Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Research Associate







Mint WingSt Mary's Campus





Ryan Thwaites is a Research Associate within the Department of Respiratory Medicine of the National Heart and Lung Institute, Imperial College London. Ryan obtained his PhD in 2015 in the field of innate immunology from the Brighton and Sussex Medical School, University of Sussex. Following on from this work, he joined Professor Peter Openshaw and Professor Trevor Hansel at the NHLI.

His research continues to investigate the activity of the innate immune system in human disease, particularly during the anti-viral immune response. This work uses non-infectious human models of innate immune activation (such as Toll-like receptor agonists), experimental human infection models and natural infection. In addition to these biological interests, Ryan's work has developed non-invasive techniques for sampling the airways of infants during viral infections.



Thwaites R, A year in our understanding of COVID-19, Clinical and Experimental Immunology, ISSN:0009-9104

Habibi M, Thwaites R, Chang M, et al., 2020, Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection, Science, ISSN:0036-8075

Wiseman DJ, Thwaites RS, Openshaw PJM, 2020, A new role for CXCL4 in RSV disease., American Journal of Respiratory and Critical Care Medicine, Vol:202, ISSN:1073-449X, Pages:1-2

Jefferies K, Drysdale SB, Robinson H, et al., 2020, Presumed risk factors and biomarkers for severe respiratory syncytial virus disease and related sequelae: protocol for an observational multicenter, case-control study from the respiratory syncytial virus consortium in Europe (RESCEU)., Journal of Infectious Diseases, ISSN:0022-1899

Jha A, Thwaites RS, Tunstall T, et al., 2020, Increased nasal mucosal interferon and CCL13 response to a TLR7/8 agonist in asthma and allergic rhinitis., J Allergy Clin Immunol

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