Imperial College London


Faculty of MedicineDepartment of Medicine

Honorary Research Fellow



+44 (0)20 8816 7653r.heckemann Website




Cyclotron buildingHammersmith Campus





Medical images contain plenty of information, but some of it remains hidden on standard two-dimensional slice or surface representations. My research mission is to develop image processing methods that extract, filter and present such information in a way that makes it useful in clinical medicine as biomarkers of disease. I want to enable clinicians to see more on images of the adult human brain. This could change the lives of people with dementia symptoms: an earlier and more accurate diagnosis alleviates uncertainty and increases the hope for successful interventions. In the fight against Alzheimer disease and other dementias, biomarkers could accelerate the development of drugs that slow down or prevent disease progress, effectively improving patients' prognosis.

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Andersson KME, Wasen C, Juzokaite L, et al., 2018, Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis, Proceedings of the National Academy of Sciences of the United States of America, Vol:115, ISSN:0027-8424, Pages:E12063-E12072

Ledig C, Schuh A, Guerrero R, et al., 2018, Structural brain imaging in Alzheimer's disease and mild cognitive impairment: biomarker analysis and shared morphometry database, Scientific Reports, Vol:8, ISSN:2045-2322

Wild HM, Heckemann RA, Studholme C, et al., 2017, Gyri of the human parietal lobe: Volumes, spatial extents, automatic labelling, and probabilistic atlases, Plos One, Vol:12, ISSN:1932-6203


Prange S, Metereau E, Maillet A, et al., 2018, Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson's disease patients, International Congress of Parkinson's Disease and Movement Disorders, WILEY, Pages:S674-S674, ISSN:0885-3185

Andersson KM, Wasen C, Silfversward ST, et al., 2018, Physical functioning in rheumatoid arthritis is controlled by hippocampus and insulin-like growth factor-1 receptor signalling, TAYLOR & FRANCIS LTD, Pages:28-28, ISSN:0300-9742

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