Imperial College London

ProfessorSebastianJohnston

Faculty of MedicineNational Heart & Lung Institute

Asthma UK Clinical Chair
 
 
 
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Contact

 

+44 (0)20 7594 3764s.johnston

 
 
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Assistant

 

Mr Christophe Tytgat +44 (0)20 7594 3849

 
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Location

 

343Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

470 results found

Girkin J, Hatchwell L, Foster P, Johnston SL, Bartlett N, Collison A, Mattes Jet al., 2015, CCL7 and IRF-7 Mediate Hallmark Inflammatory and IFN Responses following Rhinovirus 1B Infection, JOURNAL OF IMMUNOLOGY, Vol: 194, Pages: 4924-4930, ISSN: 0022-1767

JOURNAL ARTICLE

Jackson DJ, Glanville N, Trujillo-Torralbo M-B, Shamji BWH, del-Rosario J, Mallia P, Edwards MJ, Walton RP, Edwards MR, Johnston SLet al., 2015, Interleukin-18 Is Associated With Protection Against Rhinovirus-Induced Colds and Asthma Exacerbations, CLINICAL INFECTIOUS DISEASES, Vol: 60, Pages: 1528-1531, ISSN: 1058-4838

JOURNAL ARTICLE

Teo SM, Mok D, Pham K, Kusel M, Serralha M, Troy N, Holt BJ, Hales BJ, Walker ML, Hollams E, Bochkov YA, Grindle K, Johnston SL, Gern JE, Sly PD, Holt PG, Holt KE, Inouye Met al., 2015, The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development, CELL HOST & MICROBE, Vol: 17, Pages: 704-715, ISSN: 1931-3128

JOURNAL ARTICLE

Glanville N, Johnston SL, 2015, Challenges in developing a cross-serotype rhinovirus vaccine, CURRENT OPINION IN VIROLOGY, Vol: 11, Pages: 83-88, ISSN: 1879-6257

JOURNAL ARTICLE

Bonnelykke K, Vissing NH, Sevelsted A, Johnston SL, Bisgaard Het al., 2015, Association between respiratory infections in early life and later asthma is independent of virus type, ALERGOLOGIA POLSKA-POLISH JOURNAL OF ALLERGOLOGY, Vol: 2, Pages: T25-T35, ISSN: 2353-3854

JOURNAL ARTICLE

Schapowal A, Klein P, Johnston SL, 2015, Echinacea Reduces the Risk of Recurrent Respiratory Tract Infections and Complications: A Meta-Analysis of Randomized Controlled Trials, ADVANCES IN THERAPY, Vol: 32, Pages: 187-200, ISSN: 0741-238X

JOURNAL ARTICLE

Cameron A, Dhariwal J, Johnston SL, Walton RPet al., 2015, Rhinovirus Modulation of Dendritic Cell Phenotype and Function, Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Publisher: MOSBY-ELSEVIER, Pages: AB63-AB63, ISSN: 0091-6749

CONFERENCE PAPER

Lan F, Zhang N, Holtappels G, De Ruyck N, Papadopoulos NG, Johnston SL, Bachert Cet al., 2015, Staphyloccoccus Aureus Induces a Th2 Response Via TSLP and IL-33 Release in Human Airway Mucosa, Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Publisher: MOSBY-ELSEVIER, Pages: AB81-AB81, ISSN: 0091-6749

CONFERENCE PAPER

Drysdale SB, Alcazar-Paris M, Wilson T, Smith M, Zuckerman M, Peacock JL, Johnston SL, Greenough Aet al., 2015, Viral lower respiratory tract infections and preterm infants' healthcare utilisation, EUROPEAN JOURNAL OF PEDIATRICS, Vol: 174, Pages: 209-215, ISSN: 0340-6199

JOURNAL ARTICLE

Schogler A, Kopf BS, Edwards MR, Johnston SL, Casaultal C, Kieninger E, Jung A, Moeller A, Geiser T, Regamey N, Alves MPet al., 2015, Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells, EUROPEAN RESPIRATORY JOURNAL, Vol: 45, Pages: 428-439, ISSN: 0903-1936

JOURNAL ARTICLE

Zdrenghea MT, Makrinioti H, Muresan A, Johnston SL, Stanciu LAet al., 2015, The role of macrophage IL-10/innate IFN interplay during virus-induced asthma, REVIEWS IN MEDICAL VIROLOGY, Vol: 25, Pages: 33-49, ISSN: 1052-9276

JOURNAL ARTICLE

Niespodziana K, Cabauatan CR, Jackson DJ, Gallerano D, Trujillo-Torralbo B, del Rosario A, Mallia P, Valenta R, Johnston SLet al., 2015, Rhinovirus-induced VP1-specific Antibodies are Group-specific and Associated With Severity of Respiratory Symptoms, EBIOMEDICINE, Vol: 2, Pages: 64-70, ISSN: 2352-3964

