Imperial College London


Faculty of Natural SciencesDepartment of Life Sciences

Reader in Neurosciences



+44 (0)20 7594 7699s.brickley




402ASir Ernst Chain BuildingSouth Kensington Campus





My laboratory is exploring the importance of novel GABA receptor populations in the control of our sleep/wake states. We use a combination of functional recording methods and high resolution imaging techniques to study the properties of neuronal populations in different brain regions. I work closely with Bill Wisden and Nick Franks in the Biophysics Section at Imperial College.

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Ye Z, Yu X, Houston CM, et al., 2017, Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAAReceptors with Different γ Subunits., Front Cell Neurosci, Vol:11, ISSN:1662-5102

Houston CM, Diamanti E, Diamantaki M, et al., 2017, Exploring the significance of morphological diversity for cerebellar granule cell excitability, Scientific Reports, Vol:7, ISSN:2045-2322

Jager P, Ye Z, Yu X, et al., 2016, Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus, Nature Communications, Vol:7, ISSN:2041-1723

Uygun DS, Ye Z, Zecharia AY, et al., 2016, Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons, Journal of Neuroscience, Vol:36, ISSN:0270-6474, Pages:11171-11184


Wisden W, Yu X, Ye Z, et al., 2016, Histamine and gamma-amino butyric acid co-transmission promotes arousal, 23rd Congress of the European-Sleep-Research-Society, WILEY-BLACKWELL, Pages:26-26, ISSN:0962-1105

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