Imperial College London
Alternate

Dr Robert Boyle

Faculty of Medicine, National Heart & Lung Institute

Reader in Paediatric Allergy
 
 
 
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Contact

 

+44 (0)20 3312 7892r.boyle Website

 
 
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Location

 

Paediatric Research UnitQueen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Turner:2018:10.1016/j.jaip.2017.12.015,
author = {Turner, PJ and Campbell, DE and Boyle, R and Levin, ME},
doi = {10.1016/j.jaip.2017.12.015},
journal = {Journal of Allergy and Clinical Immunology: In Practice},
pages = {367--375},
title = {Primary prevention of food allergy: translating evidence from clinical trials to population-based recommendations},
url = {http://dx.doi.org/10.1016/j.jaip.2017.12.015},
volume = {6},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Given the prevalence and impact of childhood food allergy, there is increasing interest in interventions targeting disease prevention. Although interventions such as early introduction of dietary peanut have demonstrated efficacy in a small number of well-conducted randomized clinical trials, evidence for broader effectiveness and successful implementation at a population level is still lacking, although epidemiological data suggest that such strategies are likely to be successful, at least for peanut. In this commentary, we explore the issues of translating evidence of efficacy studies (performed under optimal conditions) to make policy recommendations at a population level, and highlight potential benefits, harms, and unintended consequences of making population-based recommendations on the basis of randomized controlled trials. We discuss the complexity and barriers to effective primary and secondary prevention intervention implementation in resource-poor settings.
AU  - Turner,PJ
AU  - Campbell,DE
AU  - Boyle,R
AU  - Levin,ME
DO  - 10.1016/j.jaip.2017.12.015
EP  - 375
PY  - 2018///
SN  - 2213-2198
SP  - 367
TI  - Primary prevention of food allergy: translating evidence from clinical trials to population-based recommendations
T2  - Journal of Allergy and Clinical Immunology: In Practice
UR  - http://dx.doi.org/10.1016/j.jaip.2017.12.015
UR  - http://hdl.handle.net/10044/1/55310
VL  - 6
ER  -
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