Imperial College London

Dr Robin Carhart-Harris

Faculty of MedicineDepartment of Medicine

Research Fellow



+44 (0)20 7594 7992r.carhart-harris




Mrs Margaret Collett +44 (0)20 7594 7992




Burlington DanesHammersmith Campus






Head of Psychedelic Research, Centre for Neuropsychopharmacology, Division of Brain Sciences, Faculty of Medicine, Imperial College London



TEDx talk

How to change the world

The importance of a scientific approach to psychedelics



Imperial College London



40. Carhart-Harris, R. L. et alLancet Psychiatry

39. Nour et al. [senior author] British Journal of Psychiatry. Submitted.

38. Nour et al. [senior author] Frontiers in Human Neuroscience. Accepted.

37: Lebedev AV, Kaelen M, Lövdén M, Nilsson J, Feilding A, Nutt DJ, Carhart-Harris RL (2016) LSD-induced entropic brain activity predicts subsequent personality change. Hum Brain Mapp. doi: 10.1002/hbm.23234.

36: Roseman L, Sereno MI, Leech R, Kaelen M, Orban C, McGonigle J, Feilding A, Nutt DJ, Carhart-Harris RL (2016) LSD alters eyes-closed functional connectivity within the early visual cortex in a retinotopic fashion. Hum Brain Mapp. doi: 10.1002/hbm.23224.

35: Tagliazucchi E, Roseman L, Kaelen M, Orban C, Muthukumaraswamy SD, Murphy K,Laufs H, Leech R, McGonigle J, Crossley N, Bullmore E, Williams T, Bolstridge M, Feilding A, Nutt DJ, Carhart-Harris R (2016) Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution. Curr Biol. 25;26(8):1043-50. doi: 10.1016/j.cub.2016.02.010.

34: Kaelen M, Roseman L, Kahan J, Santos-Ribeiro A, Orban C, Lorenz R, Barrett FS, Bolstridge M, Williams T, Williams L, Wall MB, Feilding A, Muthukumaraswamy S, Nutt DJ, Carhart-Harris R (2016) LSD modulates music-induced imagery via changes in parahippocampal connectivity. Eur Neuropsychopharmacol. pii: S0924-977X(16)30016-5. doi: 10.1016/j.euroneuro.2016.03.018.

33: Carhart-Harris RL, Muthukumaraswamy S, Roseman L, Kaelen M, Droog W, Murphy K, Tagliazucchi E, Schenberg EE, Nest T, Orban C, Leech R, Williams LT, Williams TM, Bolstridge M, Sessa B, McGonigle J, Sereno MI, Nichols D, Hellyer PJ, Hobden P, Evans J, Singh KD, Wise RG, Curran HV, Feilding A, Nutt DJ (2016) Neural correlates of  the LSD experience revealed by multimodal neuroimaging. Proc Natl Acad Sci U S A. 113(17):4853-8. doi: 10.1073/pnas.1518377113.

32: Terhune DB, Luke DP, Kaelen M, Bolstridge M, Feilding A, Nutt D, Carhart-Harris R, Ward J. A placebo-controlled investigation of synaesthesia-like experiences under LSD. Neuropsychologia. 2016 Apr 5. pii: S0028-3932(16)30113-0.  doi: 10.1016/j.neuropsychologia.2016.04.005.

31: Speth J, Speth C, Kaelen M, Schloerscheidt AM, Feilding A, Nutt DJ, Carhart-Harris RL. Decreased mental time travel to the past correlates with default-mode network disintegration under lysergic acid diethylamide. J Psychopharmacol. 2016 Apr;30(4):344-53. doi: 10.1177/0269881116628430.

30. Carhart-Harris RL, Kaelen M, Bolstridge M, Williams TM, Williams LT, Underwood R, Feilding A, Nutt DJ (2016) The paradoxical psychological effects of lysergic acid diethylamide (LSD). Psychol Med 5:1-12.

29. Kaelen M, Barrett F, Roseman L, Lorenz R, Family N, Bolstridge M, Curran V, Feilding A, Nutt DJ, Carhart-Harris RL (2015) LSD enhances the emotional response to music. Psychopharmacology 232(19):3607-14.


