Summary
Senior Clinical Lecturer in Anaesthetics & Intensive Care. Director of Intensive Care, Chelsea & Westminster Hospital.
MD Thesis
INTRACRANIAL PRESSURE, CEREBRAL BLOOD FLOW AND EFFECTS OF TREATMENT IN FULMINANT HEPATIC FAILURE. Awarded November 1993, University of London.
Original Papers
Forbes A, Alexander G, O’Grady J, Keays R, Gullen R, Dawling S, Williams R. Thiopental infusion in the treatment of intracranial pressure complicating fulminant hepatic failure. Hepatology 1989:10;306-310.
Harrison P, O’Grady J, Keays R, Alexander G, Williams R. Serial prothrombin times as prognostic indicator in paracetamol induced fulminant hepatic failure. Brit Med J 1990:301;964-966.
Kato M, Hughes R, Keays R, Williams R. Electron microscope study of brain capillaries in cerebral edema from fulminant hepatic failure. Hepatology 1990:12;939.
Sheron N, Goka J, Wendon J, Keays R, Alexander G, Williams R. Endotoxin and TNF levels and their relationship to prognosis in patients with fulminant hepatic failure. Hepatology 1990:12;939.
Harrison P, Keays R, Bray G, Alexander G, Williams R. Improved outcome in paracetamol-induced fulminant hepatic failure following late administration of N-acetylcysteine. Lancet 1990:335;1572-1573.
Keays R, Harrison P, Wendon J, Forbes A, Gove C, Alexander G, Williams R. Intravascular acetylcysteine in paracetamol induced fulminant hepatic liver failure: a prospective controlled trial. Brit Med J 1991:303;1026-1029.
Wendon J, Harrison P, Keays R, Gimson A, Alexander G, Williams R. Arteriovenous pH differences and tissue hypoxia in patients with fulminant hepatic failure. Crit Care Med 1991:19;1362-1364.
Keays R, Potter D, Williams R. Intracranial pressure and cerebral perfusion pressure changes before, during and after orthotopic liver transplantation for fulminant liver failure. Quart J Med 1991:289;425-433.
Langley PG, Keays R, Hughes RD, Forbes A, Delvos U, Williams R. Antithrombin III supplementation reduces heparin requirement and platelet loss during haemodialysis of patients with Fulminant Hepatic Failure. Hepatology 1991:12;331-334.
Wendon J, Harrison P, Keays R, Gimson AE, Alexander GJM, Williams R. Effects of vasopressor agents and epoprostenol on systemic hemodynamics and oxygen transport in fulminant hepatic failure. Hepatology 1992:15;1067-1071.
Keays R, Alexander GJM, Williams R. The safety and efficacy of extradural intracranial pressure monitors in fulminant hepatic failure. J Hepatol 1993:18;205-209.
Cerebral blood flow and metabolism in fulminant hepatic failure. Wendon J, Harrison P, Keays R, Williams R. Hepatology 1994:19;1407-1413.
Case Reports
Suntharalingam G, Keays R, Soni N. Acute pancreatitis. Major haemorrhage may be a late complication. Brit Med J 1998:316;1983.
Singh S, Baruah R, Ravi S, Keays R, Handy J, Hayes M, Shah P. Pneumoperitoneum secondary to complex tracheal trauma: Successful treatment with a conservative ‘protective’ ventilatory and bronchoscopic approach.
Reviews/Special Articles
Ede RJ, Keays R, Williams R. Intracranial pressure monitoring and management of encephalopathy. Care of the Critically Ill 1989, 5(2):46-48.
Keays R, Williams R. Paracetamol Poisoning. Prescribers Journal August 1989
Keays R. Cerebral Oedema in Acute Liver Failure. Current Anaesthesia and Critical Care 1998, 9(4):197-201.
Keays R. Skeletal Muscle in Critical Illness. Intensivmedizin und Notfallmedizin. 1999, 36:619-625.
