Imperial College London

ProfessorSebastianJohnston

Faculty of MedicineNational Heart & Lung Institute

Asthma UK Clinical Chair
 
 
 
//

Contact

 

+44 (0)20 7594 3764s.johnston

 
 
//

Assistant

 

Mr Christophe Tytgat +44 (0)20 7594 3849

 
//

Location

 

343Norfolk PlaceSt Mary's Campus

//

Summary

 

Publications

Publication Type
Year
to

471 results found

Wong EHC, Porter JD, Edwards MR, Johnston SLet al., 2014, The role of macrolides in asthma: current evidence and future directions, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 657-670, ISSN: 2213-2600

JOURNAL ARTICLE

Ic-Jusufagic AS, Belgrave D, Pickles A, Telcian AG, Bakhsoliani E, Sykes A, Simpson A, Johnston SL, Custovic Aet al., 2014, Assessing the association of early life antibiotic prescription with asthma exacerbations, impaired antiviral immunity, and genetic variants in 17q21: a population-based birth cohort study, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 621-630, ISSN: 2213-2600

JOURNAL ARTICLE

Djukanovic R, Harrison T, Johnston SL, Gabbay F, Wark P, Thomson NC, Niven R, Singh D, Reddel HK, Davies DE, Marsden R, Boxall C, Dudley S, Plagnol V, Holgate ST, Monk Pet al., 2014, The Effect of Inhaled IFN-beta on Worsening of Asthma Symptoms Caused by Viral Infections A Randomized Trial, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 190, Pages: 145-154, ISSN: 1073-449X

JOURNAL ARTICLE

Drysdale SB, Alcazar M, Wilson T, Smith M, Zuckerman M, Lauinger IL, Tong CYW, Broughton S, Rafferty GF, Johnston SL, Greenough Aet al., 2014, Respiratory outcome of prematurely born infants following human rhinovirus A and C infections, EUROPEAN JOURNAL OF PEDIATRICS, Vol: 173, Pages: 913-919, ISSN: 0340-6199

JOURNAL ARTICLE

Khaitov MR, Shilovskiy IP, Nikonova AA, Shershakova NN, Kamyshnikov OY, Babakhin AA, Zverev VV, Johnston SL, Khaitov RMet al., 2014, Small Interfering RNAs Targeted to Interleukin-4 and Respiratory Syncytial Virus Reduce Airway Inflammation in a Mouse Model of Virus-Induced Asthma Exacerbation, HUMAN GENE THERAPY, Vol: 25, Pages: 642-650, ISSN: 1043-0342

JOURNAL ARTICLE

Telcian AG, Zdrenghea MT, Caramori G, Laza-Stanca V, Message SD, Kebadze T, Kon OM, Groh V, Papi A, Johnston SL, Mallia P, Stanciu LAet al., 2014, Soluble Major Histocompatibility Complex Class I-Related Chain B Molecules Are Increased and Correlate With Clinical Outcomes During Rhinovirus Infection in Healthy Subjects, CHEST, Vol: 146, Pages: 32-40, ISSN: 0012-3692

JOURNAL ARTICLE

Rohde G, Message SD, Haas JJ, Kebadze T, Parker H, Laza-Stanca V, Khaitov MR, Kon OM, Stanciu LA, Mallia P, Edwards MR, Johnston SLet al., 2014, CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 44, Pages: 930-939, ISSN: 0954-7894

JOURNAL ARTICLE

Drysdale SB, Prendergast M, Alcazar M, Wilson T, Smith M, Zuckerman M, Broughton S, Rafferty GF, Johnston SL, Hodemaekers HM, Janssen R, Bont L, Greenough Aet al., 2014, Genetic predisposition of RSV infection-related respiratory morbidity in preterm infants, EUROPEAN JOURNAL OF PEDIATRICS, Vol: 173, Pages: 905-912, ISSN: 0340-6199

JOURNAL ARTICLE

Zhu J, Message SD, Qiu Y, Mallia P, Kebadze T, Contoli M, Ward CK, Barnathan ES, Mascelli MA, Kon OM, Papi A, Stanciu LA, Jeffery PK, Johnston SLet al., 2014, Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma, CHEST, Vol: 145, Pages: 1219-1229, ISSN: 0012-3692