28. Lebedev AV, Lövdén M, Rosenthal G, Feilding A, Nutt DJ, Carhart-Harris RL (2015)

Finding the self by losing the self: Neural correlates of ego-dissolution under psilocybin. Hum Brain Mapp. doi: 10.1002/hbm.22833


27. Steeds H, Carhart-Harris RL, Stone JM (2015) Drug models of schizophrenia. Ther Adv  Psychopharmacol. 2015 Feb;5(1):43-58. doi: 10.1177/2045125314557797


26. Turton S, Nutt DJ, Carhart-Harris RL (2015) A Qualitative Report on the Subjective Experience of Intravenous Psilocybin Administered in an fMRI Environment. Curr Drug Abuse Rev. Epub ahead of print.


25. Carhart-Harris RL, Kaelen M, Whalley M, Bolstridge M, Feilding A, Nutt DJ (2014) LSD enhances suggestibility in healthy volunteers. Psychopharmacology. doi: 10.1007/s00213-014-3714-z.


24. Carhart-Harris RL, Kaelen M, Nutt DJ (2014) How do hallucinogens work on the brain? The Psychologist. 27 (9). 


23. Carhart-Harris & Nutt (2014) Was it a vision or a waking dream? Frontiers in Psychology. doi: 10.3389/fpsyg.2014.00255.


22. Roseman L, Leech R, Feilding A, Nutt DJ, Carhart-Harris RL (2014) The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers. Frontiers in Human Neuroscience. doi: 10.3389/fnhum.2014.00204.


21. Carhart-Harris RL*, Muthukumuraswarmy S*, Moran RJ, Brookes MJ, Williams TM, Errtizoe D, Sessa B, Papadopoulos A, Bolstridge M, Singh KD, Feilding A, Friston KJ, Nutt DJ et al. (2013) Broadband cortical desynchronization underlies the human psychedelic state. J Neuroscience 33(38):15171-83. doi: 10.1523/JNEUROSCI.2063-13.2013. * Shared first authors.


20. Carhart-Harris RL, Murphy K, Leech R, Erritzoe D, Wall MB, Ferguson B, Williams LT, Roseman L, Brugger S, De Meer I, Tanner M, Tyacke R, Wolff K, Sethi A, Bloomfield MA, Williams TM, Bolstridge M, Stewart L, Morgan C, Newbould RD, Feilding A, Curran HV, Nutt DJ (2014) The effects of acutely administered MDMA on spontaneous brain function measured with arterial spin labelling and BOLD resting-state functional connectivity. Biol Psych. doi: 10.1016/j.biopsych.2013.12.015.


19. Carhart-Harris RL, Wall MB, Erritzoe D, Kaelen M, Ferguson B, De Meer I, Tanner M, Bloomfield M, Williams TM, Bolstridge M, Stewart L, Morgan CJ, Newbould RD, Feilding A, Curran HV, Nutt DJ (2013) The effect of MDMA on recollecting autobiographical memories: an fMRI study with implications for MDMA-assisted psychotherapy. Int J Neuropsychopharmacology 17:1-14. doi: 10.1017/S1461145713001405.


18. Carhart-Harris RL, Leech R, Hellyer PJ, Shanahan M, Feilding A, Tagliazucchi E, Chialvo DR, Nutt DJ. (2014) The entropic brain: A theory of conscious states informed by neuroimaging research with psychedelic drugs. Frontiers in Human Neuroscience. doi: 10.3389/fnhum.2014.00020.


17. Tagliazucchi E, Carhart-Harris RL, Nutt DJ, Chialvo D (2014) Enhanced repertoire of brain dynamical states during the psychedelic experience. Human Brain Mapping. doi: 10.1002/hbm.22562


16. Leech R, Scott G, Carhart-Harris RL, Turkheimer F, Taylor-Robinson S, Sharp D (2013) A spatial relationship between task positive and task negative networks. PloS One.


