Dr Silvia A. Ferreira is a biomedical engineer with a background in pharmaceutical sciences (MSc 2007, University of Porto, Portugal) and nanomedicine (PhD 2012, University of Minho, Portugal). She is a post-doctoral research associate in Prof. Sara Rankin group. She collaborates with Prof. Julian Jones in the EPSRC project EP/N025059/1 “Additive manufacturing of advanced medical devices for cartilage regeneration: minimally invasive early intervention”.
She has been a postdoc in Dr Eileen Gentleman’s group at Centre for Craniofacial and Regenerative Biology, King's College London until 2018 where she focused on studying how the 3D microenvironment impacts stem cell behaviour. She is interested in how hydrogels and more recently how scaffolds direct stem cell differentiation for tissue engineering. Her work has been published in Nature Communications and Biomaterials. She is a recipient of both a Wellcome Image Award (2016) and an MIT Koch Institute Image Award (2016). During her PhD she developed nanogels to target antigen-presenting cells to be used as adjuvants and delivery systems for antigens to prevent and treat cancer.
et al., 2019, Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation, Acta Biomaterialia, Vol:89, ISSN:1742-7061, Pages:73-83
et al., 2018, An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties, Biomaterials, Vol:183, ISSN:0142-9612, Pages:102-113
et al., 2018, Bi-directional cell-pericellular matrix interactions direct stem cell fate, Nature Communications, Vol:9, ISSN:2041-1723
et al., 2018, Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence, Biomaterials, Vol:176, ISSN:0142-9612, Pages:13-23
et al., 2018, Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor-1 alpha Hydroxylase Inhibitors, Stem Cells, Vol:36, ISSN:1066-5099, Pages:1380-1392