Imperial College London

Dr Sophie Helaine

Faculty of MedicineDepartment of Medicine

Senior Lecturer



+44 (0)20 7594 3976s.helaine




2.20Flowers buildingSouth Kensington Campus






BibTex format

author = {Fisher, RA and Cheverton, AM and Helaine, S},
doi = {10.1007/978-1-4939-2854-5_15},
journal = {Methods Mol Biol},
pages = {177--187},
title = {Analysis of Macrophage-Induced Salmonella Persisters.},
url = {},
volume = {1333},
year = {2016}

RIS format (EndNote, RefMan)

AB - A small subpopulation of non-replicating, multidrug-tolerant bacteria is present within clonal populations of many bacterial species. Known as persisters, these bacteria are probably the cause of relapsing infections such as typhoid fever. Formation of non-growing Salmonella persisters is stimulated by macrophage phagocytosis. This chapter outlines methods to identify and study persisters resulting from interactions between bacterial pathogens and their hosts. We use their antibiotic tolerance for isolation and enumeration and developed a method to study the heterogeneity of growth within clonal populations through single-cell analysis.
AU - Fisher,RA
AU - Cheverton,AM
AU - Helaine,S
DO - 10.1007/978-1-4939-2854-5_15
EP - 187
PY - 2016///
SP - 177
TI - Analysis of Macrophage-Induced Salmonella Persisters.
T2 - Methods Mol Biol
UR -
UR -
VL - 1333
ER -