Langford,P
AU  - Li,Y
DO  - 10.1016/j.vetmic.2021.109021
PY  - 2021///
SN  - 0378-1135
TI  - Proposal of Actinobacillus pleuropneumoniae serovar 19, and reformulation of previous multiplex PCRs for capsule-specific typing of all known serovars
T2  - Veterinary Microbiology
UR  - http://dx.doi.org/10.1016/j.vetmic.2021.109021
UR  - http://hdl.handle.net/10044/1/86195
VL  - 255
ER  -
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