Imperial College London

DrRogerNewson

Faculty of MedicineSchool of Public Health

Research Associate
 
 
 
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Contact

 

+44 (0)20 7594 2784r.newson Website

 
 
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Assistant

 

Mrs Pirkko Carmack +44 (0)20 7594 3368

 
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Location

 

351Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Moore:2016:10.1016/j.chest.2016.05.038,
author = {Moore, EA and Palmer, T and Newson, R and Majeed, A and Quint, JK and Soljak, M},
doi = {10.1016/j.chest.2016.05.038},
journal = {Chest},
pages = {837--859},
title = {Pulmonary rehabilitation as a mechanism to reduce hospitalizations for acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis},
url = {http://dx.doi.org/10.1016/j.chest.2016.05.038},
volume = {150},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundAcute exacerbation of COPD (AECOPD) has a significant impact on health-care use, including physician visits and hospitalizations. Previous studies and reviews have shown that pulmonary rehabilitation (PR) has many benefits, but the effect on hospitalizations for AECOPD is inconclusive.MethodsA literature search was carried out to find studies that might help determine, using a meta-analysis, the impact of PR on AECOPD, defined as unscheduled or emergency hospitalizations and ED visits. Cohort studies and randomized controlled trials (RCTs) reporting hospitalizations for AECOPD as an outcome were included. Meta-analyses compared hospitalization rates between eligible PR recipients and nonrecipients before and after rehabilitation.ResultsEighteen studies were included in the meta-analysis. Results from 10 RCTs showed that the control groups had a higher overall rate of hospitalization than did the PR groups (control groups: 0.97 hospitalizations/patient-year; 95% CI, 0.67-1.40; PR groups: 0.62 hospitalizations/patient-year; 95% CI, 0.33-1.16). Five studies compared admission numbers in the 12 months before and after rehabilitation, finding a significantly higher admission rate before compared with after (before: 1.24 hospitalizations/patient-year; 95% CI, 0.66-2.34; after: 0.47 hospitalizations/patient-year; 95% CI, 0.28-0.79). The pooled result of three cohort studies found that the reference group had a lower admission rate compared with the PR group (0.18 hospitalizations/patient-year; 95% CI, 0.11-0.32 for reference group vs 0.28 hospitalizations/patient-year; 95% CI, 0.25-0.32 for the PR group).ConclusionsAlthough results from RCTs suggested that PR reduces subsequent admissions, pooled results from the cohort studies did not, likely reflecting the heterogeneous nature of individuals included in observational research and the varying standard of PR programs.
AU - Moore,EA
AU - Palmer,T
AU - Newson,R
AU - Majeed,A
AU - Quint,JK
AU - Soljak,M
DO - 10.1016/j.chest.2016.05.038
EP - 859
PY - 2016///
SN - 1931-3543
SP - 837
TI - Pulmonary rehabilitation as a mechanism to reduce hospitalizations for acute exacerbations of chronic obstructive pulmonary disease: A systematic review and meta-analysis
T2 - Chest
UR - http://dx.doi.org/10.1016/j.chest.2016.05.038
UR - http://hdl.handle.net/10044/1/33261
VL - 150
ER -