Imperial College London

Alex Bottle

Faculty of MedicineSchool of Public Health

Professor of Medical Statistics



+44 (0)20 7594 0913robert.bottle Website




3 Dorset Rise, London EC4Y 8ENCharing Cross HospitalCharing Cross Campus





Many of us rely on our local hospital, but how do we know if it's safe? Or better than the other one down the road? Every year we expect our healthcare system to treat more patients with more problems and to ever higher standards. We clearly need useable information on performance. The NHS benefits from huge but complex databases, and it's my job to help doctors, managers and patients make sense of them.

After secondment to the public inquiry into the crimes of GP Harold Shipman, I devised the statistical methodology behind the flagship information tool of our commercial partners, Dr Foster. With my analysis, this tool correctly identified Mid Staffordshire NHS Trust as having unacceptably high death rates and was a trigger for the national regulator to investigate. My research today continues to measure and monitor the quality of healthcare in hospital and in the community for patients with chronic disease, such as heart failure and COPD, or multimorbidity using databases such as HES and CPRD. My heart failure work was cited in the 2019 NHS Long-term Plan.

Among my teaching roles, I am the Academic Lead for my "Statistical Analysis with R for Public Health" specialisation that's now live on Coursera and is part of Imperial's online Global MPH. I am also on the Programme Board responsible for the degree's delivery. As a consultant since 2016, I train the UK public sector on statistical thinking and data analysis to improve staff effectiveness. 



Axson E, Ragutheeswaran K, Sundaram V, et al., Hospitalisation and mortality in patients with comorbid COPD and heart failure: a systematic review and meta-analysis, Respiratory Research, ISSN:1465-9921

Mula V, Parikh S, Suresh S, et al., Venous thromboembolism rates after hip and knee arthroplasty and hip fractures, Bmc Musculoskeletal Disorders, ISSN:1471-2474

Giuliani S, Honeyford K, Chang C-Y, et al., 2020, Outcomes of Primary versus Multiple-Staged Repair in Hirschsprung's Disease in England., Eur J Pediatr Surg

Spinazze P, Rykov Y, Bottle R, et al., 2019, Digital phenotyping for assessment and prediction of mental health outcomes: A scoping review protocol, Bmj Open, Vol:9, ISSN:2044-6055

Foley K, Venkatraman T, Ram B, et al., A protocol for developing a core outcomes set for evaluation of school-based physical activity interventions in primary schools, Bmj Open, ISSN:2044-6055

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