15. Petri G, Expert P, Turkheimer F, Hellyer P, Carhart-Harris RL (2014) Homological backbone of brain functional networks. J R Soc Interface. 11(101).


14. Carhart-Harris RL, Nutt DJ, Stone JM (2013) Psychiatry’s next top-model: Cause for a re-think on drug models of psychosis and other psychiatric disorders. Journal of Psychopharmacology 27(9):771-8.


13. Carhart-Harris RL & Nutt DJ (2013) Experienced drug users assess the relative harms and benefits of drugs: a web-based survey. Journal of Psychoactive drugs 45(4):322-8.


12. Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, Tyacke RJ, Leech R, Malizia AL, Murphy K, Hobden P, Evans J, Feilding A, Wise RG, Nutt DJ (2012) Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin. Proc Natl Acad Sci U S A 109:2138-43.


11. Carhart-Harris RL, R. Leech, D. Erritzoe, T. M. Williams, J. M. Stone, J. Evans, D. J. Sharp, A. Feilding, R. G. Wise, and D. J. Nutt (2012) Functional Connectivity Measures after Psilocybin Inform a Novel Hypothesis of Early Psychosis.  Schizophr Bull 39(6):1343-51.


10. Carhart-Harris RL, Leech R, Williams TM, Erritzoe D, Abbasi N, Bargiotas T, Hobden P, Sharp DJ, Evans J, Feilding A, Wise RG, Nutt DJ (2012) Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin. Br J Psychiatry. 200(3):238-44.


9. Carhart-Harris RL & Friston KJ (2012) Free-energy and Freud: an update. Ch 13. From the couch to the lab: Trends in psychodynamic neuroscience. Ed. Fotopoulou A et al. Oxford Books.


8. Carhart-Harris RL, King LA, Nutt DJ (2011) A web-based survey on mephedrone. Drug Alcohol Depend 118(1):19-22.


7. Carhart-Harris RL, Friston KJ (2010) The default-mode, ego-functions and free energy: a neurobiological account of Freudian ideas. Brain 133(4):1265-83.


6. Carhart-Harris RL, Williams TM, Sessa B, Tyacke R, Feilding A, Nutt DJ (2010) The administration of psilocybin to healthy hallucinogen-experienced volunteers in a mock-fMRI environment: a preliminary investigation of tolerability. Journal of Psychopharmacology. 25(11):1562-7.


5. Carhart-Harris RL & Nutt DJ (2010) User perceptions of the benefits and harms of hallucinogenic drug use: a web-based questionnaire study. Journal of Substance Use 15(4) 283-300.


4. Carhart-Harris RL, Nutt DJ, Munafo MR, Christmas DM, Wilson SJ (2009) Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls. Psychopharmacology (Berl) 206(2):187-96


3. Carhart-Harris RL, Nutt DJ, Munafo M, Wilson SJ (2009) Current and former ecstasy users report different sleep to matched controls: a web-based questionnaire study. J Psychopharmacol 23(3):249-57


2. Carhart-Harris RL, Mayberg HS, Malizia ML, Nutt D J (2008) Mourning & Melancholia revisited: Correspondences between principles of Freudian metapsychology and empirical findings in neuropsychiatry. Annals of General Psychiatry 7 (1): 9.


1. Carhart-Harris R (2007) Waves of the unconscious. The neurophysiology of dreamlike phenomena 



Carhart-Harris R, Lawton G, 2017, Trip advisor, New Scientist, Vol:235, ISSN:0262-4079, Pages:42-43

Carhart-Harris RL, Erritzoe D, Haijen E, et al., 2017, Psychedelics and connectedness., Psychopharmacology (berl)

Carhart-Harris RL, Goodwin GM, 2017, The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future, Neuropsychopharmacology, Vol:42, ISSN:0893-133X, Pages:2105-2113

Carhart-Harris RL, Nutt DJ, 2017, Serotonin and brain function: a tale of two receptors., J Psychopharmacol, Vol:31, Pages:1091-1120

Carhart-Harris RL, Roseman L, Bolstridge M, et al., 2017, Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms, Scientific Reports, Vol:7, ISSN:2045-2322

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