Imperial College London
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Dr Rodrigo M. Carrillo Larco

Faculty of Medicine, School of Public Health

 
 
 
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Contact

 

r.carrillo-larco CV

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Carrillo:2019:10.1111/dme.14114,
author = {Carrillo, Larco R and Aparcana-Granda, DJ and R, Mejia J and Barengo, NC and Bernabe-Ortiz, A},
doi = {10.1111/dme.14114},
journal = {Diabetic Medicine},
pages = {1573--1584},
title = {Risk scores for type 2 diabetes mellitus in Latin America: A systematic review of population-based studies},
url = {http://dx.doi.org/10.1111/dme.14114},
volume = {36},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Aims: Weaimed tosummarize the evidence ondiabetes risk scores forLatin American  populations.Methods:A  systematic  review  was  conducted  (CRD42019122306)looking  for  diagnostic  and prognostic  models  for type  2  diabetes  mellitusamong  randomlyselected  adults  in Latin  Americacountries. Five databases(LILACS, Scopus, Medline, Embase and Global Health) weresearched. Type 2 diabetes mellituswasdefined using at least one blood bio-markerandthe reports needed to include information on the development and/or validation of a multivariableregressionmodel. Risk of bias was assessed withthe PROBAST guidelines.Results:Out of the1,500 reports identified, 11 were studied in detailandfivewere  included  in the qualitative  analysis.  Two  reports  were  from  Mexico,  two  from Peru,  and  one  from  Brazil.  The  number  of diabetes  casesvaried  from  48  to  207  in  the  derivations models,  whereas  these  numbers ranged  between 29 and582  in  the  validation  models. The  most common predictors were age, waist circumference and family history of diabetes, and only one study used oral glucose tolerance test as the outcome. The discrimination performance across studies was around 70% (range: 66% -72%) as per the area under the receiving-operator curve, thehighestmetric was always the negative prediction value. Sensitivity was always higher than specificity. Conclusion:There is no evidence to support the use of one risk scorethroughout Latin America. The development, validation  and  implementation  of  risk  scores  should  be  a  research  and  public  health  priorityin  Latin America to improve type 2 diabetes mellitusscreening and prevention.
AU  - Carrillo,Larco R
AU  - Aparcana-Granda,DJ
AU  - R,Mejia J
AU  - Barengo,NC
AU  - Bernabe-Ortiz,A
DO  - 10.1111/dme.14114
EP  - 1584
PY  - 2019///
SN  - 0742-3071
SP  - 1573
TI  - Risk scores for type 2 diabetes mellitus in Latin America: A systematic review of population-based studies
T2  - Diabetic Medicine
UR  - http://dx.doi.org/10.1111/dme.14114
UR  - http://hdl.handle.net/10044/1/72316
VL  - 36
ER  -
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