Publications
313 results found
Radewicz K, Garey LJ, Gentleman SM, et al., 2000, Increase in HLA-DR immunoreactive microglia in frontal and temporal cortex of chronic schizophrenics, JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, Vol: 59, Pages: 137-150, ISSN: 0022-3069
- Author Web Link
- Cite
- Citations: 258
Lynch A, Gentleman SM, Hirsch SR, et al., 2000, Dendritic spine density in prefrontal cortex in schizophrenia, SCHIZOPHRENIA RESEARCH, Vol: 41, Pages: 105-105, ISSN: 0920-9964
Walsh DT, Bresciani L, Leclercq PD, et al., 2000, Intra-vitreal injection of A-β1-42 causes alterations in glial cell function in the rat retina, EUROPEAN JOURNAL OF NEUROSCIENCE, Vol: 12, Pages: 378-378, ISSN: 0953-816X
Lynch AM, Gentleman SM, Garey LJ, 2000, Dendritic spines and pyramidal cell morphology in schizophrenia, EUROPEAN JOURNAL OF NEUROSCIENCE, Vol: 12, Pages: 505-505, ISSN: 0953-816X
Bresciani LG, Walsh DT, Leclercq PD, et al., 2000, Characterisation of presenilin 1 expression in the developing rat retina, EUROPEAN JOURNAL OF NEUROSCIENCE, Vol: 12, Pages: 111-111, ISSN: 0953-816X
Royston MC, McKenzie JE, Gentleman SM, et al., 1999, Overexpression of S100β in Down's syndrome:: correlation with patient age and with β-amyloid deposition, NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol: 25, Pages: 387-393, ISSN: 0305-1846
- Author Web Link
- Cite
- Citations: 42
Chen ST, Jen A, Gentleman SM, et al., 1999, Effects of bFGF and TGFβ on the expression of amyloid precursor and B-cell lymphoma protooncogene proteins in the rat retina, NEUROREPORT, Vol: 10, Pages: 509-512, ISSN: 0959-4965
- Author Web Link
- Cite
- Citations: 8
Gentleman SM, McKenzie JE, Royston MC, et al., 1999, A comparison of manual and semi-automated methods in the assessment of axonal injury, NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol: 25, Pages: 41-47, ISSN: 0305-1846
- Author Web Link
- Cite
- Citations: 14
Graham DI, Gentleman SM, Nicoll JAR, et al., 1999, Is there a genetic basis for the deposition of β-amyloid after fatal head injury?, CELLULAR AND MOLECULAR NEUROBIOLOGY, Vol: 19, Pages: 19-30, ISSN: 0272-4340
- Author Web Link
- Cite
- Citations: 21
Griffin WST, Sheng JG, McKenzie JE, et al., 1998, Life-long overexpression of S100β in Down's syndrome:: Implications for Alzheimer pathogenesis, NEUROBIOLOGY OF AGING, Vol: 19, Pages: 401-405, ISSN: 0197-4580
- Author Web Link
- Cite
- Citations: 123
Jen LS, Hart AJ, Jen A, et al., 1998, Alzheimer's peptide kills cells in retina <i>in vivo</i>, NATURE, Vol: 392, Pages: 140-141, ISSN: 0028-0836
- Author Web Link
- Cite
- Citations: 62
Griffin WST, Sheng JG, Royston MC, et al., 1998, Glial-neuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression, BRAIN PATHOLOGY, Vol: 8, Pages: 65-72, ISSN: 1015-6305
- Author Web Link
- Cite
- Citations: 597
Leclercq PD, Garey LJ, Gentleman SM, et al., 1998, An automated position analysis of parvalbumin-immunoreactive cells in the cerebral cortex in control and schizophrenic post-mortem brain, SCHIZOPHRENIA RESEARCH, Vol: 29, Pages: 91-91, ISSN: 0920-9964
- Author Web Link
- Cite
- Citations: 1
Gentleman SM, Jamal W, Karran E, et al., 1997, Presenilin 2 immunoreactivity in the brain after fatal head injury, BRAIN PATHOLOGY, Vol: 7, Pages: 1204-1204, ISSN: 1015-6305
Graham DI, Gentleman SM, Griffin WST, et al., 1997, Apolipoprotein E immunostaining after head injury, BRAIN PATHOLOGY, Vol: 7, Pages: 1199-1199, ISSN: 1015-6305
Gentleman SM, McKenzie JE, Royston MC, et al., 1997, Quantification of diffuse axonal injury after head injury: a comparison of manual and automated procedures, BRAIN PATHOLOGY, Vol: 7, Pages: 1323-1323, ISSN: 1015-6305
Patel JI, Gentleman SM, Jen LS, et al., 1997, Nitric oxide synthase in developing retinas and after optic tract section, BRAIN RESEARCH, Vol: 761, Pages: 156-160, ISSN: 0006-8993
- Author Web Link
- Cite
- Citations: 23
Gentleman SM, Greenberg BD, Savage MJ, et al., 1997, A beta(42) is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury, NEUROREPORT, Vol: 8, Pages: 1519-1522, ISSN: 0959-4965
- Author Web Link
- Cite
- Citations: 96
Patel AJ, Jen A, Wickenden C, et al., 1997, Glia-derived cytokines and the biogenesis of amyloid plaques in Alzheimer's disease, MOLECULAR PSYCHIATRY, Vol: 2, Pages: 130-132, ISSN: 1359-4184
