Publications
669 results found
Nihoyannopoulos P, Isaacs J, Bidstrup B, et al., 1998, Right atrial thrombus mimicking myxoma, J Cardiovasc Ultrason, Vol: 7
Cokkinos P, Kurbaan AA, Nihoyannopoulos P, 1998, Dobutamine stress echocardiography, Br J Cardiol, Vol: 5
Rallidis L, Cokkinos P, Tousoulis D, et al., 1997, Comparison of dobutamine and treadmill exercise echocardiography in inducing ischemia in patients with coronary artery disease, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 30, Pages: 1660-1668, ISSN: 0735-1097
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- Citations: 59
Clapp BR, Ratnatunga CP, Nihoyannpoulos P, 1997, An unusual aorto-pulmonary communication secondary to syphilitic aortitis., Int J Cardiol, Vol: 62, Pages: 155-159, ISSN: 0167-5273
With the advent of antibiotics syphilis and its complications appear to have been declining as an important cause of cardiovascular disease. We describe a patient with an unusual aorto-pulmonary communication secondary to syphilitic aortitis. The case illustrates the difficulty in defining the anatomy of this rare association preoperatively. The reason for the rarity of this manifestation is discussed and finally doubt is cast upon the assumption that cardiovascular syphilis is of only historical interest.
Moyssakis IE, Rallidis LS, Guida GF, et al., 1997, Incidence and evolution of carcinoid syndrome in the heart., J Heart Valve Dis, Vol: 6, Pages: 625-630, ISSN: 0966-8519
BACKGROUND AND AIMS OF THE STUDY: Carcinoid syndrome originates from carcinoid tumors localized in the gastrointestinal system, pancreas, biliary vessels, bronchi, ovaries and testes. The condition is characterized by flushing, telangiectasias, diarrhea, bronchoconstriction and cardiac involvement, while cardiac lesions may occur in 50% of patients. This study aimed to investigate-non-invasively-the frequency, severity and evolution of carcinoid heart involvement. METHODS AND RESULTS: Among 87 patients with carcinoid syndrome undergoing routine echocardiography, 39 (45%) had cardiac involvement; 36 of these had thickened, shortened, immobile tricuspid leaflets. Tricuspid regurgitation was present in all 36, it was moderate or severe in 22. Pressure half-time rose to 117 +/- 35 ms, implying mild tricuspid stenosis. The pulmonary valve was also thickened, retracted and immobile with stenotic appearance in 19 patients; regurgitation was present in 16, and mild in 11. Nine patients had pericardial effusion. Of 39 patients with cardiac lesions, 18 had at least one follow up study within 16 +/- 7 months; in 15 cases the valve lesions deteriorated. Tricuspid regurgitation became more severe in six and pressure half-time rose from 107 +/- 46 to 132 +/- 50 ms. Pulmonary regurgitation deteriorated in two, while three patients had new pulmonary valve involvement. The peak gradient across the pulmonary valve increased from 18 +/- 7 to 25 +/- 9 mmHg. Twenty-two patients without heart involvement in the first examination had a follow up study (19 +/- 5 months) during which seven developed valvular lesions, with four moderate and three mild tricuspid regurgitation; mild stenosis was present in all cases. Two patients with mild tricuspid regurgitation had mild mixed pulmonary valve involvement, while of those with moderate tricuspid regurgitation, one also had moderate pulmonary stenosis with mild regurgitation. Five patients with both tricuspid and pulmonary valve diseases had int
Jucquois I, Nihoyannopoulos P, DHondt AM, et al., 1997, Detection of myocardial perfusion abnormalities by myocardial contrast echocardiography with NC100100 and transient response second harmonic imaging in patients with previous myocardial infarction: comparison with Tc-99m MIBI single photon emission computed tomography, CIRCULATION, Vol: 96, Pages: 818-818, ISSN: 0009-7322
Clesham GJ, Vigushin DM, Hawkins PN, et al., 1997, Echocardiographic assessment of cardiac involvement in systemic AL amyloidosis in relation to whole body amyloid load measured by serum amyloid P component (SAP) clearance., Am J Cardiol, Vol: 80, Pages: 1104-1108, ISSN: 0002-9149
The severity of cardiac infiltration in AL amyloidosis is unrelated to whole body amyloid load as measured by serum amyloid P (SAP) tracer studies. Radiolabeled SAP and echocardiography permit identification of patients with severe cardiac disease with a low whole body load who may be the best candidates for transplantation.
