Publications
30 results found
Dong R, Liu R, Gaffney PRJ, et al., 2019, Author Correction: Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving, Nature Chemistry, Vol: 11, Pages: 184-184, ISSN: 1755-4330
Correction to: Nature Chemistry https://doi.org/10.1038/s41557-018-0169-6, published online 3 December 2018.
Dong R, Liu R, Gaffney P, et al., 2018, Sequence-defined multifunctional polyethers via liquid-phase synthesis with molecular sieving, Nature Chemistry, Vol: 11, Pages: 136-145, ISSN: 1755-4330
Synthetic chemists have devoted tremendous effort towards the production of precision synthetic polymers with defined sequences and specific functions. However, the creation of a general technology that enables precise control over monomer sequence, with efficient isolation of the target polymers, is highly challenging. Here, we report a robust strategy for the production of sequence-defined synthetic polymers through a combination of liquid-phase synthesis and selective molecular sieving. The polymer is assembled in solution with real-time monitoring to ensure couplings proceed to completion, on a three-armed star-shaped macromolecule to maximize efficiency during the molecular sieving process. This approach is applied to the construction of sequence-defined polyethers, with side-arms at precisely defined locations that can undergo site-selective modification after polymerization. Using this versatile strategy, we have introduced structural and functional diversity into sequence-defined polyethers, unlocking their potential for real-life applications in nanotechnology, healthcare and information storage.
Dong R, Chen R, Livingston A, 2018, Iterative synthesis of sequence-defined, multifunctional, biocompatible PEGs for biomedical applications, 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, Publisher: AMER CHEMICAL SOC, ISSN: 0065-7727
Yasen W, Dong R, Zhou L, et al., 2017, Supramolecular block copolymers for gene delivery: enhancement of transfection efficiency by charge regulation, CHEMICAL COMMUNICATIONS, Vol: 53, Pages: 12782-12785, ISSN: 1359-7345
Dong R, Chen R, Livingston A, 2017, Liquid-phase iterative synthesis with OSN: A flexible and scalable platform for precision synthetic macromolecules, 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Publisher: AMER CHEMICAL SOC, ISSN: 0065-7727
Yasen W, Dong R, Zhou L, et al., 2017, Synthesis of a Cationic Supramolecular Block Copolymer with Covalent and Noncovalent Polymer Blocks for Gene Delivery, ACS Applied Materials & Interfaces, Vol: 9, Pages: 9006-9014, ISSN: 1944-8244
Dong R, Ravinathan SP, Xue L, et al., 2016, Dual-responsive aggregation-induced emission-active supramolecular nanoparticles for gene delivery and bioimaging, Chemical Communications, Vol: 52, Pages: 7950-7953, ISSN: 1359-7345
Dual-responsive aggregation-induced emission-active supramolecular fluorescent nanoparticles are reported, which have the ability to undergo a unique morphological transition combining with a cooperative optical variation in response to pH and light stimuli. The dynamic supramolecular nanoparticles show excellent biocompatibility and effective plasmid DNA condensation capability, further achieving efficient in vitro gene delivery and bioimaging.
Deng H, Su Y, Hu M, et al., 2015, Multicolor Fluorescent Polymers Inspired from Green Fluorescent Protein, Macromolecules, Vol: 48, Pages: 5969-5979, ISSN: 0024-9297
Xuan Wei, Dong R, Dali Wang, et al., Supramolecular Fluorescent Nanoparticles Constructed via Multiple Non-Covalent Interactions for the Detection of Hydrogen Peroxide in Cancer Cells, Chemistry - A European Journal, ISSN: 0947-6539
Dong R, Zhou Y, Huang X, et al., 2015, Functional Supramolecular Polymers for Biomedical Applications, Advanced Materials, Vol: 27, Pages: 498-526, ISSN: 0935-9648
Dong R, Pang Y, Su Y, et al., 2015, Supramolecular hydrogels: synthesis, properties and their biomedical applications, Biomaterials Science, Vol: 3, Pages: 937-954, ISSN: 2047-4830
<p>The recent progress in synthesis, properties and biomedical applications of supramolecular hydrogels has been reviewed.</p>
