Imperial College London

Dr Robert Boyle

Faculty of MedicineNational Heart & Lung Institute

Reader in Paediatric Allergy
 
 
 
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Contact

 

+44 (0)20 3312 7892r.boyle Website

 
 
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Location

 

Paediatric Research UnitQueen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Cepeda:2017:10.1007/s00408-017-0044-z,
author = {Cepeda, AM and Thawer, S and Boyle, RJ and Villalba, S and Jaller, R and Tapias, E and Segura, AM and Villegas, R and Garcia, Larsen V},
doi = {10.1007/s00408-017-0044-z},
journal = {Lung},
pages = {683--692},
title = {Diet and respiratory health in children from 11 Latin American countries: evidence from ISAAC Phase III},
url = {http://dx.doi.org/10.1007/s00408-017-0044-z},
volume = {195},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Background and Aim The burden of childhood asthma andits risk factors is an important but neglected public healthchallenge in Latin America. We investigated the associationbetween allergic symptoms and dietary intake inchildren from this region.Methods As part of the International Study of Asthma andAllergies in Childhood (ISAAC) Phase III, questionnairecollected dietary intake was investigated in relation to riskof parental/child reported current wheeze (primary outcome)and rhino-conjunctivitis and eczema. Per-countryadjusted logistic regressions were performed, and combinedeffect sizes were calculated with meta-analyses.Results 143,967 children from 11 countries had completedata. In children aged 6–7 years, current wheeze wasnegatively associated with higher fruit intake (adjustedodds ratio [aOR] 0.65; 95% CI 0.74, 0.97). Current rhinoconjunctivitisand eczema were statistically negativelyassociated with fruit intake (aOR 0.72; 95% CI 0.64, 0.82;and OR 0.64, 95% CI 0.56, 0.74, respectively).Vegetable intake was negatively associated with risk ofsymptoms in younger children, but these associations wereattenuated in the 13–14 years old group. Fastfood/burgerintake was positively associated with all three outcomes inthe older children.Conclusion A higher intake of fruits and vegetables wasassociated with a lower prevalence of allergic symptoms inLatin American children. Conversely, intake of fastfood was positively associated with a higher prevalence ofwheeze in adolescents. Improved dietary habits in childrenmight help reduce the epidemic of allergic symptoms inLatin America. Food interventions in asthmatic childrenare needed to evaluate the possible public health impact ofa better diet on respiratory health.
AU - Cepeda,AM
AU - Thawer,S
AU - Boyle,RJ
AU - Villalba,S
AU - Jaller,R
AU - Tapias,E
AU - Segura,AM
AU - Villegas,R
AU - Garcia,Larsen V
DO - 10.1007/s00408-017-0044-z
EP - 692
PY - 2017///
SN - 0341-2040
SP - 683
TI - Diet and respiratory health in children from 11 Latin American countries: evidence from ISAAC Phase III
T2 - Lung
UR - http://dx.doi.org/10.1007/s00408-017-0044-z
UR - http://hdl.handle.net/10044/1/50380
VL - 195
ER -