Imperial College London
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Dr Rodrigo M. Carrillo Larco

Faculty of Medicine, School of Public Health

 
 
 
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r.carrillo-larco CV

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Carrillo:2020:10.1111/dme.14298,
author = {Carrillo, Larco R},
doi = {10.1111/dme.14298},
journal = {Diabetic Medicine},
pages = {1519--1527},
title = {Intermediate hyperglycaemia and 10-year mortality in resource-constrained settings: The PERU Migrant Study},
url = {http://dx.doi.org/10.1111/dme.14298},
volume = {37},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AimTo determine whether intermediate hyperglycaemia, defined by fasting plasma glucose and HbA1c criteria, is associated with mortality in a 10year cohort of people in a Latin American country.MethodsAnalysis of the PERU MIGRANT Study was conducted in three different population groups (rural, ruraltourban migrant, and urban). The baseline assessment was conducted in 2007/2008, with followup assessment in 2018. The outcome was allcause mortality, and the exposure was intermediate hyperglycaemia, using three definitions: (1) impaired fasting glucose, defined according to American Diabetes Association criteria [fasting plasma glucose 5.6–6.9 mmol/l (100–125 mg/dl)]; (2) prediabetes defined according to American Diabetes Association criteria [HbA1c levels 39–46 mmol/mol (5.7–6.4%)]; and (3) prediabetes defined according to the International Expert Committee criteria [HbA1c levels 42–46 mmol/mol (6.0–6.4%)]. Crude and adjusted hazard ratios and 95% CIs were estimated using Cox proportional hazard models.ResultsAt baseline, the mean (sd) age of the study population was 47.8 (11.9) years and 52.5% of the cohort were women. The study cohort was divided into population groups as follows: 207 people (20.0%) in the rural population group, 583 (59.7%) in the ruraltourban migrant group and 198 (20.3%) in the urban population group. The prevalence of intermediate hyperglycaemia was: 6%, 12.9% and 38.5% according to the American Diabetes Association impaired fasting glucose definition, the International Expert Committee HbA1cbased definition and the American Diabetes Association HbA1cbased definition, respectively, and the mortality rate after 10 years was 63/976 (7%). Intermediate hyperglycaemia was associated with allcause mortality using the HbA1cbased definitions in the crude models [hazard ratios 2.82 (95% CI 1.59–4.99) according to the American Diabetes Association and 2.92 (95% CI 1.62–5.28) according to the Interna
AU  - Carrillo,Larco R
DO  - 10.1111/dme.14298
EP  - 1527
PY  - 2020///
SN  - 0742-3071
SP  - 1519
TI  - Intermediate hyperglycaemia and 10-year mortality in resource-constrained settings: The PERU Migrant Study
T2  - Diabetic Medicine
UR  - http://dx.doi.org/10.1111/dme.14298
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.14298
UR  - http://hdl.handle.net/10044/1/77686
VL  - 37
ER  -
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