Imperial College London

DrRogerNewson

Faculty of MedicineSchool of Public Health

Research Associate
 
 
 
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Contact

 

+44 (0)20 7594 2784r.newson Website

 
 
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Assistant

 

Mrs Pirkko Carmack +44 (0)20 7594 3368

 
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Location

 

351Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

140 results found

Shaheen SO, Newson RB, Rayman MP, Wong AP, Tumilty MK, Phillips JM, Potts JF, Kelly FJ, White PT, Burney PGet al., 2007, Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthma, Thorax, Vol: 62, Pages: 483-490, ISSN: 0040-6376

BACKGROUND: Epidemiological evidence from observational studies has suggested that blood levels and dietary intake of selenium of adults with asthma are lower than those of controls. The only previous trial of selenium supplementation in adults with asthma found no objective evidence of benefit but involved only 24 participants. METHODS: A randomised, double blind, placebo-controlled trial of selenium supplementation was performed in adults with asthma in London, UK, the majority of whom (75%) reported inhaled steroid use at baseline. 197 participants were randomised to receive either a high-selenium yeast preparation (100 microg daily, n=99) or placebo (yeast only, n=98) for 24 weeks. The primary outcome was asthma-related quality of life (QoL) score. Secondary outcomes included lung function, asthma symptom scores, peak flow and bronchodilator usage. Linear regression was used to analyse the change in outcome between the two treatment arms by ""intention to treat"". RESULTS: There was a 48% increase in plasma selenium between baseline and end of trial in the active treatment group but no change in the placebo group. While the QoL score improved more in the active treatment group than in the placebo group, the difference in change in score between the two groups was not significant (-0.05 (95% CI -0.19 to 0.09); p=0.47). Selenium supplementation was not associated with any significant improvement in secondary outcomes compared with placebo. CONCLUSIONS: Selenium supplementation had no clinical benefit in adults with asthma, the majority of whom were taking inhaled steroids.

Journal article

Glaviano A, Nayak V, Cabuy E, Baird DM, Yin Z, Newson R, Ladon D, Rubio MA, Slijepcevic P, Lyng F, Mothersill C, Case CPet al., 2006, Effects of hTERT on metal ion-induced genomic instability, ONCOGENE, Vol: 25, Pages: 3424-3435, ISSN: 0950-9232

Journal article

Newson R, 2006, Confidence intervals for rank statistics: Percentile slopes, differences, and ratios, STATA JOURNAL, Vol: 6, Pages: 497-520, ISSN: 1536-867X

Journal article

Newson R, 2006, Efficient calculation of jackknife confidence intervals for rank statistics, JOURNAL OF STATISTICAL SOFTWARE, Vol: 15, ISSN: 1548-7660

Journal article

Newson R, 2006, Confidence intervals for rank statistics: Somers' D and extensions, STATA JOURNAL, Vol: 6, Pages: 309-334, ISSN: 1536-867X

Journal article

Newson R, 2005, Efficient Calculation of Jackknife Confidence Intervals for Rank Statistics, Vol: 15

An algorithm is presented for calculating concordance-discordance totals in a time of order N log N , where N is the number of observations, using a balanced binary search tree. These totals can be used to calculate jackknife estimates and confidence limits in the same time order for a very wide range of rank statistics, including Kendall's tau, Somers' D, Harrell's c, the area under the receiver operating characteristic (ROC) curve, the Gini coefficient, and the parameters underlying the sign and rank-sum tests. A Stata package is introduced for calculating confidence intervals for these rank statistics using this algorithm, which has been implemented in the Mata compilable matrix programming language supplied with Stata.

Journal article

Davies AP, Sood A, Lewis AC, Newson R, Learmonth D, Case CPet al., 2005, Metal-specific differences in levels of DNA damage caused by synovial fluid recovered at revision arthroplasty, JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, Vol: 87B, Pages: 1439-1444, ISSN: 0301-620X

Journal article

Newson R, 2005, Review of generalized latent variable modeling by Skrondal and Rabe-Hesketh, STATA JOURNAL, Vol: 5, Pages: 130-133, ISSN: 1536-867X

Journal article

Shaheen SO, Newson RB, Henderson AJ, Headley JE, Stratton FD, Jones RW, Strachan DPet al., 2005, Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 35, Pages: 18-25, ISSN: 0954-7894

Journal article

Ladon D, Doherty A, Newson R, Turner J, Bhamra M, Case CPet al., 2004, Changes in metal levels and chromosome aberrations in the peripheral blood of patients after metal-on-metal hip arthroplasty, JOURNAL OF ARTHROPLASTY, Vol: 19, Pages: 78-83, ISSN: 0883-5403

Journal article

Newson R, 2004, Generalized power calculations for generalized linear models and more, STATA JOURNAL, Vol: 4, Pages: 379-401, ISSN: 1536-867X