Dong R, Zhou Y, Zhu X, 2014, Supramolecular Dendritic Polymers: From Synthesis to Applications, Accounts of Chemical Research, Vol: 47, Pages: 2006-2016, ISSN: 0001-4842
Yu S, Dong R, Chen J, et al., 2014, Synthesis and Self-Assembly of Amphiphilic Aptamer-Functionalized Hyperbranched Multiarm Copolymers for Targeted Cancer Imaging, Biomacromolecules, Vol: 15, Pages: 1828-1836, ISSN: 1525-7797
Wang D, Tong G, Dong R, et al., 2014, Self-assembly of supramolecularly engineered polymers and their biomedical applications, Chem. Commun., Vol: 50, Pages: 11994-12017, ISSN: 1359-7345
<p>Self-assembly behavior of supramolecularly engineered polymers and their biomedical applications have been summarized.</p>
Huang Y, Dong R, Zhu X, et al., 2014, Photo-responsive polymeric micelles, Soft Matter, Vol: 10, Pages: 6121-6138, ISSN: 1744-683X
<p>Photo-responsive polymeric micelles with different photo-reaction mechanisms and their applications in various fields have been discussed.</p>
Dong R, Bo Y, Tong G, et al., 2014, Self-assembly and optical properties of a porphyrin-based amphiphile, Nanoscale, Vol: 6, Pages: 4544-4550, ISSN: 2040-3364
<p>A porphyrin-based amphiphile exhibits various self-assembled morphologies and distinct optical properties in different solvents.</p>
Dong R, Zhou Y, Yan D, et al., Artificial “Jellyfish” that Breathes with Switchable Fluorescence, SINO–FRENCH WORKSHOP on Nanostructured Polymers and Nanohybrids: Towards Properties and Functions
Dong R, Zhu B, Zhou Y, et al., 2013, Reversible photoisomerization of azobenzene-containing polymeric systems driven by visible light, Polymer Chemistry, Vol: 4, Pages: 912-912, ISSN: 1759-9954
Dong R, Su Y, Yu S, et al., 2013, A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector, Chemical Communications, Vol: 49, Pages: 9845-9845, ISSN: 1359-7345
Dong R, Zhu B, Zhou Y, et al., 2012, “Breathing” Vesicles with Jellyfish-like On-Off Switchable Fluorescence Behavior, Angewandte Chemie International Edition, Vol: 51, Pages: 11633-11637, ISSN: 1433-7851
Dong R, Chen H, Wang D, et al., 2012, Supramolecular Fluorescent Nanoparticles for Targeted Cancer Imaging, ACS Macro Letters, Vol: 1, Pages: 1208-1211, ISSN: 2161-1653
Huan X, Wang D, Dong R, et al., 2012, Supramolecular ABC Miktoarm Star Terpolymer Based on Host–Guest Inclusion Complexation, Macromolecules, Vol: 45, Pages: 5941-5947, ISSN: 0024-9297
Yu S, Chen J, Dong R, et al., 2012, Enhanced gene transfection efficiency of PDMAEMA by incorporating hydrophobic hyperbranched polymer cores: effect of degree of branching, Polymer Chemistry, Vol: 3, Pages: 3324-3324, ISSN: 1759-9954
Dong R, Liu Y, Zhou Y, et al., Photo-Reversible Polymerization and Depolymerization of Supramolecular Hyperbranched Polymer through Host-Guest Interactions, 2nd Unilever–RSC International Symposium on Functional Materials Science
Dong R, Zhou L, Yan D, et al., Supramolecular Polycations Constructed by Host-Guest Interaction for Efficient Gene Delivery, 2nd Federation of Asian Polymer Societies Polymer Congress
Dong R, Zhou L, Wu J, et al., 2011, A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery, Chemical Communications, Vol: 47, Pages: 5473-5473, ISSN: 1359-7345
Dong R, Liu Y, Zhou Y, et al., 2011, Photo-reversible supramolecular hyperbranched polymer based on host–guest interactions, Polymer Chemistry, Vol: 2, Pages: 2771-2771, ISSN: 1759-9954
Liang Y, Dong R, Zhang J, et al., Investigation on the gradient solidification processing of PAN precursor during dry-jet-wet spinning, International Conference on Advanced Fibers and Polymer Materials
Dong R, Zhao J, Zhang Y, et al., 2009, Morphology control of polyacrylonitrile (PAN) fibers by phase separation technique, Journal of Polymer Science Part B: Polymer Physics, Vol: 47, Pages: 261-275, ISSN: 0887-6266
Dong R, Keuser M, Zeng X, et al., 2008, Viscometric measurement of the thermodynamics of PAN terpolymer/DMSO/water system and effect of fiber-forming conditions on the morphology of PAN precursor, Journal of Polymer Science Part B: Polymer Physics, Vol: 46, Pages: 1997-2011, ISSN: 0887-6266
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