Imperial College London
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ProfessorPatriciaPrice

Faculty of Medicine, Department of Surgery & Cancer

Visiting Professor
 
 
 
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Contact

 

p.price

 
 
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Location

 

BN1/24 B BlockHammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Saleem:2000,
author = {Saleem, A and Aboagye, EO and Price, PM},
journal = {Adv Drug Deliv Rev},
pages = {21--39},
title = {In vivo monitoring of drugs using radiotracer techniques},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10699303},
volume = {41},
year = {2000}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - There is an increasing realization of the role of non-invasive monitoring of drug pharmacology. In this review, we discuss the role of positron emission tomography in such monitoring of tumour and normal tissue drug pharmacokinetics as well as assessment of tumour response, drug-receptor interactions and mechanisms of drug action and resistance. These studies represent a multidisciplinary research effort involving radiochemists, imaging scientists, clinicians, pharmacologists and mathematical modellers. This review evaluates achievements in the field from assessment of commonly used therapeutic agents such as 5-fluorouracil to target specific molecules such as markers for gene expression. It is envisaged that application of this technology will facilitate rational drug design and rapid translation of new ideas to the bedside.
AU  - Saleem,A
AU  - Aboagye,EO
AU  - Price,PM
EP  - 39
PY  - 2000///
SP  - 21
TI  - In vivo monitoring of drugs using radiotracer techniques
T2  - Adv Drug Deliv Rev
UR  - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10699303
VL  - 41
ER  -
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