Keays R, Soni N. Hepatitis and HIV infections. Anaesthesia and Intensive Care Medicine 2001;2:1:174-8
Andreyev HJN, Keays R. Post-pyloric feeding in Critical Care Patients. Current Medical Literature, Gastroenterology 2001, 20(2): 29-34.
Keays R, Soni N. HIV infections. Anaesthesia and Intensive Care Medicine 2004;5:2:54 – 57
Keays R. Hepatitis. Anaesthesia and Intensive Care Medicine 2004;5:8:283 - 5
Tillyard A, Keays R, Soni N. The diagnosis of acute renal failure in intensive care: Mongrel or Pedigree? Anaesthesia 2005, 60(9):903-14.
Vizcaychipi M, Keays R, Soni N. Anaesthesia and Intensive Care for HIV patients. Anaesthesia and Intensive Care Medicine 2007;8:2:44 – 47
Keays R. Hepatitis and CJD. Anaesthesia and Intensive Care Medicine 2007;8:2;48-51
Keays R. Therapeutic adjuncts in Sepsis. Current Anaesthesia and Critical Care 2009. doi:10.1016/j.cacc.2009.07.005
Chapters
Keays R, Soni N. Respiratory support in the Critically Ill. In: Anaesthesia and Intensive Care. 1998 R. Barrios (ed). pp 540-555
Keays R. Skeletal Muscle in Critical Illness. In: Yearbook of Intensive Care Medicine 1998. Vincent J-L (ed). pp 601-610.
Keays R. Diabetic Emergencies. In: Intensive Care Manual. Soni N, Hayes M, Oh TE (eds) – 5th Edition 2003:551-558.
Keays R. Antifungal Prophylaxis in the Immunocomprised Critically Ill Patient. In: UK Key Advances 2004. The Effective Prevention and Management of Systemic Fungal Infection (Year 2001 Update). Prentice A, Rogers T, Miles A.(eds). pp 63-76
Barret NA, Keays R. Parenteral Nutrition. In: Oxford Desk Reference Critical Care. Waldmann C, Soni N, Rhodes A (eds). Oxford University Press 2008. pp 84-5
Keays R, Barrett NA. N-Acetylcysteine. In: Oxford Desk Reference Critical Care. Waldmann C, Soni N, Rhodes A (eds). Oxford University Press 2008. pp 234-5.
Keays R. Diabetic Emergencies. In: Intensive Care Manual. Bersten A, Soni N eds) – 6th Edition 2009:613-62
Abstracts
Harrison P, Alexander G, O’Grady J, Keays R, Williams R. Serial prothrombin times and their prognostic significance in fulminant hepatic failure due to paracetamol overdose. Gut 1988:29:
Keays R, Potter D, Williams R. Intracranial pressure and cerebral perfusion pressure changes before, during and after orthotopic liver transplantation for fulminant hepatic failure. Gut 1989:30:
Keays R, Alexander G, Williams R. The safety of extradural intracranial pressure monitors in fulminant hepatic failure. Gut 1989:30:A745-6
Keays R, Alexander G, Williams R. The association of intracranial pressure with clinical signs and prognosis in fulminant hepatic failure. J Hepatol 1989: Suppl 1:194
Keays R, Gove CD, Forbes A, Alexander G, Williams R. Use of late N-acetylcysteine in fulminant hepatic failure due to paracetamol overdose. Gut 1989:30
Langley PG, Keays R, Hughes RD, Forbes A, Delvos U, Williams R. The effect of Antithrombin III supplementation on the biocompatibility of haemodialysis in patients with Fulminant Hepatic Failure. Abstracts of the British Association for the Study of the Liver 1990:March
Wendon J, Keays R, Alexander G, Williams R. The effect of inotropes and prostacyclin on oxygen delivery, oxygen consumption and oxygen extraction ratio in fulminant hepatic failure. Abstracts of the British Association for the Study of the Liver 1990:March
Publications
Journals
Tillyard A, Keays R, Soni N, 2005, The diagnosis of acute renal failure in intensive care: mongrel or pedigree?, Anaesthesia, Vol:60, ISSN:0003-2409, Pages:903-914