Clesham GJ, Vigushin DM, Hawkins PN, et al., 1997, Echocardiographic assessment of cardiac involvement in systemic AL amyloidosis in relation to whole body amyloid load measured by serum amyloid P component (SAP) clearance, AMERICAN JOURNAL OF CARDIOLOGY, Vol: 80, Pages: 1104-&, ISSN: 0002-9149
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- Citations: 9
Stangou AJ, Hawkins PN, Heaton ND, et al., 1997, Progressive restrictive cardiomyopathy following orthotopic liver transplantation for familial amyloid polyneuropathy., HEPATOLOGY, Vol: 26, Pages: 869-869, ISSN: 0270-9139
Tsoukas A, Ikonomidis I, Cokkinos P, et al., 1997, Significance of persistent left ventricular dysfunction during recovery after dobutamine stress echocardiography, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 30, Pages: 621-626, ISSN: 0735-1097
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- Citations: 35
Senior R, Kenny A, Nihoyannopoulos P, 1997, Stress echocardiography for assessing myocardial ischaemia and viable myocardium., Heart, Vol: 78 Suppl 1, Pages: 12-18, ISSN: 1355-6037
Kassimatis A, Tsoukas A, Ikonomidis I, et al., 1997, Routine arterial oxygen saturation monitoring is not necessary during transesophageal echocardiography, CLINICAL CARDIOLOGY, Vol: 20, Pages: 547-552, ISSN: 0160-9289
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- Citations: 5
Rallidis L, Tousoulis D, Cokkinos P, et al., 1997, Dobutamine stress echo test results: Relationship to coronary stenosis severity, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 29, Pages: 2583-2583, ISSN: 0735-1097
Rallidis LS, Nihoyannopoulos P, Thompson GR, 1997, Diagnosis and management of aortic stenosis in homozygous familial hypercholesterolaemia, Hellenic Journal of Cardiology, Vol: 38, Pages: 316-320, ISSN: 1011-7970
We describe a young woman with homozygous familial hypercholesterolaemia complicated by aortic stenosis, supravalvular aortic atheroma and coronary artery disease. The association of these disorders is common in homozygotes and usually requires surgical intervention with a high operative risk. Our patient underwent successfully widening of the aortic root, aortic valve replacement and aortocoronary bypass grafting, but 2 out of 4 similarly treated patients died.
Tsoukas AS, Kassimatis AS, Ikonomidis IG, et al., 1997, Echocardiographic assessment of cardiac dimensions in patients with increased cardiothoracic ratio, Hellenic Journal of Cardiology, Vol: 38, Pages: 305-309, ISSN: 1011-7970
Introduction: Measurement of cardiothoracic ratio (CTR) on chest X-ray is routinely used as an index of cardiomegaly. Echocardiography is currently extensively used for assessment of cardiac anatomy and chamber dimensions. However, CTR remains the first choice measurement for an overall impression of cardiac size in clinical practice because of its simplicity and wide understanding. Methods: We studied 73 consecutive patients referred for echocardiographic assessment of the cardiac anatomy following the detection of increased cardiothoracic ratio during routine postero-anterior chest X- ray. The cardiac chambers dimensions, the ventricular septum and the posterior left ventricular wall thickness and the presence of pericardial effusion were evaluated. Results: Echocardiography was normal in 30 patients (41%) while 7 patients (9%) had pericardial effusion with normal cardiac dimensions. In 25 patients (34%) dilatation of left ventricle with or without left atrial enlargement was observed. Eleven patients (16%) had left ventricular hypertrophy with or without left atrial enlargement. CTR was best related with left atrial size (p<0.01) as well as with the end-systolic and end-diastolic left ventricular diameter (p<0.05). CTR greater than 0.57 was always related with pathologic findings by echocardiography. Conclusions: We conclude that although measurement of CTR on chest X-ray provides a quick estimation of cardiac size, it does not differentiate normal from abnormal heart. Echocardiography provides accurate measurements of individual cardiac chamber dimensions and readily detects the presence of pericardial fluid.
