Imperial College London

Dr Peter Hellyer

Faculty of MedicineDepartment of Brain Sciences

Honorary Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 9568peter.hellyer

 
 
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Location

 

4.35Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Hughes:2020:10.1016/j.mri.2020.02.007,
author = {Hughes, SW and Hellyer, PJ and Sharp, DJ and Newbould, RD and Patel, MC and Strutton, PH},
doi = {10.1016/j.mri.2020.02.007},
journal = {Magnetic Resonance Imaging},
pages = {65--70},
title = {Diffusion tensor imaging of lumbar spinal nerves reveals changes in microstructural integrity following decompression surgery associated with improvements in clinical symptoms: A case report},
url = {http://dx.doi.org/10.1016/j.mri.2020.02.007},
volume = {69},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The outcomes from spinal nerve decompression surgery are highly variable with a sizable proportion of elderly foraminal stenosis patients not regaining good pain relief. A better understanding of nerve root compression before and following decompression surgery and whether these changes are mirrored by improvements in symptoms may help to improve clinical decision-making processes. This case study used a combination of diffusion tensor imaging (DTI), clinical questionnaires and motor neurophysiology assessments before and up to 3 months following spinal decompression surgery. In this case report, a 70-year-old women with compression of the left L5 spinal nerve root in the L5-S1 exit foramina was recruited to the study. At 3 months following surgery, DTI revealed marked improvements in left L5 microstructural integrity to a similar level to that seen in the intact right L5 nerve root. This was accompanied by a gradual improvement in pain-related symptoms, mood and disability score by 3 months. Using this novel multimodal approach, it may be possible to track concurrent improvements in pain-related symptoms, function and microstructural integrity of compressed nerves in elderly foraminal stenosis patients undergoing decompression surgery.
AU - Hughes,SW
AU - Hellyer,PJ
AU - Sharp,DJ
AU - Newbould,RD
AU - Patel,MC
AU - Strutton,PH
DO - 10.1016/j.mri.2020.02.007
EP - 70
PY - 2020///
SN - 0730-725X
SP - 65
TI - Diffusion tensor imaging of lumbar spinal nerves reveals changes in microstructural integrity following decompression surgery associated with improvements in clinical symptoms: A case report
T2 - Magnetic Resonance Imaging
UR - http://dx.doi.org/10.1016/j.mri.2020.02.007
UR - https://www.ncbi.nlm.nih.gov/pubmed/32084517
UR - http://hdl.handle.net/10044/1/77952
VL - 69
ER -