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@article{Carreras:2014:10.1063/1.4897495,
author = {Carreras, P and Law, RV and Brooks, NJ and Seddon, JM and Ces, O},
doi = {10.1063/1.4897495},
journal = {Biomicrofluidics},
title = {Microfluidic generation of droplet interface bilayer networks incorporating real-time size sorting in linear and non-linear configurations},
url = {http://dx.doi.org/10.1063/1.4897495},
volume = {8},
year = {2014}
}

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TY  - JOUR
AB  - In this study, a novel droplet based microfluidic method for the generation of different sized droplet interface bilayers is reported. A microfluidic platform was designed, which allows the generation and packing of picoliter lipid coated water droplets. Droplets were generated by hydrodynamic focusing coupled with selective transport along grooves according to their size. A trapping structure at the end of the groove and a fine control of the flow pressures allowed for the droplets to be successfully trapped and aligned on demand. This technology facilitates the fine control of droplet size production as well as the generation of extended networks from a variety of lipids including 1,2-diphytanoyl-sn-glycero-3- phosphocholine and 1,2-dioleoyl-sn-glycero-3-phosphocholine in linear and non- linear configurations, which is vital to the application of Droplet Interface Bilayers to biological network construction on-chip.
AU  - Carreras,P
AU  - Law,RV
AU  - Brooks,NJ
AU  - Seddon,JM
AU  - Ces,O
DO  - 10.1063/1.4897495
PY  - 2014///
SN  - 1932-1058
TI  - Microfluidic generation of droplet interface bilayer networks incorporating real-time size sorting in linear and non-linear configurations
T2  - Biomicrofluidics
UR  - http://dx.doi.org/10.1063/1.4897495
UR  - http://hdl.handle.net/10044/1/19424
VL  - 8
ER  -

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