ProfessorSadafGhaem-Maghami

Faculty of Medicine, Department of Surgery & Cancer

Professor of Gynaecological Oncology

Contact

Location

Hammersmith HouseHammersmith HospitalHammersmith Campus

Summary

The main focus of the research group is in translational research in gynaecological cancers. In particular biomarker discovery and development (specifically immunological markers) in ovarian and endometrial cancers. The biomarkers are now in the process of being tested for diagnosis and surgical prognosis. The concept of predicting surgical outcome in ovarian cancer is a step in developing personalised medicine and providing patients with best care possible.

Recent advances in oncolgy have improved survival in patients with cancer but research into surgery may have additional benefits for the patient. Clinical research into optimal treatment of cervival preinvasive lesions has been a focus. We have shown that clear margins of resection has a significant effect on reducing risk of recurrence from preinvasive disease.

Publications

Journals

Phelps DL, Saso S, Ghaem-Maghami S, 2020, Is ovarian cancer surgery stuck in the dark ages?: a commentary piece reviewing surgical technologies, British Journal of Cancer, ISSN:0007-0920

Phelps DL, Saso S, Ghaem-Maghami S, 2020, Analysis of worldwide surgical outcomes in COVID-19-infected patients: a gynecological oncology perspective, Future Science Oa, ISSN:2056-5623, Pages:FS0629-FS0629

Tzafetas M, Mitra A, Paraskevaidi M, et al.Tzafetas M, Mitra A, Paraskevaidi M, Bodai Z, Kalliala I, Bowden S, Lathouras K, Rosini F, Szasz M, Savage A, Manoli E, Balog J, McKenzie J, Lyons D, Bennett P, MacIntyre D, Ghaem-Maghami S, Takats Z, Kyrgiou M close, 2020, The intelligent knife (iKnife) and its intraoperative diagnostic advantage for the treatment of cervical disease (vol 117, pg 7338, 2020), Proceedings of the National Academy of Sciences of the United States of America, Vol:117, ISSN:0027-8424, Pages:18892-18892

Natoli M, Bonito N, Robinson JD, et al.Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y close, 2020, Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade, Cancer Immunology Immunotherapy, Vol:69, ISSN:0340-7004, Pages:1391-1401

Natoli M, Bonito N, Robinson JD, et al.Natoli M, Bonito N, Robinson JD, Ghaem-Maghami S, Mao Y close, 2020, Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade (vol 45, pg 203, 2020), Cancer Immunology Immunotherapy, Vol:69, ISSN:0340-7004, Pages:1403-1408

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