JOURNAL ARTICLE

Suri R, Mallia P, Martin JE, Footitt J, Zhu J, Trujillo-Torralbo M-B, Johnston SL, Grigg Jet al., 2014, Bronchial platelet-activating factor receptor in chronic obstructive pulmonary disease, RESPIRATORY MEDICINE, Vol: 108, Pages: 898-904, ISSN: 0954-6111

JOURNAL ARTICLE

Hatchwell L, Girkin J, Dun MD, Morten M, Verrills N, Toop HD, Morris JC, Johnston SL, Foster PS, Collison A, Mattes Jet al., 2014, Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 133, Pages: 1720-1727, ISSN: 0091-6749

JOURNAL ARTICLE

Privolizzi R, Solari R, Johnston SL, McLean GRet al., 2014, The application of prophylactic antibodies for rhinovirus infections., Antivir Chem Chemother, Vol: 23, Pages: 173-177

Rhinoviruses are extremely common pathogens of the upper respiratory tract with adults experiencing on average 2-5 infections per year and children up to 12 infections. Although infections are not life threatening, except in cases of chronic lung disease where rhinoviruses are the major precipitant of acute exacerbations of disease, there is a high associated economic cost resulting from lost productivity due to absence from work or school. Treatment of infections focuses on symptom relief with anti-pyretics/analgesics as there are no antiviral therapies available and vaccine strategies face difficulties because of the large number of viral serotypes. Here, we assess the potential for prophylactic antibody intervention for these ubiquitous human pathogens.

JOURNAL ARTICLE

Adura PT, Reed E, Macintyre J, del Rosario A, Roberts J, Pestridge R, Beegan R, Boxall CB, Xiao C, Kebadze T, Aniscenko J, Cornelius V, Gern JE, Monk PD, Johnston SL, Djukanovic Ret al., 2014, Experimental rhinovirus 16 infection in moderate asthmatics on inhaled corticosteroids, EUROPEAN RESPIRATORY JOURNAL, Vol: 43, Pages: 1186-1189, ISSN: 0903-1936

JOURNAL ARTICLE

Reed DM, Foldes G, Gatheral T, Paschalaki KE, Lendvai Z, Bagyura Z, Nemeth T, Skopal J, Merkely B, Telcian AG, Gogsadze L, Edwards MR, Gough PJ, Bertin J, Johnston SL, Harding SE, Mitchell JAet al., 2014, Pathogen Sensing Pathways in Human Embryonic Stem Cell Derived-Endothelial Cells: Role of NOD1 Receptors, PLOS ONE, Vol: 9, ISSN: 1932-6203

JOURNAL ARTICLE

Sykes A, Macintyre J, Edwards MR, del Rosario A, Haas J, Gielen V, Kon OM, McHale M, Johnston SLet al., 2014, Rhinovirus-induced interferon production is not deficient in well controlled asthma, THORAX, Vol: 69, Pages: 240-246, ISSN: 0040-6376

JOURNAL ARTICLE

Mahmutovic-Persson I, Akbarshahi H, Bartlett NW, Glanville N, Johnston SL, Brandelius A, Uller Let al., 2014, Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma, ALLERGY, Vol: 69, Pages: 348-358, ISSN: 0105-4538

JOURNAL ARTICLE

Makrinioti H, Toussaint M, Jackson DJ, Walton RP, Johnston SLet al., 2014, Role of interleukin 33 in respiratory allergy and asthma, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 226-237, ISSN: 2213-2600

JOURNAL ARTICLE

Majoor CJ, de Pol MAV, Kamphuisen PW, Meijers JCM, Molenkamp R, Wolthers KC, van der Poll T, Nieuwland R, Johnston SL, Sterk PJ, Bel EHD, Lutter R, van der Sluijs KFet al., 2014, Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study, RESPIRATORY RESEARCH, Vol: 15, ISSN: 1465-993X

JOURNAL ARTICLE

Jayaraman A, Bartlett N, Johnston SL, 2014, Innate and Adaptive Lymphocyte Responses In a Mouse Model Of Rhinovirus-Induced Asthma Exacerbation, Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Publisher: MOSBY-ELSEVIER, Pages: AB135-AB135, ISSN: 0091-6749