Journal article

Newson R, 2004, Stata tip 13: generate and replace use the current sort order, STATA JOURNAL, Vol: 4, Pages: 484-485, ISSN: 1536-867X

Journal article

Newson RB, Shaheen SO, Henderson AJ, Emmett PM, Sherriff A, Calder PCet al., 2004, Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 114, Pages: 531-537, ISSN: 0091-6749

Journal article

Shaheen SO, Newson RB, Henderson AJ, Emmett PM, Sherriff A, Cooke Met al., 2004, Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema, EUROPEAN RESPIRATORY JOURNAL, Vol: 24, Pages: 292-297, ISSN: 0903-1936

Journal article

Newson R, 2004, Stata tip 5: Ensuring programs preserve dataset sort order, STATA JOURNAL, Vol: 4, Pages: 94-94, ISSN: 1536-867X

Journal article

Newson R, 2003, Stata tip 1: The eform() option of regress, STATA JOURNAL, Vol: 3, Pages: 445-445, ISSN: 1536-867X

Journal article

Newson R, 2003, Confidence intervals and p-values for delivery to the end user, STATA JOURNAL, Vol: 3, Pages: 245-269, ISSN: 1536-867X

Journal article

Newson R, 2003, Multiple-test procedures and smile plots, Publisher: SAGE PUBLICATIONS INC

Scholarly edition

Bernardini S, Doherty A, Newson R, Turner J, Fairman B, Bhamra M, Thomas T, Case CPet al., 2003, Increased metal levels and chromosomal aberrations in patients with metal on metal total hip replacement, 12th North American ISSX Meeting, Publisher: MARCEL DEKKER INC, Pages: 97-97, ISSN: 0360-2532

Conference paper

Shaheen SO, Newson RB, Sherriff A, Henderson AJ, Heron JE, Burney PGJ, Golding Jet al., 2002, Paracetamol use in pregnancy and wheezing in early childhood, THORAX, Vol: 57, Pages: 958-963, ISSN: 0040-6376

Journal article

Newson R, 2002, Parameters behind "nonparametric" statistics: Kendall's tau, Somers' D and median differences, STATA JOURNAL, Vol: 2, Pages: 45-64, ISSN: 1536-867X

Journal article

Neild PJ, Evans DF, Castillo FD, Newson R, Yasaki ET, Wingate DL, Gazzard BGet al., 2001, Effect of octreotide on small intestinal motility in HIV-Infected patients with chronic refractory diarrhea, DIGESTIVE DISEASES AND SCIENCES, Vol: 46, Pages: 2636-2642, ISSN: 0163-2116

Journal article

Forbes L, Harvey S, Jarvis D, Luczynska C, Newson R, Burney P, Price Jet al., 2001, Risk factors for attendance at accident and emergency departments in children with asthma living in the inner city, THORAX, Vol: 56, Pages: 21-21, ISSN: 0040-6376

Journal article

Newson R, 2001, Review of Generalized Linear Models and Extensions by Hardin and Hilbe, STATA JOURNAL, Vol: 1, Pages: 98-100, ISSN: 1536-867X

Journal article

Doherty AT, Howell RT, Ellis LA, Bisbinas I, Learmonth ID, Newson R, Case CPet al., 2001, Increased chromosome translocations and aneuploidy in peripheral blood lymphocytes of patients having revision arthroplasty of the hip, JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, Vol: 83B, Pages: 1075-1081, ISSN: 0301-620X

Journal article

Easterbrook PJ, Newson R, Ives N, Pereira S, Moyle G, Gazzard BGet al., 2001, Comparison of virologic, immunologic, and clinical response to five different initial protease inhibitor-containing and nevirapine-containing regimens, JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Vol: 27, Pages: 350-364, ISSN: 1525-4135

Journal article

Zambarakji HJ, Newson RB, Mitchell SM, 2001, CMVR diagnoses and progression of CD4 cell counts and HIV viral load measurements in HIV patients on HAART, BRITISH JOURNAL OF OPHTHALMOLOGY, Vol: 85, Pages: 837-841, ISSN: 0007-1161

Journal article

Gibbs RGJ, Newson R, Lawrenson R, Greenhalgh RM, Davies AHet al., 2001, Diagnosis and initial management of stroke and transient ischemic attack across UK health regions from 1992 to 1996 - Experience of a national primary care database, STROKE, Vol: 32, Pages: 1085-1090, ISSN: 0039-2499

Journal article

Newson R, 2001, Appropriate controls are essential in assessing the relationship between circumcision and penile dermatoses - Reply, ARCHIVES OF DERMATOLOGY, Vol: 137, Pages: 503-504, ISSN: 0003-987X

Journal article

Tachakra S, Newson R, Wootton R, Stinson Aet al., 2001, Avoiding artificiality in teleconsultations, 8th International Conference on Telemedicine and Telecare, Publisher: ROYAL SOC MEDICINE PRESS LTD, Pages: S39-S42, ISSN: 1357-633X

Conference paper

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