JOURNAL ARTICLE

Toussaint M, Footitt J, Trujillo-Torralbo M-B, Kebadze T, Aniscenko J, Del Rosario A, Adcock IM, Johnston SL, Mallia Pet al., 2015, Airway Dna Levels In Virus-Induced COPD Exacerbations, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X

CONFERENCE PAPER

Calderazzo M, Trujillo-Torralbo M, Finney LJ, Kebadze T, Johnston SL, Mallia Pet al., 2015, Relationship Between Viral Colds And COPD Exacerbations, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X

CONFERENCE PAPER

Almond MH, Bakhsoliani E, Edwards MR, Barclay WS, Johnston SLet al., 2015, Obesity Is Associated With Decreased Expression Of Suppressor Of Cytokine Signalling 3 In Human Alveolar Macrophages, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X

CONFERENCE PAPER

Hilzendeger C, Da Silva J, Henket M, Moermans C, Corhay J-L, Edwards M, Johnston SL, Louis Ret al., 2015, Expression Of Interferons And Interferon-Stimulated Genes In Peripheral-Blood Neutrophils From COPD Patients, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X

CONFERENCE PAPER

Singanayagam A, Johnston SL, Mallia P, 2015, Inhaled Glucocorticoids and COPD Exacerbations, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 372, Pages: 92-93, ISSN: 0028-4793

JOURNAL ARTICLE

Bartlett NW, Singanayagam A, Johnston SL, 2015, Mouse models of rhinovirus infection and airways disease., Methods Mol Biol, Vol: 1221, Pages: 181-188

Mouse models are invaluable tools for gaining insight into host immunity during virus infection. Until recently, no practical mouse model for rhinovirus infection was available. Development of infection models was complicated by the existence of distinct groups of viruses that utilize different host cell surface proteins for binding and entry. Here, we describe mouse infection models, including virus purification and measurement of host immune responses, for representative viruses from two of these groups: (1) infection of unmodified Balb/c mice with minor group rhinovirus serotype 1B (RV-1B) and (2) infection of transgenic Balb/c mice with major group rhinovirus serotype 16 (RV-16).

JOURNAL ARTICLE

Jackson DJ, Makrinioti H, Rana BMJ, Shamji BWH, Trujillo-Torralbo M-B, Footitt J, Del-Rosario J, Telcian AG, Nikonova A, Zhu J, Aniscenko J, Gogsadze L, Bakhsoliani E, Traub S, Dhariwal J, Porter J, Hunt D, Hunt T, Hunt T, Stanciu LA, Khaitov M, Bartlett NW, Edwards MR, Kon OM, Mallia P, Papadopoulos NG, Akdis CA, Westwick J, Edwards MJ, Cousins DJ, Walton RP, Johnston SLet al., 2014, IL-33-Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 190, Pages: 1373-1382, ISSN: 1073-449X

JOURNAL ARTICLE

Finney L, Berry M, Singanayagam A, Elkin SL, Johnston SL, Mallia Pet al., 2014, Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 919-932, ISSN: 2213-2600

JOURNAL ARTICLE

Drysdale SB, Lo J, Prendergast M, Alcazar M, Wilson T, Zuckerman M, Smith M, Broughton S, Rafferty GF, Peacock JL, Johnston SL, Greenough Aet al., 2014, Lung function of preterm infants before and after viral infections, EUROPEAN JOURNAL OF PEDIATRICS, Vol: 173, Pages: 1497-1504, ISSN: 0340-6199

JOURNAL ARTICLE

Molyneaux PL, Cox MJ, Willis-Owen SAG, Mallia P, Russell KE, Russel A-M, Murphy E, Johnston SL, Schwarte DA, Wells AU, Cookson WOC, Maher TM, Moffatt MFet al., 2014, The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 190, Pages: 906-913, ISSN: 1073-449X

JOURNAL ARTICLE

Beale J, Jayaraman A, Jackson DJ, Macintyre JDR, Edwards MR, Walton RP, Zhu J, Ching YM, Shamji B, Edwards M, Westwick J, Cousins DJ, Hwang YY, McKenzie A, Johnston SL, Bartlett NWet al., 2014, Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation, SCIENCE TRANSLATIONAL MEDICINE, Vol: 6, ISSN: 1946-6234

JOURNAL ARTICLE

Mousnier A, Swieboda D, Pinto A, Guedan A, Rogers AV, Walton R, Johnston SL, Solari Ret al., 2014, Human Rhinovirus 16 Causes Golgi Apparatus Fragmentation without Blocking Protein Secretion, JOURNAL OF VIROLOGY, Vol: 88, Pages: 11671-11685, ISSN: 0022-538X

JOURNAL ARTICLE

Tsoumakidou M, Tousa S, Semitekolou M, Panagiotou P, Panagiotou A, Morianos I, Litsiou E, Trochoutsou AI, Konstantinou M, Potaris K, Footitt J, Mallia P, Zakynthinos S, Johnston SL, Xanthou Get al., 2014, Tolerogenic signaling by pulmonary CD1c(+) dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 134, Pages: 944-U282, ISSN: 0091-6749

