Imperial College London

Prof Steve Matthews

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Chemical and Structural Biology
 
 
 
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Contact

 

+44 (0)20 7594 5315s.j.matthews Website

 
 
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Location

 

602Sir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

203 results found

Cowper B, Matthews S, Tomley F, 2012, The molecular basis for the distinct host and tissue tropisms of coccidian parasites, MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Vol: 186, Pages: 1-10, ISSN: 0166-6851

JOURNAL ARTICLE

Garnett JA, Martinez-Santos VI, Saldana Z, Pape T, Hawthorne W, Chan J, Simpson PJ, Cota E, Puente JL, Giron JA, Matthews Set al., 2012, Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 109, Pages: 3950-3955, ISSN: 0027-8424

JOURNAL ARTICLE

Garnett JA, Matthews S, 2012, Interactions in Bacterial Biofilm Development: A Structural Perspective, CURRENT PROTEIN & PEPTIDE SCIENCE, Vol: 13, Pages: 739-755, ISSN: 1389-2037

JOURNAL ARTICLE

Garnett JA, Simpson PJ, Taylor J, Benjamin SV, Tagliaferri C, Cota E, Chen Y-YM, Wu H, Matthews Set al., 2012, Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 417, Pages: 421-426, ISSN: 0006-291X

JOURNAL ARTICLE

Hughes S, Elustondo F, Di Fonzo A, Leroux FG, Wong AC, Snijders AP, Matthews SJ, Cherepanov Pet al., 2012, Crystal structure of human CDC7 kinase in complex with its activator DBF4, NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol: 19, Pages: 1101-+, ISSN: 1545-9993

JOURNAL ARTICLE

James E, Liu M, Sheppard C, Mekler V, Camara B, Liu B, Simpson P, Cota E, Severinov K, Matthews S, Wigneshweraraj Set al., 2012, Structural and Mechanistic Basis for the Inhibition of Escherichia coli RNA Polymerase by T7 Gp2, MOLECULAR CELL, Vol: 47, Pages: 755-766, ISSN: 1097-2765

JOURNAL ARTICLE

Liu B, Garnett JA, Lee W-C, Lin J, Salgado P, Taylor J, Xu Y, Lambert S, Cota E, Matthews Set al., 2012, Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 421, Pages: 208-213, ISSN: 0006-291X

JOURNAL ARTICLE

Marchant J, Cowper B, Liu Y, Lai L, Pinzan C, Marq JB, Friedrich N, Sawmynaden K, Liew L, Chai W, Childs RA, Saouros S, Simpson P, Barreira MCR, Feizi T, Soldati-Favre D, Matthews Set al., 2012, Galactose recognition by the apicomplexan parasite Toxoplasma gondii. (vol 287, pg 16720, 2012), JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 287, Pages: 31455-31455, ISSN: 0021-9258

JOURNAL ARTICLE

Marchant J, Cowper B, Liu Y, Lai L, Pinzan C, Marq JB, Friedrich N, Sawmynaden K, Liew L, Chai W, Childs RA, Saouros S, Simpson P, Roque Barreira MC, Feizi T, Soldati-Favre D, Matthews Set al., 2012, Galactose Recognition by the Apicomplexan Parasite Toxoplasma gondii, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 287, Pages: 16720-16733, ISSN: 0021-9258

JOURNAL ARTICLE

Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian L-Y, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama Set al., 2012, In support of the BMRB., Nat Struct Mol Biol, Vol: 19, Pages: 854-860

JOURNAL ARTICLE

Saouros S, Dou Z, Henry M, Marchant J, Carruthers VB, Matthews Set al., 2012, Microneme Protein 5 Regulates the Activity of Toxoplasma Subtilisin 1 by Mimicking a Subtilisin Prodomain, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 287, Pages: 36029-36040, ISSN: 0021-9258

JOURNAL ARTICLE

Shadrin A, Sheppard C, Severinov K, Matthews S, Wigneshweraraj Set al., 2012, Substitutions in the Escherichia coli RNA polymerase inhibitor T7 Gp2 that allow inhibition of transcription when the primary interaction interface between Gp2 and RNA polymerase becomes compromised, MICROBIOLOGY-SGM, Vol: 158, Pages: 2753-2764, ISSN: 1350-0872

JOURNAL ARTICLE

Spear AM, Rana RR, Jenner DC, Flick-Smith HC, Oyston PCF, Simpson P, Matthews SJ, Byrne B, Atkins HSet al., 2012, A Toll/interleukin (IL)-1 receptor domain protein from Yersinia pestis interacts with mammalian IL-1/Toll-like receptor pathways but does not play a central role in the virulence of Y. pestis in a mouse model of bubonic plague, MICROBIOLOGY-SGM, Vol: 158, Pages: 1593-1606, ISSN: 1350-0872

JOURNAL ARTICLE

Teo I, Toms SM, Marteyn B, Barata TS, Simpson P, Johnston KA, Schnupf P, Puhar A, Bell T, Tang C, Zloh M, Matthews S, Rendle PM, Sansonetti PJ, Shaunak Set al., 2012, Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers, EMBO MOLECULAR MEDICINE, Vol: 4, Pages: 866-881, ISSN: 1757-4676

JOURNAL ARTICLE

Garnett JA, Ramboarina S, Lee W-C, Tagliaferri C, Wu W, Matthews Set al., 2011, Crystallization and initial crystallographic analysis of the Streptococcus parasanguinis FW213 Fap1-NR alpha adhesive domain at pH 5.0, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, Vol: 67, Pages: 274-276, ISSN: 1744-3091

