Publications

BibTex format

@article{Bernatsky:2017:10.1136/lupus-2016-000187,
author = {Bernatsky, S and Velásquez, García HA and Spinelli, JJ and Gaffney, P and Smedby, KE and Ramsey-Goldman, R and Wang, SS and Adami, H-O and Albanes, D and Angelucci, E and Ansell, SM and Asmann, YW and Becker, N and Benavente, Y and Berndt, SI and Bertrand, KA and Birmann, BM and Boeing, H and Boffetta, P and Bracci, PM and Brennan, P and Brooks-Wilson, AR and Cerhan, JR and Chanock, SJ and Clavel, J and Conde, L and Cotenbader, KH and Cox, DG and Cozen, W and Crouch, S and De, Roos AJ and de, Sanjose S and Di, Lollo S and Diver, WR and Dogan, A and Foretova, L and Ghesquières, H and Giles, GG and Glimelius, B and Habermann, TM and Haioun, C and Hartge, P and Hjalgrim, H and Holford, TR and Holly, EA and Jackson, RD and Kaaks, R and Kane, E and Kelly, RS and Klein, RJ and Kraft, P and Kricker, A and Lan, Q and Lawrence, C and Liebow, M and Lightfoot, T and Link, BK and Maynadie, M and McKay, J and Melbye, M and Molina, TJ and Monnereau, A and Morton, LM and Nieters, A and North, KE and },
doi = {10.1136/lupus-2016-000187},
journal = {Lupus Science & Medicine},
title = {Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.},
url = {http://dx.doi.org/10.1136/lupus-2016-000187},
volume = {4},
year = {2017}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objective: Determinants of the increased risk of diffuse large B-cell lymphoma (DLBCL) in SLE are unclear. Using data from a recent lymphoma genome-wide association study (GWAS), we assessed whether certain lupus-related single nucleotide polymorphisms (SNPs) were also associated with DLBCL. Methods: GWAS data on European Caucasians from the International Lymphoma Epidemiology Consortium (InterLymph) provided a total of 3857 DLBCL cases and 7666 general-population controls. Data were pooled in a random-effects meta-analysis. Results: Among the 28 SLE-related SNPs investigated, the two most convincingly associated with risk of DLBCL included the CD40 SLE risk allele rs4810485 on chromosome 20q13 (OR per risk allele=1.09, 95% CI 1.02 to 1.16, p=0.0134), and the HLA SLE risk allele rs1270942 on chromosome 6p21.33 (OR per risk allele=1.17, 95% CI 1.01 to 1.36, p=0.0362). Of additional possible interest were rs2205960 and rs12537284. The rs2205960 SNP, related to a cytokine of the tumour necrosis factor superfamily TNFSF4, was associated with an OR per risk allele of 1.07, 95% CI 1.00 to 1.16, p=0.0549. The OR for the rs12537284 (chromosome 7q32, IRF5 gene) risk allele was 1.08, 95% CI 0.99 to 1.18, p=0.0765. Conclusions: These data suggest several plausible genetic links between DLBCL and SLE.
AU  - Bernatsky,S
AU  - Velásquez,García HA
AU  - Spinelli,JJ
AU  - Gaffney,P
AU  - Smedby,KE
AU  - Ramsey-Goldman,R
AU  - Wang,SS
AU  - Adami,H-O
AU  - Albanes,D
AU  - Angelucci,E
AU  - Ansell,SM
AU  - Asmann,YW
AU  - Becker,N
AU  - Benavente,Y
AU  - Berndt,SI
AU  - Bertrand,KA
AU  - Birmann,BM
AU  - Boeing,H
AU  - Boffetta,P
AU  - Bracci,PM
AU  - Brennan,P
AU  - Brooks-Wilson,AR
AU  - Cerhan,JR
AU  - Chanock,SJ
AU  - Clavel,J
AU  - Conde,L
AU  - Cotenbader,KH
AU  - Cox,DG
AU  - Cozen,W
AU  - Crouch,S
AU  - De,Roos AJ
AU  - de,Sanjose S
AU  - Di,Lollo S
AU  - Diver,WR
AU  - Dogan,A
AU  - Foretova,L
AU  - Ghesquières,H
AU  - Giles,GG
AU  - Glimelius,B
AU  - Habermann,TM
AU  - Haioun,C
AU  - Hartge,P
AU  - Hjalgrim,H
AU  - Holford,TR
AU  - Holly,EA
AU  - Jackson,RD
AU  - Kaaks,R
AU  - Kane,E
AU  - Kelly,RS
AU  - Klein,RJ
AU  - Kraft,P
AU  - Kricker,A
AU  - Lan,Q
AU  - Lawrence,C
AU  - Liebow,M
AU  - Lightfoot,T
AU  - Link,BK
AU  - Maynadie,M
AU  - McKay,J
AU  - Melbye,M
AU  - Molina,TJ
AU  - Monnereau,A
AU  - Morton,LM
AU  - Nieters,A
AU  - North,KE
AU  - Novak,AJ
AU  - Offit,K
AU  - Purdue,MP
AU  - Rais,M
AU  - Riby,J
AU  - Roman,E
AU  - Rothman,N
AU  - Salles,G
AU  - Severi,G
AU  - Severson,RK
AU  - Skibola,CF
AU  - Slager,SL
AU  - Smith,A
AU  - Smith,MT
AU  - Southey,MC
AU  - Staines,A
AU  - Teras,LR
AU  - Thompson,CA
AU  - Tilly,H
AU  - Tinker,LF
AU  - Tjonneland,A
AU  - Turner,J
AU  - Vajdic,CM
AU  - Vermeulen,RCH
AU  - Vijai,J
AU  - Vineis,P
AU  - Virtamo,J
AU  - Wang,Z
AU  - Weinstein,S
AU  - Witzig,TE
AU  - Zelenetz,A
AU  - Zeleniuch-Jacquotte,A
AU  - Zhang,Y
AU  - Zheng,T
AU  - Zucca,M
AU  - Clarke,AE
DO  - 10.1136/lupus-2016-000187
PY  - 2017///
SN  - 2053-8790
TI  - Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.
T2  - Lupus Science & Medicine
UR  - http://dx.doi.org/10.1136/lupus-2016-000187
UR  - http://hdl.handle.net/10044/1/54937
VL  - 4
ER  -

Download

ProfessorPaoloVineis

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)