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@article{Anand:2003:10.1016/j.bbrc.2003.09.087,
author = {Anand, PK and Kaul, D},
doi = {10.1016/j.bbrc.2003.09.087},
journal = {Biochem Biophys Res Commun},
pages = {876--877},
title = {Vitamin D3-dependent pathway regulates TACO gene transcription.},
url = {http://dx.doi.org/10.1016/j.bbrc.2003.09.087},
volume = {310},
year = {2003}
}

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TY  - JOUR
AB  - Recently, gene coding for tryptophan-aspartate containing coat protein (TACO) has been recognized to play a crucial role in the survival of Mycobacterium tuberculosis within human macrophages. Since regulation of TACO gene is still poorly understood, the present study was addressed to explore the role of vitamins (A, C, D, and E) in TACO gene transcription. Such a study revealed that synergistic action of vitamin D(3) and retinoic acid (RA) had inherent ability to down-regulate TACO gene transcription in human macrophages. Based upon these results, we propose that synergistic action of RA+vitamin D may be of importance in the prevention/control of M. tuberculosis infection.
AU  - Anand,PK
AU  - Kaul,D
DO  - 10.1016/j.bbrc.2003.09.087
EP  - 877
PY  - 2003///
SN  - 0006-291X
SP  - 876
TI  - Vitamin D3-dependent pathway regulates TACO gene transcription.
T2  - Biochem Biophys Res Commun
UR  - http://dx.doi.org/10.1016/j.bbrc.2003.09.087
UR  - https://www.ncbi.nlm.nih.gov/pubmed/14550285
VL  - 310
ER  -

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Dr Paras Anand

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