Imperial College London

Dr.Tobias Reichenbach

Faculty of EngineeringDepartment of Bioengineering

Reader in Sensory Neuroengineering
 
 
 
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Contact

 

+44 (0)20 7594 6370reichenbach Website

 
 
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Location

 

4.12Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Warren:2016:10.1073/pnas.1606317113,
author = {Warren, RL and Ramamoorthy, S and Ciganovic, N and Zhang, Y and Wilson, T and Petrie, T and Wang, RK and Jacques, SL and Reichenbach, JDT and Nuttall, AL and Fridberger, A},
doi = {10.1073/pnas.1606317113},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
pages = {E4304--E4310},
title = {Minimal basilar membrane motion in low-frequency hearing},
url = {http://dx.doi.org/10.1073/pnas.1606317113},
volume = {113},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Low-frequency hearing is critically important for speech and music perception, but no mechanical measurements have previously been available from inner ears with intact low-frequency parts. These regions of the cochlea may function in ways different from the extensively studied high-frequency regions, where the sensory outer hair cells produce force that greatly increases the sound-evoked vibrations of the basilar membrane. We used laser interferometry in vitro and optical coherence tomography in vivo to study the low-frequency part of the guinea pig cochlea, and found that sound stimulation caused motion of a minimal portion of the basilar membrane. Outside the region of peak movement, an exponential decline in motion amplitude occurred across the basilar membrane. The moving region had different dependence on stimulus frequency than the vibrations measured near the mechanosensitive stereocilia. This behavior differs substantially from the behavior found in the extensively studied high-frequency regions of the cochlea.
AU - Warren,RL
AU - Ramamoorthy,S
AU - Ciganovic,N
AU - Zhang,Y
AU - Wilson,T
AU - Petrie,T
AU - Wang,RK
AU - Jacques,SL
AU - Reichenbach,JDT
AU - Nuttall,AL
AU - Fridberger,A
DO - 10.1073/pnas.1606317113
EP - 4310
PY - 2016///
SN - 1091-6490
SP - 4304
TI - Minimal basilar membrane motion in low-frequency hearing
T2 - Proceedings of the National Academy of Sciences of the United States of America
UR - http://dx.doi.org/10.1073/pnas.1606317113
UR - http://hdl.handle.net/10044/1/34703
VL - 113
ER -