After reading Chemistry at Oxford, Simon Kroll completed undergraduate medical training at Oxford University Medical School, qualifying in 1980. His initial paediatric training was at Oxford, working under the mentorship of David Baum and Peter Tizard. After MRCP(UK), a short spell in Infectious Diseases at Great Ormond Street led to a Clinical Lectureship, and later a University Lectureship, in Richard Moxon’s Department in Oxford, where during tenure of a Lister Institute Research Fellowship he gained his first consultant post – in Paediatric Infectious Diseases – in 1988. In 1993 he moved to Imperial College and St Mary’s Hospital as Professor of Paediatrics and Molecular Infectious Diseases. He was elected FRCP in 1995, FRCPCH in 1997 and Fellow of the Academy of Medical Sciences in 2001.
From 2000 to 2008 he served two terms as a member of the UK Joint Committee on Vaccination and Immunisation (JCVI), and since 2001 has been a member of the UK Health Protection Agency’s Meningococcus Forum. He is a member of the NICE Meningitis Guideline Development Group, and chairs the Medical and Scientific Advisory Committee of The Meningitis Trust, as well as serving as a member of the Lister Institute of Preventive Medicine’s Scientific Advisory Committee.
The activities of his research group (the Molecular Infectious Diseases Group, MIDG, established with Paul Langford) have focused on the genetic and molecular basis for the virulence of bacterial pathogens, in particular Haemophilus influenzae and Neisseria meningitidis, responsible for life-threatening infections such as meningitis and septicaemia in previously healthy children. He has published over 100 papers in scientific journals on these and related topics.
et al., 2019, Genomic analysis of clostridium perfringens BEC/CPILE-positive, toxinotype D and E strains isolated from healthy children, Toxins, Vol:11, ISSN:2072-6651, Pages:1-14
et al., 2019, Temporal association of the development of oropharyngeal microbiota with early life wheeze in a population-based birth cohort, Ebiomedicine, Vol:46, ISSN:2352-3964, Pages:486-498
et al., 2019, Streaming histogram sketching for rapid microbiome analytics, Microbiome, Vol:7, ISSN:2049-2618
et al., 2018, Characteristics and incidence of transfusion-associated necrotizing enterocolitis in the UK, Journal of Maternal-fetal and Neonatal Medicine, ISSN:1476-4954, Pages:1-6
et al., 2018, Cross-reactive bactericidal antimeningococcal antibodies can be isolated from convalescing invasive Meningococcal disease patients using reverse vaccinology 2.0, Frontiers in Immunology, Vol:9, ISSN:1664-3224