Choudhury L, Rosen SD, Patel D, et al., 1997, Coronary vasodilator reserve in primary and secondary left ventricular hypertrophy - A study with positron emission tomography, EUROPEAN HEART JOURNAL, Vol: 18, Pages: 108-116, ISSN: 0195-668X
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- Citations: 78
Nihoyannopoulos P, 1997, Cardiovascular manifestation in pregnancy and the approach to diagnosis of cardiac disorder, Heart disease in pregnancy, Editors: Oakley, Publisher: BMJ publishers, Pages: 52-62
Choudhury L, Rosen SD, Lefroy DC, et al., 1996, Myocardial beta adrenoceptor density in primary and secondary left ventricular hypertrophy, EUROPEAN HEART JOURNAL, Vol: 17, Pages: 1703-1709, ISSN: 0195-668X
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- Citations: 32
Ikonomidis I, Economou EV, Pitsavos C, et al., 1996, Severity of coronary artery disease is associated to macrophage colony stimulating factor, interleukin 1b and 6 plasma levels., CIRCULATION, Vol: 94, Pages: 467-467, ISSN: 0009-7322
Iconomidis I, Cole O, Economou EV, et al., 1996, Aspirin reduces macrophage colony stimulating factor plasma levels in patients with coronary artery disease. A new therapeutic role of aspirin., CIRCULATION, Vol: 94, Pages: 463-463, ISSN: 0009-7322
Albrecht T, Cosgrove DO, Correas JM, et al., 1996, Renal, hepatic, and cardiac enhancement on Doppler and gray-scale sonograms obtained with EchoGen, ACADEMIC RADIOLOGY, Vol: 3, Pages: S198-S200, ISSN: 1076-6332
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- Citations: 9
Rallidis L, Nihoyannopoulos P, Thompson GR, 1996, Aortic stenosis in homozygous familial hypercholesterolaemia, HEART, Vol: 76, Pages: 84-85, ISSN: 1355-6037
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- Citations: 31
Rosen SD, Paulesu E, Nihoyannopoulos P, et al., 1996, Silent ischemia as a central problem: Regional brain activation compared in silent and painful myocardial ischemia, ANNALS OF INTERNAL MEDICINE, Vol: 124, Pages: 939-+, ISSN: 0003-4819
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- Citations: 146
Rosen SD, Paulesu E, Nihoyannopoulos P, et al., 1996, Silent ischemia as a central problem: regional brain activation compared in silent and painful myocardial ischemia., Ann Intern Med, Vol: 124, Pages: 939-949, ISSN: 0003-4819
OBJECTIVE: To test whether the silence of painless myocardial ischemia is caused by abnormal handling by the central nervous system of afferent messages from the heart. DESIGN: Nonrandomized study. SETTING: A tertiary referral center (postgraduate medical school). PATIENTS: 2 matched groups of nondiabetic patients with coronary artery disease. Group A consisted of nine patients with reproducible stress-induced angina; group B consisted of nine patients with reproducible stress-induced myocardial ischemia but no angina. INTERVENTIONS: Intravenous placebo infusion and low-dose (5 and 10 micrograms/ kg per minute) and high-dose (20 to 35 micrograms/kg per minute) dobutamine infusions. MEASUREMENTS: Positron emission tomography was used to measure regional cerebral blood flow changes as an index of neuronal activation during painful and silent myocardial ischemia induced by intravenous dobutamine. RESULTS: Regional cerebral blood flow changes during myocardial ischemia were compared with those during baseline conditions and during placebo infusion. During myocardial ischemia, regional cerebral blood flow increased bilaterally in the thalami and prefrontal, basal frontal, and ventral cingulate corticles in patients in group A. Both thalami were activated in group B, but cortical activation was limited to the right frontal region. A formal comparison of groups A and B showed significant differences (P < 0.01) in activation of the basal frontal cortex, ventral cingulate cortex, and left temporal pole. In both groups, thalamic regional cerebral blood flow remained increased after the symptoms and signs of ischemia had ceased. CONCLUSIONS: Bilateral activation of the thalamus can be shown in both angina and silent ischemia; thus, peripheral nerve dysfunction cannot completely explain silent ischemia. Frontal cortical activation appears to be necessary for the sensation of pain. Abnormal central processing of afferent pain messages from the heart may play a determining rol
Rallidis L, Cokkinos P, Bouris C, et al., 1996, Exercise induces a greater magnitude of ischaemia than dobutamine echocardiography in patients with coronary artery disease, HEART, Vol: 75, Pages: 46-46, ISSN: 1355-6037
Nihoyannopoulos P, Marsonis A, Joshi J, et al., 1996, The magnitude of myocardial dysfunction is greater in painful than in painless myocardial ischaemia. An exercise echocardiographic study., HEART, Vol: 75, Pages: 47-47, ISSN: 1355-6037
Parthenakis F, Skalidis E, Simantirakis E, et al., 1996, Absence of atherosclerotic lesions in the thoracic aorta indicates absence of significant coronary artery disease., Am J Cardiol, Vol: 77, ISSN: 0002-9149
Atherosclerotic lesions may be readily visualized in the thoracic aorta using transesophageal echocardiography. The absence of aortic plaque in the thoracic aorta rules out significant coronary artery obstruction whereas the existence of the former appears to be a sensitive and specific predictor of the latter.
Nihoyannopoulos P, Vardas P, Parthenakis F, 1996, QT interval in cardiac amyloidosis - Reply, CLINICAL CARDIOLOGY, Vol: 19, Pages: A22-&, ISSN: 0160-9289
Gilligan DM, Nihoyannopoulos P, Fletcher A, et al., 1996, Symptoms of hypertrophic cardiomyopathy, with special emphasis on syncope and postprandial exacerbation of symptoms, CLINICAL CARDIOLOGY, Vol: 19, Pages: 371-378, ISSN: 0160-9289
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- Citations: 14
Nihoyannopoulos P, 1996, Contrast echocardiography, CLINICAL RADIOLOGY, Vol: 51, Pages: 28-30, ISSN: 0009-9260
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- Citations: 8
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