- Author Web Link
- Cite
- Citations: 3
Garey LJ, Kavia RBC, vonBussmann KA, et al., 1997, Serotonergic neurons in the dorsal raphe nuclei in schizophrenia, SCHIZOPHRENIA RESEARCH, Vol: 24, Pages: 38-38, ISSN: 0920-9964
- Author Web Link
- Cite
- Citations: 1
Leclercq PD, McKenzie JE, Royston MC, et al., 1997, A quantitative study of parvalbumin-immunoreactive interneurons in the cingulate gyrus of schizophrenic patients, SCHIZOPHRENIA RESEARCH, Vol: 24, Pages: 38-38, ISSN: 0920-9964
Bell JE, Gentleman SM, Ironside JW, et al., 1997, Prion protein immunocytochemistry - UK five centre consensus report, NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol: 23, Pages: 26-35, ISSN: 0305-1846
- Author Web Link
- Cite
- Citations: 100
Gentleman SM, Greenberg BD, Savage MJ, et al., 1997, Aβ<inf>42</inf> is the predominant form of amyloid β-protein in the brains of short-term survivors of head injury, NeuroReport, Vol: 8, Pages: 1519-1522, ISSN: 0959-4965
FATAL head injury results in the formation of diffuse parenchymal deposits of amyloid β-protein (Aβ) in the brains of approximately 30% of individuals. We used carboxyl terminal-specific antisera to examine the exact nature of these deposits in paraffin sections of neocortex from seven head-injured patients. Immunostaining for Aβ42 was observed in all parenchymal deposits whereas staining for Aβ40, the form of the protein which predominates in serum and cerebrospinal fluid, was seen in only a small proportion of deposits. The relative paucity of Aβ40 suggests that post-traumatic deposits do not arise as a result of passive leakage from damaged cerebral blood vessels but are similar to the early Aβ42 parenchymal deposits seen in Down's syndrome and Alzheimer's disease.
Newman SJ, Gentleman SM, 1997, Microwave antigen retrieval in formaldehyde-fixed human brain tissue., Methods Mol Biol, Vol: 72, Pages: 145-152, ISSN: 1064-3745
Gentleman S, Graham DI, 1997, Head injury and Alzheimer-type pathology: Some forensic considerations, VIIth Lubeck Workshop on Neurotraumatology - Biomechanic Aspects, Cytologic and Molecular Mechanisms, Publisher: SCHMIDT-ROMHILD, MAX, Pages: 161-171
- Author Web Link
- Cite
- Citations: 1
McKenzie KJ, McLellan DR, Gentleman SM, et al., 1996, Is β-APP a marker of axonal damage in short-surviving head injury?, Acta Neuropathologica, Vol: 92, Pages: 608-613, ISSN: 0001-6322
β-Amyloid precursor protein (β-APP), a normal constituent of neurons which is conveyed by fast axonal transport, has been found to be a useful marker for axonal damage in cases of fatal head injury. Immunocytochemistry for β-APP is a more sensitive technique for identifying axonal injury than conventional silver impregnation. This study was designed to determine how quickly evidenc of axonal damage and bulb formation appears. Using this method a variety of brain areas were studied from 55 patients who died within 24 h of a head injury. Immunocytochemical evidence of axonal injury was first detected after 2 h survival, axonal bulbs were first identified after 3 h survival, and the amount of axonal damage and axonal bulb formation increased the longer the survival time.
McKenzie KJ, McLellan DR, Gentleman SM, et al., 1996, Is beta-APP a marker of axonal damage in short-surviving head injury?, ACTA NEUROPATHOLOGICA, Vol: 92, Pages: 608-613, ISSN: 0001-6322
- Author Web Link
- Cite
- Citations: 150
Chen ST, Gentleman SM, Garey LJ, et al., 1996, Distribution of beta-amyloid precursor and B-cell lymphoma protooncogene proteins in the rat retina after optic nerve transection or vascular lesion, JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, Vol: 55, Pages: 1073-1082, ISSN: 0022-3069
- Author Web Link
- Cite
- Citations: 27
McKenzie JE, Edwards RJ, Gentleman SM, et al., 1996, A quantitative comparison of plaque types in Alzheimer's disease and senile dementia of the Lewy body type, ACTA NEUROPATHOLOGICA, Vol: 91, Pages: 526-529, ISSN: 0001-6322
- Author Web Link
- Cite
- Citations: 18
vonBussmann KA, Rodway A, Gentleman SM, et al., 1996, Decreased glutamatergic binding sites in the left orbito-frontal cortex of chronic schizophrenics, SCHIZOPHRENIA RESEARCH, Vol: 18, Pages: XB5-XB5, ISSN: 0920-9964
- Author Web Link
- Cite
- Citations: 1
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.