Summary
The main focus of the research group is in translational research in gynaecological cancers. In particular biomarker discovery and development (specifically immunological markers) in ovarian and endometrial cancers. The biomarkers are now in the process of being tested for diagnosis and surgical prognosis. The concept of predicting surgical outcome in ovarian cancer is a step in developing personalised medicine and providing patients with best care possible.
Recent advances in oncolgy have improved survival in patients with cancer but research into surgery may have additional benefits for the patient. Clinical research into optimal treatment of cervival preinvasive lesions has been a focus. We have shown that clear margins of resection has a significant effect on reducing risk of recurrence from preinvasive disease.
Publications
Journals
Barcroft JF, Galazis N, Jones BP, et al., 2021, Fertility treatment and cancers-the eternal conundrum: a systematic review and meta-analysis., Human Reproduction, Vol:36, ISSN:0268-1161, Pages:1093-1107
Saso S, Ahmed-Salim Y, Meehan H, et al., 2021, A Novel Application of Calcium Electroporation to Cutaneous Manifestations of Gynaecological Cancer, European Journal of Gynecological Oncology, ISSN:0392-2936
Sundar S, Manchanda R, Gourley C, et al., 2021, British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for BRCA1/2 variants in ovarian cancer in the United Kingdom, International Journal of Gynecological Cancer, Vol:31, ISSN:1048-891X, Pages:272-278
Jones BP, Rajamanoharan A, Vali S, et al., 2021, Perceptions and Motivations for Uterus Transplant in Transgender Women, Jama Network Open, Vol:4, ISSN:2574-3805
Natoli M, Gallon J, Lu H, et al., 2021, Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression, Journal for Immunotherapy of Cancer, Vol:9, ISSN:2051-1426