Dr Silvia A. Ferreira is a biomedical engineer with a background in pharmaceutical sciences (MSci 2007, MRes 2011, University of Porto, Portugal), nanomedicine (PhD 2012, University of Minho, Portugal) and tissue engineering. She started her Wellcome Trust ISSF Springboard Fellowship in November 2019 at Inflammation, Repair and Development Department, at National Heart and Lung Institute.
Before, she has been Research Associate in Prof Sara Rankin group. Her research funded by EPSRC EP/N025059/1 focused on assessing the potential of 3D-printed hybrid scaffolds to drive chondrogenesis in vitro and on evaluating their biosafety and inflammatory response in vivo.
Until 2018, she has been Research Associate in Dr Eileen Gentleman’s group at Centre for Craniofacial and Regenerative Biology, King's College London where she focused on studying how the 3D microenvironment impacts stem cell behaviour and drives differentiation or quiescence. Her work funded by Wellcome Trust has been published recently in Nature Communications and Biomaterials. She has been a recipient of Wellcome Trust, MIT Koch Institute and Nature Image Awards (2016).
During her PhD she developed nanogels that target antigen-presenting cells to be used as vaccine delivery systems for antigens and adjuvants to prevent and treat cancer.
et al., 2020, Propagation phase-contrast micro-computed tomography allows laboratory-based three-dimensional imaging of articular cartilage down to the cellular level, Osteoarthritis and Cartilage, Vol:28, ISSN:1063-4584, Pages:102-111
et al., 2019, Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation, Acta Biomaterialia, Vol:89, ISSN:1742-7061, Pages:73-83
et al., 2018, An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties, Biomaterials, Vol:183, ISSN:0142-9612, Pages:102-113
et al., 2018, Bi-directional cell-pericellular matrix interactions direct stem cell fate, Nature Communications, Vol:9, ISSN:2041-1723
et al., 2018, Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence, Biomaterials, Vol:176, ISSN:0142-9612, Pages:13-23