Project Manager and Co-Investigator, the INTERMAP Study
Project Manager, the AIRLESS Study
Scientific Strategy, Imperial College Wellcome Trust Centre for Global Health Research
Investigator, MRC-PHE Centre for Environment & Health
Research Interests and Responsibilities
Cardiovascular disease epidemiology and prevention; relationship of diet and blood pressure; environmental health risk factors; application of metabonomics methods to large-scale population studies; project management; database management; applied statistics; biobank.
My research focuses on nutritional and cardiovascular epidemiology and translational medicine. I have collaborated with inter-disciplinary research scientists in developing and testing new biostatistical methods for epidemiological data analysis and application of metabolic phenotyping to large-scale epidemiological studies. I have worked on a number of research projects investigating environmental health risk factors in relations to respiratory and cardiovascular diseases.
Chan Q, Stamler J, Brown IJ, Daviglus ML, Van Horn L, Dyer AR, Oude Griep LM, Miura K, Ueshima H, Zhao L, Nicholson JK, Holmes E, Elliott P. Relation of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study. J Hum Hypertens. 2014; 28(6):353-9. PubMed PMID: 24257514; PubMed Central PMCID: PMC4013197.
Elliott P, Posma JM, Chan Q, Garcia-Perez I, Wijeyesekera A, Bictash M, D Ebbels TM, Ueshima H, Zhao L, van Horn L, Daviglus M, Stamler J, Holmes E, Nicholson JK. Urinary metabolic signatures of human adiposity. Sci Transl Med. 2015 Apr 29;7(285):285ra62. PubMed PMID: 25925681
Chan Q, Stamler J, Oude Griep LM, Daviglus ML, Van Horn L, Elliott P. An update on nutrients and blood pressure: Summary of INTERMAP Study findings. J Atheroscler Thromb. 2016; 23:276-289. PMID: 26686565
Chan Q, Loo R, Ebbels TMD, Van Horn L, Daviglus ML, Stamler J, Nicholson JK, Holmes E, Elliott P. Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: An overview. Hypertension Research 2016 Dec 22. DOI:10.1038/hr.2016.164 PMID: 28003647
Chekmeneva E, Dos Santos Correia G, Chan Q, Wijeyesekera A, Tin A, Young JH, Elliott P, Nicholson JK, Holmes E. Optimization and application of direct infusion nanoelectrospray HRMS method for large-scale urinary metabolic phenotyping in molecular epidemiology. J Proteome Res. 2017 Mar 14. DOI: 10.1021/acs.jproteome.6b01003 PMID: 28245357
et al., 2018, Relation of Dietary Sodium (Salt) to Blood Pressure and Its Possible Modulation by Other Dietary Factors: The INTERMAP Study, Hypertension, Vol:71, ISSN:0194-911X, Pages:631-637
et al., 2018, Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for CVD and diabetes: Airwave Health Monitoring Study, British Journal of Nutrition, Vol:119, ISSN:0007-1145, Pages:695-705
et al., 2018, Blood pressure-lowering drugs and secondary prevention of cardiovascular disease: systematic review and meta-analysis., J Hypertens
et al., 2018, Reliability of plasma polar metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry, Plos One, Vol:13, ISSN:1932-6203
et al., 2017, Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview, Hypertension Research, Vol:40, ISSN:0916-9636, Pages:336-345