JOURNAL ARTICLE

Jayaraman A, Jackson DJ, Message SD, Pearson RM, Aniscenko J, Caramori G, Mallia P, Papi A, Shamji B, Edwards M, Westwick J, Hansel T, Stanciu LA, Johnston SL, Bartlett NWet al., 2014, IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection, Publisher: NATURE PUBLISHING GROUP

WORKING PAPER

Lan F, Zhang N, Wang DX, Krysko O, Holtappels G, Papadopoulos NG, Johnston SL, Bachert Cet al., 2014, Staphyloccoccus aureus elicit epithelial cell-derived cytokine productions in human nasal tissue, European-Academy-of-Allergy-and-Clinical-Immunology Congress, Publisher: WILEY-BLACKWELL, Pages: 169-169, ISSN: 0105-4538

CONFERENCE PAPER

Wolsk HM, Folsgaard N, Birch S, Brix S, Hansel TT, Johnston SL, Kebadze T, Chawes BL, Bonnelykke K, Bisgaard Het al., 2014, The presence of viruses alters the immune signature in the airway of asymptomatic neonates, European-Academy-of-Allergy-and-Clinical-Immunology Congress, Publisher: WILEY-BLACKWELL, Pages: 192-193, ISSN: 0105-4538

CONFERENCE PAPER

Nikonova A, Jackson D, Traub S, Johnston SL, Khaitov M, Stanciu LAet al., 2014, Changes in peripheral blood monocytes, B-cells, myeloid and plasmacytoid dendritic cells in asthma patients during rhinovirus-induced exacerbation, European-Academy-of-Allergy-and-Clinical-Immunology Congress, Publisher: WILEY-BLACKWELL, Pages: 147-147, ISSN: 0105-4538

CONFERENCE PAPER

Bousquet J, Addis A, Adcock I, Agache I, Agusti A, Alonso A, Annesi-Maesano I, Anto JM, Bachert C, Baena-Cagnani CE, Bai C, Baigenzhin A, Barbara C, Barnes PJ, Bateman ED, Beck L, Bedbrook A, Bel EH, Benezet O, Bennoor KS, Benson M, Bernabeu-Wittel M, Bewick M, Bindslev-Jensen C, Blain H, Blasi F, Bonini M, Bonini S, Boulet LP, Bourdin A, Bourret R, Bousquet PJ, Brightling CE, Briggs A, Brozek J, Buhl R, Bush A, Caimmi D, Calderon M, Calverley P, Camargos PA, Camuzat T, Canonica GW, Carlsen KH, Casale TB, Cazzola M, Sarabia AMC, Cesario A, Chen YZ, Chkhartishvili E, Chavannes NH, Chiron R, Chuchalin A, Chung KF, Cox L, Crooks G, Crooks MG, Cruz AA, Custovic A, Dahl R, Dahlen SE, De Blay F, Dedeu T, Deleanu D, Demoly P, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dubakiene R, Eglin S, Elliot F, Emuzyte R, Fabbri L, Wagner AF, Fletcher M, Fokkens WJ, Fonseca J, Franco A, Frith P, Furber A, Gaga M, Garces J, Garcia-Aymerich J, Gamkrelidze A, Gonzales-Diaz S, Gouzi F, Guzman MA, Haahtela T, Harrison D, Hayot M, Heaney LG, Heinrich J, Hellings PW, Hooper J, Humbert M, Hyland M, Iaccarino G, Jakovenko D, Jardim JR, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Joos G, Jung KS, Kalayci O, Karunanithi S, Keil T, Khaltaev N, Kolek V, Kowalski ML, Kull I, Kuna P, Kvedariene V, Le LT, Carlsen KCL, Louis R, MacNee W, Mair A, Majer I, Manning P, Keenoy EDM, Masjedi MR, Meten E, Melo-Gomes E, Menzies-Gow A, Mercier G, Mercier J, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, N'Diaye M, Nafti S, Nekam K, Neou A, Nicod L, O'Hehir R, Ohta K, Paggiaro P, Palkonen S, Palmer S, Papadopoulos NG, Papi A, Passalacqua G, Pavord I, Pigearias B, Plavec D, Postma DS, Price D, Rabe KF, Pontal FR, Redon J, Rennard S, Roberts J, Robine JM, Roca J, Roche N, Rodenas F, Roggeri A, Rolland C, Rosado-Pinto J, Ryan D, Samolinski B, Sanchez-Borges M, Schunemann HJ, Sheikh A, Shields M, Siafakas N, Sibilleet al., 2014, Integrated care pathways for airway diseases (AIRWAYS-ICPs), EUROPEAN RESPIRATORY JOURNAL, Vol: 44, Pages: 304-323, ISSN: 0903-1936

JOURNAL ARTICLE

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