Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Asthma UK Clinical Chair



+44 (0)20 7594 3764s.johnston




Mr Christophe Tytgat +44 (0)20 7594 3849




343Norfolk PlaceSt Mary's Campus





MedImmune Inc., MedImmune Inc., Characterisation of a human ICAM-1 transgenic mouse model for determination of the efficacy ofanti-ICAM-1 directed mAbs in major group HRV infection and HRV induced asthma exacerbation., 2010 - 2011

GlaxoSmithKline UK, GlaxoSmithKline UK, Investigating the effects of combined steroid and β2 agonist on innate anti-infective immune responses in epithelial cells and macrophages., 2009 - 2011

AstraZeneca UK, AstraZeneca UK, Anti-ICAM approaches in RV infections., 2009 - 2010

AstraZeneca UK, AstraZeneca UK, Characterising the molecular defect in interferon production in asthma., 2007 - 2010

AstraZeneca UK, AstraZeneca UK, The effect of CCR3 antagonism on RSV transmissibility, 2006 - 2007

Sanofi-Pasteur, Sanofi-Pasteur, Use of adjuvants to manipulate immune responses to rhinovirus infections., 2005 - 2012

Merck Sharp & Dohme Ltd, Merck Sharp & Dohme Ltd, The role of leukotrienes in acute exacerbations of COPD., 2005 - 2007

Centocor, USA, Centocor, USA, Discovery of novel therapies for asthma exacerbations., 2005 - 2011

Pfizer, Pfizer, Development of an experimental model of rhinovirus induced COPD exacerbations., 2005 - 2007

National Jewish Medical study & Research Center,Denver,Colorado, National Jewish Medical study & Research Center,Denver,Colorado, The COPSAC virus study, 2004 - 2006

Millennium Inc, Millennium Inc, Role of epithelial cell costimulatory molecule expression in rhinovirus infection., 2004 - 2005

GlaxoSmithKline, GlaxoSmithKline, Epidemiology of the respiratory viral infections in children aged 12-47 months., 2004 - 2005

Merck Inc, Merck Inc, Previa study, 2003 - 2004

GlaxoSmithKline, GlaxoSmithKline, Development of an experimental model of rhinovirus induced COPD exacerbation., 2001 - 2007

GlaxoSmithKline, GlaxoSmithKline, Molecular mechanisms of inhibition by fluticasone, salmeterol and the combination of rhinovirus induction of pro-inflammatory molecules., 2000 - 2008

SmithKline Beecham USA, SmithKline Beecham USA, The role of virus infections in exacerbations of COPD., 2000 - 2002

SmithKline Beecham USA, SmithKline Beecham USA, The role of p38 kinase in NF-kB activation by rhinovirus., 2000 - 2001

GlaxoWellcome UK, GlaxoWellcome UK, Development of a transgenic mouse model rhinovirus infection and asthma exacerbation., 1999 - 2004

GlaxoWellcome UK, GlaxoWellcome UK, Taqman quantification of virus load in asthma exacerbations., 1998 - 1999

Lederle-Wyeth, Lederle-Wyeth, Role of viral infections in acute wheezing episodes leading to hospital admission in adults., 1997 - 1998

Schering-Plough USA, Schering-Plough USA, Loratidine and mometasone inhibition of rhinovirus induction of ICAM-1., 1997 - 1999

Schering-Plough USA, Schering-Plough USA, A double-blind, placebo controlled study on the effect of Claritin on virus induced wheeze in school children., 1997 - 1999

Abbott Pharmaceuticals, Abbott Pharmaceuticals, Prevalence of chronic Chlamydia pneumoniae infection in normal and asthmatic adults., 1996 - 1998

Hoechst, Hoechst Marrion Roussell, Induction of pro-inflammatory mediators by chronic Chlamydia pneumoniae infection in epithelial cells pneumoniae infection in epithelial cells, 1996 - 1998

Zeneca UK, Zeneca UK, A double blind study on the effect of Accolate of virus-induced asthma exacerbations in adult asthmatic subjects., 1996 - 1998

Prof M Sears, Hamilton Canada

Don Milton, Harvard University

Prof P Holt, Perth Australia

Guest Lectures

At least 20 invited lectures at International Congresses per year

Research Student Supervision

Almond,M, PhD


Chanarin,N, PhD

Chauhan,AJ, PhD

Corne,J, PhD


George,P, PhD


Haas,J, PhD student

Hewson,C, PhD

Hussain,IR, PhD

Jackson,D, PhD


Legg,J, PhD


Mallia,P, PhD

Message,S, PhD

Oliver,B, PhD

Parker,H, PhD




Slater,L, PhD

Sykes,A, PhD

Walton,R, PhD