CONFERENCE PAPER

Toussaint M, Singanayagam A, Johnston SL, Bartlett Net al., 2014, Role Of Interleukine-33 In Rhinovirus-Induced Allergic Asthma Exacerbation, Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Publisher: MOSBY-ELSEVIER, Pages: AB52-AB52, ISSN: 0091-6749

CONFERENCE PAPER

Gunawardana N, Finney L, Johnston SL, Mallia Pet al., 2014, Experimental rhinovirus infection in COPD: Implications for antiviral therapies, ANTIVIRAL RESEARCH, Vol: 102, Pages: 95-105, ISSN: 0166-3542

JOURNAL ARTICLE

Peel TJ, Jackson DJ, Johnston SL, Walton RPet al., 2014, Il-23, Increased In Asthmatics, Licences Il-17 Secretion In Response To Rhinovirus Infection, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, ISSN: 1073-449X

JOURNAL ARTICLE

Jackson DJ, Shamji B, Trujillo-Torralbo M-B, Walton RP, Bartlett NW, Edwards MR, Mallia P, Edwards M, Westwick J, Johnston SLet al., 2014, Prostaglandin D2 Is Induced During Rhinovirus-Induced Asthma Exacerbations And Related To Exacerbation Severity In Vivo, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, ISSN: 1073-449X

JOURNAL ARTICLE

Ching Y-M, Edwards MR, Glanville N, Johnston SL, Bartlett NWet al., 2014, Innate Type I Interferon Signalling Modulates Th2 Responses In Mouse Models Of Rhinovirus-Induced Airways Disease, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, ISSN: 1073-449X

JOURNAL ARTICLE

Stavrou A, Jolly L, Glanville N, Habgood A, Porte J, Tatler AL, Johnston SL, Blanchard A, Jenkins Get al., 2014, Influenza Infection, But Not Rhinovirus Infection, May Cause Exacerbation Of Lung Fibrosis Through Lung Collagen Deposition, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, ISSN: 1073-449X

JOURNAL ARTICLE

Finney LJ, Ritchie A, Pollard E, Johnston SL, Mallia Pet al., 2014, Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae, INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, Vol: 9, Pages: 1119-1132, ISSN: 1178-2005

JOURNAL ARTICLE

Majoor CJ, Van Der Pol MA, Kamphumen P, Meuers JCM, Van Der Poll T, Molenkamp R, Wolthers KC, Nieuwland R, Johnston SL, Sterk PJ, Bel E, Lulled R, Van Der Sluus KFet al., 2014, Hemostatic Activity Is Associated With Rhinovirus Load In Upper And Lower Airways In Asthma, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 189, ISSN: 1073-449X

JOURNAL ARTICLE

Mallia P, Message SD, Contoli M, Gray K, Telcian A, Laza-Stanca V, Papi A, Stanciu LA, Elkin S, Kon OM, Johnson M, Johnston SLet al., 2014, Lymphocyte subsets in experimental rhinovirus infection in chronic obstructive pulmonary disease, RESPIRATORY MEDICINE, Vol: 108, Pages: 78-85, ISSN: 0954-6111

JOURNAL ARTICLE

Brignull LM, Czimmerer Z, Saidi H, Daniel B, Villela I, Bartlett NW, Johnston SL, Meira LB, Nagy L, Nohturfft Aet al., 2013, Reprogramming of lysosomal gene expression by interleukin-4 and Stat6, BMC GENOMICS, Vol: 14, ISSN: 1471-2164

JOURNAL ARTICLE

Footitt J, Mallia P, Durham A, Trujillo-Torralbo MB, Telcian A, Kebadze T, Aniscenko J, Essilfie-Quaye S, Ito K, Barnes PJ, Elkin S, Kon OM, Adcock I, Johnston SLet al., 2013, HDAC ACTIVITY IN MACROPHAGES IN EXPERIMENTAL RHINOVIRUS INFECTION IN COPD, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A58-A59, ISSN: 0040-6376

CONFERENCE PAPER

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00173317&limit=30&person=true&page=5&respub-action=search.html