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@article{Haywood:2015:10.1002/chem.201501089,
author = {Haywood, T and Kealey, S and Sanchez-Cabezas, S and Hall, J and Allott, L and Smith, G and plisson, C and Miller, PW},
doi = {10.1002/chem.201501089},
journal = {Chemistry-A European Journal},
pages = {9034--9038},
title = {Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget},
url = {http://dx.doi.org/10.1002/chem.201501089},
volume = {21},
year = {2015}
}

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TY  - JOUR
AB  - Herein a new 11C radiolabelling strategy for the fast and efficient synthesis of thioureas and related derivatives using the novel synthon, 11CS2, is reported. This approach has enabled the facile labelling of a potent progesterone receptor (PR) agonist, [11C]Tanaproget, by the intramolecular reaction of the acyclic aminohydroxyl precursor with 11CS2, which has potential applications as a positron emission tomography radioligand for cancer imaging.
AU  - Haywood,T
AU  - Kealey,S
AU  - Sanchez-Cabezas,S
AU  - Hall,J
AU  - Allott,L
AU  - Smith,G
AU  - plisson,C
AU  - Miller,PW
DO  - 10.1002/chem.201501089
EP  - 9038
PY  - 2015///
SN  - 1521-3765
SP  - 9034
TI  - Carbon-11 Radiolabelling of Organosulfur Compounds: 11C Synthesis of the Progesterone Receptor Agonist Tanaproget
T2  - Chemistry-A European Journal
UR  - http://dx.doi.org/10.1002/chem.201501089
VL  - 21
ER  -

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