JOURNAL ARTICLE

Joshi A, Coelho MB, Kotik-Kogan O, Simpson PJ, Matthews SJ, Smith CWJ, Curry Set al., 2011, Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing, STRUCTURE, Vol: 19, Pages: 1816-1825, ISSN: 0969-2126

JOURNAL ARTICLE

Lai L, Bumstead J, Liu Y, Garnett J, Campanero-Rhodes MA, Blake DP, Palma AS, Chai W, Ferguson DJP, Simpson P, Feizi T, Tomley FM, Matthews Set al., 2011, The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella, PLOS PATHOGENS, Vol: 7, ISSN: 1553-7366

JOURNAL ARTICLE

Moore B, Miles AJ, Guerra-Giraldez C, Simpson P, Iwata M, Wallace BA, Matthews SJ, Smith DF, Brown KAet al., 2011, Structural Basis of Molecular Recognition of the Leishmania Small Hydrophilic Endoplasmic Reticulum-associated Protein (SHERP) at Membrane Surfaces, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 286, Pages: 9246-9256, ISSN: 0021-9258

JOURNAL ARTICLE

Rana RR, Simpson P, Zhang M, Jennions M, Ukegbu C, Spear AM, Alguel Y, Matthews SJ, Atkins HS, Byrne Bet al., 2011, Yersinia pestis TIR-domain protein forms dimers that interact with the human adaptor protein MyD88, MICROBIAL PATHOGENESIS, Vol: 51, Pages: 89-95, ISSN: 0882-4010

JOURNAL ARTICLE

Salgado PS, Taylor JD, Cota E, Matthews SJet al., 2011, Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, Vol: 67, Pages: 8-13, ISSN: 0907-4449

JOURNAL ARTICLE

Salgado PS, Yan R, Taylor JD, Burchell L, Jones R, Hoyer LL, Matthews SJ, Simpson PJ, Cota Eet al., 2011, Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 108, Pages: 15775-15779, ISSN: 0027-8424

JOURNAL ARTICLE

Sheppard C, Camara B, Shadrin A, Akulenko N, Liu M, Baldwin G, Severinov K, Cota E, Matthews S, Wigneshweraraj SRet al., 2011, Reprint of: Inhibition of Escherichia coli RNAp by T7 Gp2 protein: Role of Negatively Charged Strip of Amino Acid Residues in Gp2, JOURNAL OF MOLECULAR BIOLOGY, Vol: 412, Pages: 832-841, ISSN: 0022-2836

JOURNAL ARTICLE

Sheppard C, Camara B, Shadrin A, Akulenko N, Lu M, Baldwin G, Severinov K, Cota E, Matthews S, Wigneshweraraj SRet al., 2011, Inhibition of Escherichia coli RNAp by T7 Gp2 Protein: Role of Negatively Charged Strip of Amino Acid Residues in Gp2, JOURNAL OF MOLECULAR BIOLOGY, Vol: 407, Pages: 623-632, ISSN: 0022-2836

JOURNAL ARTICLE

Taylor JD, Zhou Y, Salgado PS, Patwardhan A, McGuffie M, Pape T, Grabe G, Ashman E, Constable SC, Simpson PJ, Lee W-C, Cota E, Chapman MR, Matthews SJet al., 2011, Atomic Resolution Insights into Curli Fiber Biogenesis, STRUCTURE, Vol: 19, Pages: 1307-1316, ISSN: 0969-2126

JOURNAL ARTICLE

Woermann ME, Corrigan RM, Simpson PJ, Matthews SJ, Gruendling Aet al., 2011, Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes, MOLECULAR MICROBIOLOGY, Vol: 79, Pages: 566-583, ISSN: 0950-382X

JOURNAL ARTICLE

Yang Y, Berry AA, Lee W-C, Garnett JA, Marchant J, Levine JA, Simpson PJ, Fogel SA, Varney KM, Matthews SJ, Nataro JP, Inman KGet al., 2011, Complete H-1, C-13 and N-15 NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli, BIOMOLECULAR NMR ASSIGNMENTS, Vol: 5, Pages: 1-5, ISSN: 1874-2718

JOURNAL ARTICLE

Yang Y, Garnett JA, Matthews S, 2011, Crystallization and initial crystallographic analysis of AafA: the major adhesive subunit of the enteroaggregative Escherichia coli AAF/II pilus, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, Vol: 67, Pages: 454-456, ISSN: 1744-3091

JOURNAL ARTICLE

Yu X-J, Liu M, Matthews S, Holden DWet al., 2011, Tandem Translation Generates a Chaperone for the Salmonella Type III Secretion System Protein SsaQ, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 286, Pages: 36098-36107, ISSN: 0021-9258

JOURNAL ARTICLE

Arbeloa A, Garnett J, Lillington J, Bulgin RR, Berger CN, Lea SM, Matthews S, Frankel Get al., 2010, EspM2 is a RhoA guanine nucleotide exchange factor, CELLULAR MICROBIOLOGY, Vol: 12, Pages: 654-664, ISSN: 1462-5814

JOURNAL ARTICLE

Bergeron JRC, Huthoff H, Veselkov DA, Beavil RL, Simpson PJ, Matthews SJ, Malim MH, Sanderson MRet al., 2010, The SOCS-Box of HIV-1 Vif Interacts with ElonginBC by Induced-Folding to Recruit Its Cul5-Containing Ubiquitin Ligase Complex, PLOS PATHOGENS, Vol: 6, ISSN: 1553-7366

JOURNAL ARTICLE

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