Imperial College London

Prof. Ramon Vilar

Faculty of Natural SciencesDepartment of Chemistry

Professor of Medicinal Inorganic Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 1967r.vilar Website

 
 
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Location

 

301HMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Vilar:2016:10.1039/C6DT02880B,
author = {Vilar, Compte R and Wilson, N and Mak, LH and cilibrizzi, A and gee, AD and long, NJ and woscholski, R},
doi = {10.1039/C6DT02880B},
journal = {Dalton Transactions},
pages = {18177--18182},
title = {A lipophilic copper(II) complex as an optical probe for intracellular detection of NO},
url = {http://dx.doi.org/10.1039/C6DT02880B},
volume = {45},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A new chemical sensor for cellular imaging of NO is presented. This cell-permeable probe is based on a complex where copper(II) is coordinated to a tridentate ligand substituted with a fluorophore (NBD) and an octyl group. The fluorescent response of this complex towards a range of reactive species (namely NO, NO2-, NO3-, H2O2, ClO-, O2-and ONOO-) has been studied in vitroshowing that the probe is highly selective for NO. The probe is readily taken up by cells and is able to image the cellular concentrations of NO
AU - Vilar,Compte R
AU - Wilson,N
AU - Mak,LH
AU - cilibrizzi,A
AU - gee,AD
AU - long,NJ
AU - woscholski,R
DO - 10.1039/C6DT02880B
EP - 18182
PY - 2016///
SN - 1477-9226
SP - 18177
TI - A lipophilic copper(II) complex as an optical probe for intracellular detection of NO
T2 - Dalton Transactions
UR - http://dx.doi.org/10.1039/C6DT02880B
UR - http://hdl.handle.net/10044/1/42191
VL - 45
ER -